Pyrroles
Medchemexpress LLC Varespladib methyl | 172733-08-3 | 99.9% | 394.42 g/mol | C22H22N2O5 | 10 MG
Varespladib methyl is a small-molecule research compound that selectively inhibits group II secretory phospholipase A2 (sPLA2). It is supplied as a high-purity solid for biochemical and pharmacological studies, and is commonly used in in vitro enzyme inhibition assays, mechanistic studies of inflammatory pathways, and preclinical research on venom neutralization.
- Selective inhibitor of group II secretory phospholipase A2 (sPLA2).
- High purity suitable for research use (reported 99.90%).
- Molecular formula C22H22N2O5; molecular weight 394.42 g/mol.
- Available in small vial sizes for laboratory workflows.
- Suitable for in vitro assays and preclinical studies involving PLA2 pathways.
Selleck Chemical LLC Sunitinib malate S1042-500mg
Sunitinib malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFR with IC50 of 80 nM and 2 nM in cell-free assays and also inhibits c-Kit Sunitinib Malate effectively inhibits autophosphorylation of Ire1 Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis
Medchemexpress LLC HY-B0595 50mg Medchemexpress, Ramosetron (Hydrochloride) CAS:132907-72-3 Purity:>98%
Medchemexpress, HY-B0595 50mg Ramosetron (Hydrochloride) CAS:132907-72-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
AdipoGen Sunitinib . malate (25 mg)
Chemical. CAS: 341031-54-7. Formula: C22H27FN4O2 . C4H6O5. MW: 398.5 . 134.1. Potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor targeting VEGFR and PDGFR-beta. Inhibits FLK1 (Ki=9nM), PDGFRbeta (Ki=8nM) and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine kinases in a panel, including EGFR, Cdk2, Met, IGFR-1, Abl and Src. Inhibits the cellular receptor phosphorylation of FLT3, RET and CSF-1R. Also shown to inhibit c-Kit. Exhibits potent antiangiogenic and antitumor activity in multiple xenograft models.
Medchemexpress LLC HY-12746 5mg Medchemexpress, DC-05 CAS:890643-16-0 Purity:>98%
Medchemexpress, HY-12746 5mg DC-05 CAS:890643-16-0 DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 10.3 μM and 1.09 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-12981 5mg Medchemexpress, RG7713 CAS:920022-47-5 Purity:>98%
Medchemexpress, HY-12981 5mg RG7713 CAS:920022-47-5 RG7713 (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ac-YVAD-cmk | 178603-78-6 | MFCD00237124 | 98.9% | 540.99 g/mol | C24H33ClN4O8 | 10 MG
Ac-YVAD-cmk is a peptide-based, irreversible inhibitor of caspase-1 (interleukin-1β converting enzyme) used in biochemical and cell-based research to block caspase-1 activity and reduce maturation of proinflammatory cytokines. It is commonly applied in studies of inflammation, pyroptosis, and neuroprotection.
- Selective inhibition of caspase-1 activity in biochemical assays and cell models.
- Irreversible peptide-based inhibitor for sustained target engagement.
- Reduces processing of IL-1β and IL-18 in inflammasome-related research.
- High supplied purity suitable for research applications.
- Available in multiple pack sizes and as a ready-to-use DMSO solution.
- Accompanied by datasheet, SDS, and certificate of analysis for reproducible experiments.
Apexbio Technology LLC Sunitinib malate(Synonyms: Sutent, SU11248, Sunitinib L-malate, Sunitinib malate salt, SU-11248 malate, Sutent malate), 1g, CAS: 341031-54-7.
Sunitinib malate (CAS 341031-54-7) is a small molecule orally bioavailable multitargeted receptor tyrosine kinase inhibitor It inhibits various receptor tyrosine kinases including platelet-derived growth factor receptor (PDGFR) vascular endothelial growth factor receptors (VEGFR-1 2 and 3) c-KIT FLT3 kinase colony-stimulating factor-1 receptor (CSF-1R) and RET kinase In neuroblastoma cell lines (e g SK-N-BE(2) SH-SY5Y LAN-5) treatment with sunitinib malate significantly suppresses proliferation in a dose-dependent manner (IC50 10-20 ng/ml) Preclinical studies show tumor growth inhibition and reduced metastasis in neuroblastoma mouse models highlighting its potential for research in oncology therapeutics
eMolecules Ethyl 5-amino-1-(3-fluorophenyl)-1h-pyrazole-4-carboxylate | 138907-70-7 | MFCD13176482 | 1g
Combi-Blocks | Ethyl 5-amino-1-(3-fluorophenyl)-1h-pyrazole-4-carboxylate | 1g | 448008208 | QY-3239 | 95.000 | 138907-70-7 | MFCD13176482 | 249.245 | C12H12FN3O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Bromoenol lactone | 88070-98-8 | MFCD00270871 | ≥98.0% | 317.18 g/mol | C16H13BrO2 | 5 MG
Bromoenol lactone is a small-molecule, suicide-based irreversible inhibitor of calcium-independent phospholipase A2 (iPLA2). It is commonly used in biochemical and cellular research to probe iPLA2-related signaling, study lipid metabolism, and inhibit enzyme activity in assays and cell models.
- Irreversible inhibition of calcium-independent phospholipase A2 (iPLA2).
- Applicable to enzymatic assays and cell-based studies.
- Used to investigate lipid metabolism and signaling pathways.
- Provided in small research-scale quantities for laboratory use.
Medchemexpress LLC STING agonist-3 trihydrochloride | 98.4% | 860.19 | C37H45Cl3N12O6 | 10 MG
STING agonist-3 trihydrochloride is a selective, non-nucleotide small-molecule agonist of STING used for research in immunology and oncology. Supplied as the trihydrochloride salt in a solid, white to off-white form, it is characterized by molecular formula C37H45Cl3N12O6, molecular weight 860.19, and high purity (98.36%).
- Selective non-nucleotide STING agonist with demonstrated activity in preclinical models.
- Molecular formula C37H45Cl3N12O6; molecular weight 860.19.
- High purity (98.36%) suitable for research applications.
- Supplied as a solid; recommended dissolution in DMSO for in vitro use.
- Storage recommendations: solid at 4°C (protect from light); in solution store at -80°C for long-term.
Cayman Chemical Losartn CarboxylIc AcId 50mg
An AT1b receptor antagonist and active metabolite of losartan; an antagonist of AT1b (Kis = 0.67 nM in COS-7 cells expressing the human receptor); selective for AT1b over AT2 (Ki = >10,000 nM in COS-7 cells expressing the human receptor); reduces U-44619-induced aggregation of platelets in isolated human platelet-rich plasma at 50 µM; reduces MAP in water-deprived rats at 1 mg/kg
eMolecules (2-Pyrrol-1-yl-phenyl)-methanol | 61034-86-4 | MFCD04115123 | 25g
J & W PharmLab LLC | (2-Pyrrol-1-yl-phenyl)-methanol | 25g | 452547040 | 72R0004 | 96.000 | 61034-86-4 | MFCD04115123 | 173.215 | C11H11NO
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool