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Filtered Search Results
Apexbio Technology LLC Sulfaphenazole 526-08-9 250mg
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Sulfaphenazole (CAS 526-08-9) is a small-molecule inhibitor targeting cytochrome P450 2C9 (CYP2C9) It is designed to selectively inhibit CYP2C9-mediated drug metabolism thereby informing metabolic pathway studies and investigation of drug-drug interactions Sulfaphenazole exerts its biological activity primarily through competitive inhibition of CYP2C9 In in vitro assays sulfaphenazole demonstrates potent inhibition with a reported Ki value of approximately 0 3 M for human CYP2C9 Based on these pharmacological properties sulfaphenazole holds research potential in evaluating CYP2C9-mediated metabolic processes and associated drug interactions
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eMolecules 1095-85-8 | 2-(Tritylthio)ethanamine | ChemScene | MFCD00822629 | 319.470 | C21H21NS | 95.000 | NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1 | 250mg | 665615743
2-(Tritylthio)ethanamine | ChemScene | 1095-85-8 | MFCD00822629 | 319.470 | C21H21NS | 95.000 | NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1 | 250mg | 665615743
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Medchemexpress LLC 2 4 6-Triphenylanili 250mg
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2 4 6-Triphenylaniline has anti-diabetic activity and can be encapsulated in nano-emulsions (NE) to enhance stability and permeability The NE loaded with 2 4 6-Triphenylaniline inhibits -glucosidase and -amylase[1]
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Medchemexpress LLC GLPG3970 | 2403733-82-2 | C25H27F3N4O4 | 250 MG
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GLPG3970 is a first-in-class SIK2/SIK3 inhibitor intended for research related to inflammation and autoimmune diseases. It has been investigated in clinical trials for conditions such as Systemic Lupus Erythematosus, Ulcerative Colitis, and Rheumatoid Arthritis.
- Acts as a SIK2/SIK3 inhibitor
- Supports research in inflammation and autoimmune diseases
- Induces IL-10 expression in human CD14+ monocytes with an EC50 of 1087 nM
- Reduces LPS-stimulated TNF-alpha production in human CD14+ monocytes with an IC50 of 133 nM
- Decreases ear thickness in murine models of psoriatic-like epidermal hyperplasia
- Improves clinical manifestations in murine collagen-antibody induced arthritis models
- Reduces disease activity index in mice T cell transfer models
- Investigated in clinical trials for various conditions
- High purity: 99.70%
- Solid, white to off-white appearance
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![eMolecules 53902-98-0 | 3-BROMO-2-METHYLPYRAZOLO[1,5-A]PYRIDINE | MFCD22039253 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183006.JPG-250.jpg)
eMolecules 53902-98-0 | 3-BROMO-2-METHYLPYRAZOLO[1,5-A]PYRIDINE | MFCD22039253 | 1g
AstaTech | 3-BROMO-2-METHYLPYRAZOLO[1,5-A]PYRIDINE | 1g | 323621246 | 89514 | 95.000 | 53902-98-0 | MFCD22039253 | 211.062 | C8H7BrN2
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eMolecules 333-27-7 | Methyl trifluoromethanesulfonate | Chem-Impex | MFCD00000409 | 164.100 | C2H3F3O3S | 96.000 | COS(=O)(=O)C(F)(F)F | 25g | 809116506
Methyl trifluoromethanesulfonate | Chem-Impex | 333-27-7 | MFCD00000409 | 164.100 | C2H3F3O3S | 96.000 | COS(=O)(=O)C(F)(F)F | 25g | 809116506
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Medchemexpress LLC Ethyl Caffeate | 102-37-4 | 25 MG
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Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. It suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin. It is for research use only and not sold to patients.
- Suppresses NF-κB activation
- Inhibits inflammatory mediators, including iNOS, COX-2, and PGE2
- Markedly suppresses LPS-induced nitric oxide (NO) production
- Targets iNOS, NF-κB, and COX-2
- Isolated from Bidens pilosa
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![eMolecules 55457-11-9 | 7-Methylpyrazolo[1,5-a][1,3,5]triazin-4(3H)-one | MFCD11870778 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502141621.JPG-250.jpg)
eMolecules 55457-11-9 | 7-Methylpyrazolo[1,5-a][1,3,5]triazin-4(3H)-one | MFCD11870778 | 1g
Ambeed | 7-Methylpyrazolo[1,5-a][1,3,5]triazin-4(3H)-one | 1g | 591797706 | A166405 | 55457-11-9 | MFCD11870778 | 150.141 | C6H6N4O
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eMolecules 101-38-2 | Gibbs reagent | TargetMol | MFCD00001611 | 210.440 | C6H2Cl3NO | 0.000 | ClN=C1C=C(Cl)C(=O)C(Cl)=C1 | 250mg | 812268369
Gibbs reagent | TargetMol | 101-38-2 | MFCD00001611 | 210.440 | C6H2Cl3NO | 0.000 | ClN=C1C=C(Cl)C(=O)C(Cl)=C1 | 250mg | 812268369
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Medchemexpress LLC Tridecanedioic acid | 505-52-2 | 99.9% | 250 MG
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Tridecanedioic acid, also known as Brassylic Acid, is a chemical substance with the formula C13H24O4 and a molecular weight of 244.33. It appears as a white to off-white solid. This product is stable under recommended storage conditions and is not classified as a hazardous substance or mixture.
- High purity, with HPLC analysis showing 99.9%
- Stable under recommended storage conditions
- Supplied as a solid
- Chemical formula C13H24O4
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Medchemexpress LLC Troxipide | 30751-05-4 | MFCD00866876 | 99.6% | 250 MG
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Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). It is a non-antisecretory gastroprotective agent with antiulcer, anti-inflammatory, and mucus-secreting properties.
- Enhances gastric mucosal blood flow and gastric mucosal defense factors.
- Promotes tissue repair, blood circulation, metabolism, and gastric ulcer (GU) repair.
- Exerts inhibitory, therapeutic, and preventive effects specifically in the stomach.
- Significantly alleviates gastric ulcer (GU).
- Reduces levels of IL-17, IL-6, TNF-α, IFN-γ, and AP-1 in gastric ulcer models.
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Medchemexpress LLC GANT 61 | 500579-04-4 | 99.80% | 429.60 | 25 MG
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GANT 61 is a potent inhibitor of Gli1 and Gli2, effectively targeting the Hedgehog/GLI signaling pathway. This compound has demonstrated significant biological activity both in vitro and in vivo, impacting cell proliferation, viability, and tumor growth across various cancer models.
- Inhibits Gli1 and Gli2 activity
- Targets the Hedgehog/GLI pathway
- Reduces clonogenic survival in human colon carcinoma cells
- Induces apoptosis and inhibits cell viability in pancreatic cancer stem cells
- Inhibits motility, invasion, and migration of cancer stem cells
- Decreases tumor growth in xenograft models
- Enhances the effects of chemotherapeutic drugs for neuroblastoma
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Medchemexpress LLC Methyl cellulose | 9004-67-5 | MFCD00081763 | 98.0% | C6H7O2(OR1)(OR2)(OR3) (polymeric repeat unit) | 25G
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Methyl cellulose is a non-ionic cellulose ether supplied as a powder with a nominal viscosity of 40,000 mPa·s. It dissolves in water with warming and ultrasonic treatment to form viscous solutions and gels used as thickeners, stabilizers, and gel-forming agents for laboratory formulations, assay reagents, and viscosity modification. Recommended storage is sealed at 4°C; solutions have specified short-term stability at -20°C and long-term stability at -80°C per datasheet.
- High-viscosity aqueous thickener for formulation and assay work.
- Soluble in water (approx. 10 mg/mL) with heating and sonication.
- Forms thermogel on heating and stabilizes emulsions and suspensions.
- Supplied as a 25 g powder for laboratory use.
- Polymeric material with variable molecular weight; no single fixed formula.
- SDS and technical datasheet available for handling, solubility, and storage details.
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Medchemexpress LLC Methyl pyrimidine-2-carboxylate | 34253-03-7 | 99.8% | C6H6N2O2 | 25 G
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Methyl pyrimidine-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It also serves as a synthetic intermediate for pharmaceutical synthesis.
- Applicable as a biological material
- Useful as an organic compound for life science research
- Synthetic intermediate for pharmaceutical synthesis
- Off-white to yellow solid appearance
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Frontier Specialty Chemicals 1G PYRIMIDINE-5-CARBOXYLIC ACI
This item has a minimum qty of 12 per supplier requirements.
Pyrimidine-5-carboxylic acid; CAS No: 4595-61-3
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