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Pt-ttpy is a platinum-based metallo-organic complex that selectively binds G-quadruplex DNA structures. It has been reported to induce telomere-related DNA damage, inhibit telomerase activity, and produce chromatin abnormalities during mitosis, making it a useful reagent for studies of telomere biology and anticancer mechanisms.
Binds G-quadruplex DNA structures.
Induces telomere-related DNA damage in cancer cells.
Inhibits telomerase and disrupts telomere function.
Causes mitotic chromatin abnormalities such as bridges and double-stranded breaks.
Useful as a research reagent for telomere biology and G-quadruplex studies.
Provided with high purity suitable for biochemical assays.
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