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Medchemexpress LLC Bi-2852 | 2375482-51-0 | 99.5% | 516.59 g/mol | C31H28N6O2 | 100MG
BI-2852 is a small-molecule inhibitor that targets the KRAS switch I/II pocket for research applications. It binds the SI/II pocket with nanomolar affinity and disrupts GEF, GAP, and effector interactions, leading to inhibition of downstream KRAS signaling and antiproliferative effects in KRAS-mutant cells.
- Purity 99.46%.
- Molecular weight 516.59 g/mol.
- Chemical formula C31H28N6O2.
- Soluble in DMSO (55 mg/mL) for in vitro studies.
- Available as solid and as DMSO solution formats for flexibility in experiments.
- Storage recommendations: 4°C for solid; in solvent -80°C (2 years) or -20°C (1 year) under nitrogen.
