Pyrroles
Apexbio Technology LLC AHU-377 hemicalcium salt 1369773-39-6 10mg
AHU-377 hemicalcium salt (CAS 1369773-39-6) is a hemicalcium salt form of AHU-377 a potent inhibitor of neprilysin (neutral endopeptidase) with an IC50 of 5 nM As a prodrug AHU-377 is enzymatically converted to its active metabolite LBQ657 following ester cleavage AHU-377 is a key component of LCZ696 co-formulated with valsartan at a 1 1 molar ratio functioning as an angiotensin receptor neprilysin inhibitor (ARNI) In vivo studies demonstrate that oral administration of AHU-377 induces dose-dependent blood pressure reduction in DAHI-SS rats though it has less pronounced effects in DOCA-salt hypertensive models AHU-377 is widely studied in cardiovascular research particularly in the context of heart failure and hypertension
eMolecules 4-AMINO-1-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID HCL | 198765-34-3 | MFCD18782086 | 1g
AstaTech | 4-AMINO-1-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID HCL | 1g | 222806267 | 84211 | 95.000 | 198765-34-3 | MFCD18782086 | 176.600 | C6H9ClN2O2
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eMolecules Building Block Tool
Apexbio Technology LLC Pyrrole-2-carboxylic acid 634-97-9 1g
Pyrrole-2-carboxylic acid (CAS 634-97-9) is a heterocyclic organic compound characterized by a carboxyl substituent at the 2-position of the pyrrole ring This molecule has been investigated in biomedical research as an inhibitor of certain enzymatic pathways involving pyrrole derivatives including roles in microbial metabolism and secondary metabolite biosynthesis Pyrrole-2-carboxylic acid is utilized in studies examining enzyme specificity metabolic pathway modulation and as a precursor in the synthesis of pharmacologically relevant molecules Its defined structure makes it a valuable tool for probing pyrrole-related biochemical mechanisms
Selleck Chemical LLC LLY-507-5mg
LLY-507 is a cell-active, potent, and selective inhibitor of protein-lysine Methyltransferase SMYD2.
Medchemexpress LLC Pravastatin lactone | 85956-22-5 | 99.2% | 5 MG
Pravastatin lactone is the delta-lactone metabolite of pravastatin and a potent inhibitor of HMG-CoA reductase. It is used as a research reagent to study statin metabolism and cholesterol biosynthesis in biochemical and pharmacological assays.
- Potent HMG-CoA reductase inhibitor used in cholesterol synthesis studies.
- High purity suitable for analytical and biochemical applications.
- Available in small milligram quantities for assay development and metabolism studies.
- Molecular formula C23H34O6 and molecular weight 406.51 g/mol aid identification and dosing.
- Provided as a neat solid for laboratory research use.
Cayman Chemical 4-hydroxy Atorvastatin lacton
A metabolite of atorvastatin; formed by metabolism of atorvastatin by CYP3A4
eMolecules Medchem Express / CMK / 2mg / 446271303 / HY-52101 / / 821794-90-5 / MFCD18379168 / 358.830 / C18H19ClN4O2
Medchem Express / CMK / 2mg / 446271303 / HY-52101 / / 821794-90-5 / MFCD18379168 / 358.830 / C18H19ClN4O2
Medchemexpress LLC Atorvastatin epoxy tetrahydrofuran impurity | 873950-19-7 | MFCD31700699 | 96.0% | C26H24FNO5 | 10MG
Atorvastatin epoxy tetrahydrofuran impurity is an oxidative degradation product of atorvastatin provided as an analytical reference standard for research use. Supplied in milligram quantities, it supports impurity profiling, method development, and stability testing. Users should consult the lot-specific Certificate of Analysis for purity and storage conditions.
- Used as an impurity reference for analytical method development.
- Suitable for stability studies and degradation profiling.
- Provided in small, laboratory-scale quantities for research use.
- Chemical formula C26H24FNO5 and CAS 873950-19-7 for unambiguous identification.
- Lot-specific purity and storage conditions available in the Certificate of Analysis.
![eMolecules Hexahydrocyclopenta[c]pyrrol-1(2H)-one | ChemScene | 56593-76-1 | MFCD06797719 | 125.171 | C7H11NO | 95.000 | O=C1NCC2CCCC12 | 50mg | 859965524](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3729573.JPG-250.jpg)
eMolecules Hexahydrocyclopenta[c]pyrrol-1(2H)-one | ChemScene | 56593-76-1 | MFCD06797719 | 125.171 | C7H11NO | 95.000 | O=C1NCC2CCCC12 | 50mg | 859965524
Hexahydrocyclopenta[c]pyrrol-1(2H)-one | ChemScene | 56593-76-1 | MFCD06797719 | 125.171 | C7H11NO | 95.000 | O=C1NCC2CCCC12 | 50mg | 859965524
Selleck Chemical LLC Atorvastatin Calcium S2077-500mg
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol Atorvastatin Calcium induces apoptosis and autophagy
Selleck Chemical LLC Sunitinib malate S1042-1g
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR with IC50 of 80 nM and 2 nM in cell-free assays and also inhibits c-Kit Sunitinib Malate effectively inhibits autophosphorylation of Ire1 Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis
Medchemexpress LLC HY-12861 10mg Medchemexpress, CB-5083 CAS:1542705-92-9 Purity:>98%
Medchemexpress, HY-12861 10mg CB-5083 CAS:1542705-92-9 CB-5083 is a potent, selective and orally bioavailable p97 inhibitor with an IC50 value of 11 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15772 10mg Medchemexpress, Osimertinib CAS:1421373-65-0 Purity:>98%
Medchemexpress, HY-15772 10mg Osimertinib CAS:1421373-65-0 Osimertinib (AZD-9291) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-70062 10mg Medchemexpress, Pevonedistat CAS:905579-51-3 Purity:>98%
Medchemexpress, HY-70062 10mg Pevonedistat CAS:905579-51-3 Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Tubastatin A HCl-10mg
Tubastatin A HCl (TSA) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more).