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Pyrroles

Aromatic organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that forms an amine functional group.

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1

Sigma Aldrich Fine Chemicals Biosciences BQ-788 >=95%, solid | 156161-89-6 | MFCD00797882 | 200UG

BQ-788 >=95%, solid | Purity: >=95% | Mol Wt: 663.78 | 156161-89-6 | MFCD00797882 | 200UG

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2

Enzo Life Sciences ET B receptor antagonist. sodium salt (1mg). CAS: 156161-89-6

Highly potent and selective ETB-receptor antagonist. Alternative name: BQ-788 . Na. Formula: C34H50N5O7Na. MW: 663.7. Purity: ≥95% (HPLC). Formulation: Lyophilized from 0.1M sodium bicarbonate. Solubility: Soluble in methanol (0.5mg/ml), DMSO (4mg/ml), 0.1M sodium bicarbonate (3mg/ml) or 100% ethanol (4mg/ml); insoluble in water. Long Term Storage: -20°C.

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3

Enzo Life Sciences ET B receptor antagonist. sodium salt (0.5mg). CAS: 156161-89-6

Highly potent and selective ETB-receptor antagonist. Alternative name: BQ-788 . Na. Formula: C34H50N5O7Na. MW: 663.7. Purity: ≥95% (HPLC). Appearance: White to off-white powder. Formulation: Lyophilized from 0.1M sodium bicarbonate. Peptide content: 75-95%. Solubility: Soluble in methanol (0.5mg/ml), DMSO (4mg/ml), 0.1M sodium bicarbonate (3mg/ml) or 100% ethanol (4mg/ml); insoluble in water. Long Term Storage: -20°C.

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4

eMolecules​ Medchem Express / BQ-788 (sodium salt) / 1mg / 446266888 / HY-15894 / / 156161-89-6 / MFCD00797882 / 663.792 / C34H50N5NaO7

Medchem Express / BQ-788 (sodium salt) / 1mg / 446266888 / HY-15894 / / 156161-89-6 / MFCD00797882 / 663.792 / C34H50N5NaO7

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5

Apexbio Technology LLC BQ-788 sodium salt(Synonyms: BQ 788 sodium salt, BQ788 sodium, Sodium BQ-788, ET-B receptor antagonist BQ-788), 1mg, CAS: 156161-89-6.
SDP

BQ-788 sodium salt (CAS 156161-89-6) is a selective antagonist targeting endothelin B (ETB) receptors In vitro studies demonstrate that BQ-788 inhibits ET-1 binding to human ETB receptors with an IC50 of approximately 1 2 nM displaying significantly lower affinity for ETA receptors (IC50 1300 nM) Competitive binding assays also confirm potent ETB receptor antagonism in porcine cerebellar membranes and human hGH cells (IC50 0 9-1 2 nM) BQ-788 exhibits minimal activity towards other peptide hormone receptors tested at concentrations up to 10 M Its notable selectivity and potency for ETB receptors make BQ-788 valuable for investigating ET receptor-mediated physiological processes such as bronchoconstriction

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