Pyrroles
Medchemexpress LLC HY-111378 5mg Medchemexpress, Casein Kinase II Inhibitor IV CAS:863598-09-8 Purity:>98%
Medchemexpress, HY-111378 5mg Casein Kinase II Inhibitor IV CAS:863598-09-8 Casein Kinase II Inhibitor IV is a small-molecule inducer of epidermal keratinocyte differentiation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 1-Furfurylpyrrole | 1438-94-4 | 99.07% | 1 ML
1-Furfurylpyrrole is a chemical compound identified as a potential contributor to the flavor and aroma of popcorn.
- Enhances flavor and aroma profile, specifically noted for its contribution to popcorn.
- High purity of 99.07%.
- Soluble in DMSO at 100 mg/mL for in vitro studies.
- Intended for research use only.
eMolecules 172732-68-2 | Medchem Express | Varespladib | 5mg | 446262827 | HY-13402 | MFCD00944812 | 380.4 | C21H20N2O5
Medchem Express | Cbl-b-IN-2 | 5mg | 788478274 | HY-141431 | 2503325-21-9 | 575.584 | C29H30F5N5O2
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Medchemexpress LLC JNJ-63576253 | 25MG
JNJ-63576253 (TRC-253) is a potent and orally active full antagonist of androgen receptor (AR) with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC)[1]
eMolecules 1049741-03-8 | Medchem Express | SPD304 (dihydrochloride) | 5mg | 761953613 | HY-111255A | MFCD09265259 | 620.54 | C32H34Cl2F3N3O2
Medchem Express | Ascr5 | 5mg | 600899991 | HY-N6978 | 1086696-26-5 | 220.221 | C9H16O6
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Medchemexpress LLC HY-15424 2mg Medchemexpress, 5-Iodotubercidin CAS:24386-93-4 Purity:>98%
Medchemexpress, HY-15424 2mg 5-Iodotubercidin CAS:24386-93-4 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Jnj-18038683 | 851376-05-1 | 99.8% | 529.97 g/mol | C26H28ClN3O7 | 10 MG
This small-molecule research compound is a selective antagonist of the 5-hydroxytryptamine type 7 (5-HT7) receptor used in pharmacology and neuroscience studies. It shows high affinity in binding assays (pKi ≈ 8.19-8.20 for rat and human 5-HT7 in HEK293 cells), produces concentration-dependent inhibition of 5-HT-stimulated adenylyl cyclase, and alters REM sleep in rodent models. Supplied as a solid or as a DMSO solution for in vitro and in vivo research.
- Selective 5-HT7 receptor antagonist with high binding affinity.
- Demonstrated functional antagonism in adenylyl cyclase assays.
- Modulates REM sleep parameters in rodent studies.
- High purity suitable for research applications.
- Available as solid and ready-to-use DMSO solution.
- Store sealed and protect from moisture; follow supplier storage guidelines.
Selleck Chemical LLC Ribociclib
Ribociclib is an orally available and highly specific inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM Phase 3
Medchemexpress LLC JMS-17-2 | 1380392-05-1 | MFCD30489012 | 99.2% | 419.95 | C25H26ClN3O | 50MG
JMS-17-2 is a small-molecule research compound that functions as a potent and selective antagonist of the CX3CR1 receptor (IC50 = 0.32 nM). It has been used in preclinical studies to impair metastatic seeding and colonization of breast cancer cells. The material is supplied as a high-purity solid with recommended cold storage for prepared solutions to preserve stability.
- Chemical formula: C25H26ClN3O.
- Molecular weight: 419.95 g·mol-1.
- High purity suitable for research use.
- Appearance: white to off-white solid.
- Storage: store solid at 4°C protected from light; store solutions at -20°C to -80°C for longer-term stability.
- Applications: in vitro and in vivo studies of CX3CR1-mediated processes and metastasis models.
- Available in multiple pack formats including small mg quantities and ready-to-use DMSO solutions.
Active Motif Tubastatin A hydrochloride
Active Motif's Potent and selective histone deacetylase 6 (HDAC 6) inhibitor (IC50 = 15 nm; >1000-fold selective against other HDACs and 60-fold for HDAC8)). Inhibits TNF_ (IC50 = 272 nm) and IL-6 (IC50 = 712 nm) in LPS-stimulated human macrophages and displays anti-inflammatory activity in animal models. Improves survival in animal models of sepsis. Improves cognition in Alzheimers disease transgenic mice. It is cell permeable.
![Medchemexpress LLC 5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one | 1380392-05-1 | MFCD30489012 | 99.2% | 419.95 g/mol | C25H26ClN3O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235067.png-250.jpg)
Medchemexpress LLC 5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one | 1380392-05-1 | MFCD30489012 | 99.2% | 419.95 g/mol | C25H26ClN3O | 10MG
JMS-17-2 is a potent, selective antagonist of the chemokine receptor CX3CR1 used in research to inhibit CX3CR1-mediated signaling. It shows an IC50 of 0.32 nM and has been reported to impair metastatic seeding and colonization of breast cancer cells, making it useful for in vitro pharmacology and cell-based assays.
- Potent CX3CR1 inhibition (IC50 0.32 nM).
- High reported purity (99.18%).
- Defined chemical characteristics: C25H26ClN3O, MW 419.95 g/mol.
- Solid, white to off-white appearance.
- Storage: in solvent, -80 °C up to 6 months; -20 °C up to 1 month; protect from light.
- Relevant for studies of metastatic seeding and colonization in cancer research.
Medchemexpress LLC HY-108637 10mg Medchemexpress, PhiKan 083 CAS:880813-36-5 Purity:>98%
Medchemexpress, HY-108637 10mg PhiKan 083 CAS:880813-36-5 PhiKan 083 is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM, and a relative binding affinity (Kd) of 150 μM in Ln229 cells[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.