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Filtered Search Results
Medchemexpress LLC Boc-NH-C4-Br | 164365-88-2 | 252.15 | 500 MG
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Boc-NH-C4-Br is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 250mg | 525043584](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000129525.jpg-250.jpg)
eMolecules 120205-50-7 | N-Boc-dolaproine | Ambeed | MFCD18157735 | 287.356 | C14H25NO5 | 95.000 | CO[C@H]([C@@H](C)C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 250mg | 525043584
N-Boc-dolaproine | Ambeed | 120205-50-7 | MFCD18157735 | 287.356 | C14H25NO5 | 95.000 | CO[C@H]([C@@H](C)C(O)=O)[C@@H]1CCCN1C(=O)OC(C)(C)C | 250mg | 525043584
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Medchemexpress LLC Boc-NH-PEG7-propargyl | 2112737-90-1 | >=97.0% | C22H41NO9 | 100 MG
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Boc-NH-PEG7-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
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Medchemexpress LLC Mal-NH-PEG8-Boc | 2864817-39-8 | >98.0% | 648.74 | 500 MG
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Mal-NH-PEG8-Boc is a PEG-based PROTAC linker, a chemical compound with the molecular formula C30H52N2O13 and a molecular weight of 648.74. This linker is designed for use in the synthesis of PROTACs, which are bifunctional molecules that induce the degradation of target proteins. It is generally supplied as an oil with a purity greater than 98%. The product is recommended to be stored at 4°C under nitrogen to maintain its stability.
- Functions as a PROTAC linker
- PEG-based structure enhances solubility
- Chemical formula: C30H52N2O13
- Molecular weight: 648.74
- Purity typically greater than 98%
- Appears as an oil
- Used in the synthesis of PROTACs
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Medchemexpress LLC Carbonic anhydrase 9 protein (canine, recombinant, C-terminal His tag) | 5 UG
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Recombinant canine Carbonic Anhydrase 9 (CA9) produced in HEK293 cells with a C-terminal His tag. CA9 catalyzes the reversible hydration of carbon dioxide to bicarbonate and protons and is commonly used in biochemical and cell-biology research related to pH regulation and tumor biology.
- Recombinant canine origin expressed in HEK293 cells.
- C-terminal His tag enables purification and detection.
- Functionally relevant enzyme for pH regulation and tumor biology studies.
- Suitable for biochemical and cell-based assays.
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Medchemexpress LLC (R,S,S,R,S)-Boc-Dap-NE | 2994330-72-0 | 97.1% | 420.54 | C23H36N2O5 | 10 MG
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(R,S,S,R,S)-Boc-Dap-NE is the inactive stereoisomer of Boc-Dap-NE supplied as a research chemical and synthetic intermediate. It is intended for use as an experimental control and as a building-block intermediate in the synthesis of monomethyl auristatin E; safety documentation and analytical data are provided for research use.
- Inactive stereoisomer suitable as experimental control.
- Serves as intermediate in monomethyl auristatin E synthesis.
- Supplied in a 10 MG quantity for laboratory use.
- Reported purity approximately 97.1%.
- Molecular weight 420.54 g·mol⁻¹; formula C23H36N2O5.
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Medchemexpress LLC (S,S,R,S,R)-Boc-Dap-NE | 3026595-14-9 | >98.0% | 420.54 g/mol | C23H36N2O5 | 10 MG
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(S,S,R,S,R)-Boc-Dap-NE is a Boc-protected diaminopropionic dipeptide isomer used as a drug intermediate in the synthesis of monomethyl auristatin E and related antibody-drug conjugate payloads. Supplied in small research quantities for medicinal chemistry and ADC payload synthesis.
- Drug intermediate suitable for ADC payload synthesis.
- Purity greater than 98.0%.
- Molecular formula C23H36N2O5.
- Molecular weight 420.54 g/mol.
- CAS number 3026595-14-9.
- Soluble in DMSO: 200 mg/mL (ultrasonic); 10 mM in DMSO.
- Available in small research sizes (10 mg, 25 mg, 100 mg).
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Medchemexpress LLC 4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester | 470478-90-1 | 98.5% | C21H33BN2O4 | 500 MG
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This product, 4-(4-Boc-piperazinemethyl)phenylboronic acid pinacol ester, functions as a PROTAC linker, utilized in the synthesis of compounds such as CST905. PROTACs are designed to leverage the intracellular ubiquitin-proteasome system, enabling the selective degradation of target proteins by linking a ligand for an E3 ubiquitin ligase with a ligand for the target protein. This compound appears as a white to light yellow solid and is designated for research purposes only.
- Functions as a PROTAC linker
- Used in the synthesis of CST905
- Exploits ubiquitin-proteasome system for selective protein degradation
- Appears as a white to light yellow solid
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Boc-Met-Leu-Phe-OH | 67247-12-5 | MFCD00037435 | 99.9% | 509.66 | C25H39N3O6S | 25 MG
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Boc-Met-Leu-Phe-OH is a formyl peptide receptor (FPR) antagonist that reduces superoxide production induced by fMLF, with an IC50 of 0.63 μM. It is supplied as a high-purity peptide for research use in studies of FPR signaling and neutrophil activation.
- Reduces fMLF-induced superoxide production (IC50 = 0.63 μM)
- High purity (99.9%)
- Molecular weight 509.66 g/mol
- Molecular formula C25H39N3O6S
- Available in small mg quantities for lab-scale studies
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Medchemexpress LLC (S)-1-Boc-3-methylpiperazine | 147081-29-6 | 100.0% | 200.28 | 5 G
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(S)-1-Boc-3-methylpiperazine is a drug intermediate primarily used for the synthesis of Sotorasib. This product is a solid, typically white to off-white in color. It is intended for research use only and has not been fully validated for medical applications.
- High purity of 99.97%
- Molecular weight of 200.28
- Solid, white to off-white appearance
- Soluble in DMSO at 100 mg/mL
- Recommended storage at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
- Identified by CAS number 147081-29-6
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Medchemexpress LLC Carbamic acid, N-(4-bromobutyl)-, 1,1-dimethylethyl ester | 164365-88-2 | 252.15 | 1 G
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Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. This chemical has a molecular weight of 252.15 and appears as a white to off-white solid below 30°C, becoming a liquid above 32°C. It is designed for research use only.
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Medchemexpress LLC Carbonic anhydrase inhibitor 16 | 4479-70-3 | 98.0% | 302.31 | 100 MG
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Carbonic anhydrase inhibitor 16 (compound 1) is a dengue protease inhibitor with inhibitory activity against carbonic anhydrase hCA I and hCA II (Ki: 28.5 nM, 2.2 nM).
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eMolecules 88950-64-5 | 1-(Boc-Amino)cyclopropanecarboxylic acid | ChemScene | MFCD00083257 | 201.222 | C9H15NO4 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C(O)=O | 5g | 346751343
1-(Boc-Amino)cyclopropanecarboxylic acid | ChemScene | 88950-64-5 | MFCD00083257 | 201.222 | C9H15NO4 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C(O)=O | 5g | 346751343
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eMolecules 138647-49-1 | 1-Boc-4-(trifluoromethanesulfonyloxy)-3,6-dihydro-2H-pyridine | Synthonix - Stock | MFCD09997858 | 331.310 | C11H16F3NO5S | 95.000 | CC(C)(C)OC(=O)N1CCC(OS(=O)(=O)C(F)(F)F)=CC1 | 5g | 525911277
1-Boc-4-(trifluoromethanesulfonyloxy)-3,6-dihydro-2H-pyridine | Synthonix - Stock | 138647-49-1 | MFCD09997858 | 331.310 | C11H16F3NO5S | 95.000 | CC(C)(C)OC(=O)N1CCC(OS(=O)(=O)C(F)(F)F)=CC1 | 5g | 525911277
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Medchemexpress LLC N-boc-peg4-bromide | 1076199-21-7 | MFCD09840081 | 98.0% | 356.25 g/mol | C13H26BrNO5 | 500 MG
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N-boc-peg4-bromide is a Boc-protected PEG4 bromide linker used as a PEG spacer and a reactive alkyl bromide for conjugation chemistry. It is intended for research use in small-molecule conjugation workflows, including PROTAC and cleavable linker synthesis, and has specified solubility and storage recommendations.
- Boc-protected amine with terminal bromide for alkylation.
- Designed as a PEG4 spacer to increase solubility and flexibility.
- Soluble in DMSO; recommended concentration up to 100 mg/mL with ultrasonic assistance.
- Purity ≥98.0% as supplied for research applications.
- Available in multiple pack sizes, including a 500 mg pack.
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