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Filtered Search Results
Medchemexpress LLC N-succinimidyl iodoacetate | 39028-27-8 | MFCD00058451 | >95.0% | 283.02 | C6H6INO4 | 250 MG
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SIA Crosslinker (N-succinimidyl iodoacetate) is a short, heterobifunctional crosslinker used to form stable amine-to-sulfhydryl conjugates. It serves as a non-cleavable ADC linker and is used for protein-protein and protein-small molecule conjugation.
- Amine- and sulfhydryl-reactive (NHS ester and iodoacetyl).
- Very short spacer arm (~1.5 Å) for minimal linkage length.
- Molecular weight 283.02, formula C6H6INO4, CAS 39028-27-8.
- Used for antibody-drug conjugates and general protein conjugation.
- Available in common laboratory package sizes (100 mg, 250 mg, 500 mg).
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Medchemexpress LLC (4-nitrophenyl) 2-(pyridin-2-yldisulfanyl)ethyl carbonate | 874302-76-8 | MFCD28556879 | 99.9% | 352.4 g/mol | C14H12N2O5S2 | 250 MG
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PDEC-NB is a disulfide-cleavable carbonate linker used to construct antibody-drug conjugates (ADCs). It contains an activated 4-nitrophenyl carbonate and a pyridin-2-yldisulfanyl moiety that enables release of payloads under reducing intracellular conditions.
- Provides disulfide cleavable linkage for intracellular payload release
- Contains an activated 4-nitrophenyl carbonate for efficient conjugation
- White to off-white solid suitable for low-temperature storage
- Available in mg to gram scale quantities for research use
- High purity appropriate for research applications
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Medchemexpress LLC (2-pyridyldithio)-PEG1-hydrazine | 111625-28-6 | MFCD22551638 | 99.3% | 187.28 g/mol | C7H9NOS2 | 250 MG
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(2-pyridyldithio)-PEG1-hydrazine is a cleavable, single-unit PEG linker used for constructing antibody-drug conjugates (ADCs). It provides a pyridyldithio cleavable moiety and a hydrazine functional group for flexible conjugation and controlled payload release.
- Cleavable pyridyldithio linker enabling disulfide-mediated payload release.
- Single-unit PEG spacer to improve solubility and reduce steric hindrance.
- Hydrazine functional handle for versatile conjugation chemistries.
- Supplied in small research-scale quantities suitable for linker development.
- Storage and stability guidance provided for refrigerated and solvent conditions.
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Medchemexpress LLC DBCO-acid | 1353016-70-2 | 99.7% | 305.33 g/mol | C19H15NO3 | 250 MG
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DBCO-acid is a strain-promoted alkyne reagent used in bioorthogonal click chemistry (SPAAC) to conjugate azide-containing molecules. It is commonly applied in the synthesis of antibody-drug conjugate linkers and agent-linker conjugates.
- Strain-promoted alkyne reagent for SPAAC conjugation to azide-containing molecules.
- Commonly used to synthesize ADC linkers and agent-linker conjugates.
- Chemical formula C19H15NO3; molecular weight 305.33 g/mol.
- Purity 99.7%; CAS number 1353016-70-2.
- Soluble in DMSO (~100 mg/mL); hygroscopic-use freshly opened DMSO.
- Store at 4°C under inert gas; in solution store at -80°C (up to 6 months) or -20°C (up to 1 month).
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Medchemexpress LLC Auristatin E | 160800-57-7 | MFCD25976744 | 99.9% | 732.01 g/mol | C40H69N5O7 | 250 MG
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Auristatin E is a synthetic cytotoxic peptide that inhibits microtubule polymerization and is used as a payload in antibody-drug conjugate research. It is an analogue of dolastatin 10 and blocks cell division by preventing tubulin polymerization.
- High purity suitable for research applications.
- Inhibits tubulin polymerization to block cell division.
- Used as a cytotoxic payload in antibody-drug conjugate research.
- Contains CAS number 160800-57-7 and molecular weight 732.01 g/mol.
- Available in laboratory pack sizes, including a 250 mg option.
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Medchemexpress LLC PROPOFOL IMPURITY 1 250MG
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5000204519 PROPOFOL IMPURITY 1 250MG
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Medchemexpress LLC 2-Heptenoic acid 250mg
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2-Heptenoic acid is an unsaturated fatty acid It is a clear colorless liquid with a strong odour and is commonly used in the flavor and fragrance industry for its pungent anise-like odor In addition it can be used as an intermediate in the synthesis of other organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in a variety of industrial applications including food and beverage production cosmetics and personal care products
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Medchemexpress LLC Pantoprazole impurit 250mg
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Pantoprazole impurity 26 is an impurity of Pantoprazole (HY-17507)
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Medchemexpress LLC 2 6-Dichloroquinone- 250mg
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2 6-Dichloroquinone-4-chloroimide is a spray reagent for organic compounds 2 6-Dichloroquinone-4-chloroimide can be used in thin-layer chromatograms and detecting phenol and its derivatives 2 6-Dichloroquinone-4-chloroimide can be used as an optical sensor for rapid detection of permethrin in treated wood[1][2][3][4]
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Medchemexpress LLC 5-Cholanic acid 500mg
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5 -Cholanic acid is a hydrophobic modifier used to modify polymer carriers 5 -Cholanic acid can improve the acid stability cell penetration efficiency and drug sustained release ability of nanocarriers and optimize the oral effectiveness of delivered molecules 5 -Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells) 5 -Cholanic acid can be used in the development of drug delivery systems[1][2]
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Medchemexpress LLC Ethyl cellulose 1kg
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Ethyl cellulose is a derivative of cellulose Ethyl cellulose is a non-toxic biodegradable polymer Ethyl cellulose has unique properties such as oil gel formation active ingredient delivery and film formation Ethyl cellulose can be used as a pharmaceutical excipient such as a coating agent flavoring agent tablet filler etc Ethyl cellulose can be used to prepare nanoparticles for active compound delivery[1][2][3][4]
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Medchemexpress LLC 1 8-Bismaleimidotrie 250mg
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1 8-Bismaleimidotriethyleneglycol is a biochemical reagent
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Medchemexpress LLC 3-Aminopropylphospho 250mg
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3-Aminopropylphosphonic acid ((3-Aminopropyl)phosphonic acid) is a phosphonic acid analogue of GABA and a GABAB receptor agonist[1][2]
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Medchemexpress LLC Guaiacylglycerol-bet 250mg
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Guaiacylglycerol-beta-guaiacyl ether is a model compound of lignin monomers that can be degraded by Bacillus amyloliquefaciens CotA[1]
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Medchemexpress LLC 5-CHOLANIC ACID 25MG
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5000205375 5-CHOLANIC ACID 25MG
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