Pyrroles
Medchemexpress LLC Massoia lactone | 54814-64-1 | 25 G
Massoia lactone is a coconut and creamy fragrant compound primarily isolated from Cryptocarya massoy. It is also known as a fragrant biosurfactant produced by the fungus Aureobasidium pullulans.
- Coconut and creamy fragrant compound
- Primarily isolated from Cryptocarya massoy
- Functions as a fragrant biosurfactant
- Produced by Aureobasidium pullulans
- Molecular weight: 168.23
- Chemical formula: C10H16O2
- Appearance: Liquid
- Color: Light yellow to light brown
- Purity: 98.75%
- Storage (pure form): -20°C for 3 years
Medchemexpress LLC (3S,5S)-Atorvastatin | 501121-34-2 | 95.0% | 100 MG
(3S,5S)-Atorvastatin is an inactive enantiomer of Atorvastatin and can activate the pregnane X receptor (PXR). Atorvastatin is an orally active HMG-CoA reductase inhibitor that effectively decreases blood lipids.
- (3S,5S)-Atorvastatin increases CYP2B and CYP3A mRNA content with equal ability as atorvastatin.
- It induces luciferase activity with an EC50 of 12.4 μM at 100 μM concentrations.
- The addition of (3S,5S)-Atorvastatin to a 2-formylphenylboronic acid (FPBA)/l-tryptophanol mixture enhances the intensity of l-tryptophanol fluorescence.
Medchemexpress LLC Benzenamine, 4,4',4'-methylidynetris- | 548-61-8 | ≥98.0% | 1 ML
Tris(4-aminophenyl)methane is a triphenylmethane dye and a weak HCV helicase inhibitor. It shows 30% inhibition at 100 μM against HCV helicase and can be used as an RNA preservative in biological samples.
- Triphenylmethane dye
- Weak HCV helicase inhibitor
- Shows 30% inhibition at 100 μM against HCV helicase
- Can be used as an RNA preservative in biological samples
- Precipitates RNA in an aqueous solution
- Can be applied in immunostaining assays and other histochemical methods
Medchemexpress LLC Atorvastatin sodium | 134523-01-6 | MFCD08458204 | 99.9% | 580.6 g/mol | C33H34FN2NaO5 | 1 ML
Atorvastatin sodium is the sodium salt of atorvastatin, an HMG-CoA reductase inhibitor used in research on lipid metabolism, cardiovascular biology, and inflammation. It is supplied at high purity and is available as solids and as a 10 mM solution in DMSO for biochemical and cell-based assays.
- High purity suitable for research (≈99.9%).
- Available as 10 mM DMSO solution for ready-to-use dosing.
- Also available as multiple solid weights for formulation or storage.
- Used in assays targeting HMG-CoA reductase and related pathways.
- Documented activity in cellular and in vivo cardiovascular models.
Medchemexpress LLC TLR7/8-IN-1 | 2205095-75-4 | MFCD34567724 | 99.9% | C29H40N8O2 | 10MG
TLR7/8-IN-1 is a crystalline small-molecule inhibitor of Toll-like receptors 7 and 8, described in patent WO2019220390 (compound 2b). It is supplied as a high-purity research reagent for studies of TLR-mediated signaling and autoimmune disease.
- High purity (99.9%).
- White to off-white solid appearance.
- Molecular formula C29H40N8O2; molecular weight 532.68 g·mol⁻¹.
- Available in multiple pack sizes and solution formats (10 mM in DMSO).
- Intended for research use in TLR7/TLR8 biology and autoimmune disease models.
Medchemexpress LLC Jnj-42226314 | 1252765-13-1 | MFCD32671350 | 99.4% | C26H24FN5O2S | 10MG
JNJ-42226314 is a selective, reversible, non-covalent monoacylglycerol lipase (MAGL) inhibitor supplied for laboratory research. It is used in biochemical and cellular studies to investigate MAGL function and endocannabinoid signaling and is provided as a high-purity material suitable for assay development and mechanistic work.
- Selective, reversible non-covalent MAGL inhibitor.
- High purity (99.4%).
- Suitable for biochemical and cellular assays.
- Provided in small research quantities (10 mg).
- Soluble in DMSO for assay preparation.
Medchemexpress LLC TLR7/8 agonist 3 | 642473-95-8 | 100.0% | C17H23N5O | 10MG
TLR7/8 agonist 3 is a small-molecule agonist of Toll-like receptors 7 and 8 used for immunology research. Described in patent literature, it is supplied in high purity as a solid and is also available as a DMSO solution for in vitro and in vivo studies. Supplier documents include solubility, formulation, and storage guidance for research applications.
- Potent TLR7 and TLR8 agonist activity
- High purity suitable for research applications
- Available as solid and DMSO solution for flexible dosing
- Documented solubility and in vivo formulation guidance
- Stable long-term storage recommendations for powder form
- Characterized chemical formula and molecular weight
Medchemexpress LLC O-desmethyl midostaurin | 740816-86-8 | 97.1% | 556.61 g/mol | C34H28N4O4 | 5 MG
O-desmethyl midostaurin is the primary active metabolite of the kinase inhibitor midostaurin. Supplied as a solid research reagent, it is intended for in vitro and preclinical research use only and is not for human or clinical use. The compound is characterized by a molecular formula of C34H28N4O4 and a molecular weight of 556.61 g/mol.
- Active metabolite used in metabolism and pharmacology studies.
- Molecular formula C34H28N4O4 and molecular weight 556.61 g/mol.
- Purity 97.1%.
- Off-white to light yellow solid powder.
- Store powder at -20°C for long-term stability; short-term storage at 4°C.
- Stable in solvent at -80°C for up to 6 months.
- For research use only; not intended for human or clinical use.
Medchemexpress LLC Tlr7/8/9-in-1 | 2180127-82-4 | 98.5% | 435.60 g/mol | C27H37N3O2 | 5 MG
TLR7/8/9-IN-1 is a potent, orally bioavailable small-molecule antagonist of Toll-like receptors 7, 8, and 9 used in preclinical studies to inhibit TLR signaling and downstream cytokine release. The compound is supplied as a high-purity solid with published in vitro and in vivo solubility and activity data.
- Potent antagonist activity (IC50 = 43 nM in TLR7/8/9 assays)
- Demonstrates 4.8 nM potency versus TLR7 in PBMC IL-6 reduction
- High reported purity of 98.5%
- Molecular weight 435.60 g/mol; formula C27H37N3O2
- Solid, off-white to light-yellow physical appearance
- Soluble in DMSO (83.33 mg/mL) and formulated for in vivo use (≥2.08 mg/mL)
- Suitable for preclinical studies of TLR pathway modulation