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Aromatic organic compounds that consist of an aromatic six-membered ring containing two non-adjacent nitrogen atoms and four carbon atoms; includes compounds derived from pyrimidines.
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DKM 2-93 is a covalent, relatively selective inhibitor of ubiquitin-like modifier activating enzyme 5 (UBA5) used for biochemical and cellular research. It inhibits UBA5 by covalently modifying the catalytic cysteine (reported biochemical IC50 ≈ 430 μM) and reduces viability of PaCa-2 and Panc-1 cells in cellular assays. The compound is supplied as a solid or as DMSO solutions; reported purity is 98.76% and molecular weight is 243.69.
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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