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Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.
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PHA-665752 is a selective, ATP-competitive inhibitor of the c-Met (HGFR) receptor tyrosine kinase used in preclinical research to induce apoptosis, cause cell-cycle arrest, and reduce tumor growth in vitro and in vivo. It demonstrates high potency and selectivity versus other kinases and is supplied for research use only.
Selective ATP-competitive c-Met inhibitor with Ki ≈ 4 nM and IC50 ≈ 9 nM.
High purity solid (approximately 99.9%) suitable for biochemical assays.
Molecular formula C32H34Cl2N4O4S; molecular weight 641.61 g/mol.
Storage: powder at -20°C for long term; in solution store at -80°C when possible.
Supplied in small preweighed milligram quantities for laboratory research.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More