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Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.
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(S)-Bromoenol lactone is a chiral, mechanism-based irreversible inhibitor of calcium-independent phospholipase A2β (iPLA2β) used in biochemical and cellular research to investigate arachidonate release pathways. The compound is supplied at high purity as a solution and is typically stored at -20°C for long-term stability.
Irreversible inhibitor of calcium-independent phospholipase A2β (iPLA2β)
Reported activity: IC50 ≈ 2 μM for vasopressin-induced arachidonate release in A10 cells
Molecular weight 317.18 g/mol; formula C16H13BrO2
Purity 99.1%
Storage: solution at -20°C; stable for about 2 years
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