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Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
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Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. It is also commonly used to detect or assess PAH pollution in the environment.
Reduces mitochondrial membrane potential (MMP) in primary hepatocytes.
Induces oxidative stress and inflammation.
Causes liver damage and promotes hepatocyte apoptosis.
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