Bisoprolol hemifumarate is a potent, selective, and orally active β1-adrenergic receptor blocker with minimal activity on β2-receptors. This compound is used in research for hypertension, coronary artery disease, and stable ventricular dysfunction studies.
- Potent and selective β1-adrenergic receptor blocker
- Orally active
- Minimal β2-receptor activity
- Protects myocardial cells from ischemia/reperfusion injury
- Reduces ROS production and apoptosis
- Increases AKT and GSK3β phosphorylation
- Supports research in hypertension
- Supports research in coronary artery disease
- Supports research in stable ventricular dysfunction
- Increases left ventricular ejection fraction
- Decreases heart rate
- Shows protective effects against cadmium-induced myocardial toxicity
- Reverses small conductance calcium-activated potassium channel remodeling