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Filtered Search Results
TARGETMOL CHEMICALS INC Bisindolylmaleimide III 10MG
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Also available in 1 mL, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC), specifically interacting with PKCalpha or ribosomal S6 protein kinase 1 upon activation of these kinases. Purity 98.6%
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Medchemexpress LLC Bisindolylmaleimide IV (Arcyriarubin A) | 119139-23-0 | MFCD00236432 | 99.7% | 327.34 g·mol-1 | C20H13N3O2 | 25 MG
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Bisindolylmaleimide IV (Arcyriarubin A) is a small-molecule research reagent that potently inhibits protein kinase C (PKC) and reduces human cytomegalovirus replication in cell culture. Supplied as a high-purity solid for in vitro assays, prepare solutions in appropriate solvents and follow safety guidance for handling and storage.
- Potent protein kinase C inhibitor with PKC IC50 ≈ 0.1-0.55 μM.
- Inhibits human cytomegalovirus replication (IC50 ≈ 0.2 μM).
- High purity (99.7%) suitable for in vitro research.
- Small-molecule solid; molecular weight 327.34 g·mol-1, formula C20H13N3O2.
- Soluble in DMSO and common organic solvents for assay preparation.
- Intended for research use only; not for human or veterinary use.
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Sigma Aldrich Fine Chemicals Biosciences 3-Maleimidopropionic acid N-hydroxysuccinimide ester 99% | 55750-62-4 | MFCD00043141 | 25MG
3-Maleimidopropionic acid N-hydroxysuccinimide ester 99% | Purity: 99% | Mol Wt: 266.21 | 55750-62-4 | MFCD00043141 | 25MG
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Medchemexpress LLC N-(hydroxymethyl)acetamide | 625-51-4 | MFCD00014417 | 96.5% | 89.09 g·mol-1 | C3H7NO2 | 25 G
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N-(Hydroxymethyl)acetamide is a small organic compound (C3H7NO2, MW 89.09 g·mol-1) used as a reagent and model molecule in biochemical and physical chemistry research. It is suitable for studies of hydrogen bonding, dimerization, mechanistic investigations, and small-scale synthetic applications.
- High purity (96.5%).
- Low molecular weight and simple structure for model studies.
- Soluble in common organic solvents and water.
- Useful for hydrogen-bonding and dimerization investigations.
- Available in laboratory-scale quantities for research use.
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eMolecules 2-Boc-2-Azabicyclo[2.2.1]hept-5-ene | 188345-71-3 | MFCD22416354 | 1g
Ambeed | 2-Boc-2-Azabicyclo[2.2.1]hept-5-ene | 1g | 491166218 | A101562 | | 188345-71-3 | MFCD22416354 | 195.262 | C11H17NO2
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Accela Chembio Inc (s)-(+)-5-(hydroxymethyl)-2-pyrrolidinone | 25g | 17342-08-4 | MFCD00077792 | 98% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/n2
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(s)-(+)-5-(hydroxymethyl)-2-pyrrolidinone | 25g | 17342-08-4 | MFCD00077792 | 98% | Shelf Life: 1260 Days | Light Sensitive/moisture Sensitive/n2
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eMolecules 6-(Hydroxymethyl)picolinonitrile | 50501-38-7 | MFCD07367926 | 5g
Ambeed | 6-(Hydroxymethyl)picolinonitrile | 5g | 588342564 | A399368 | | 50501-38-7 | MFCD07367926 | 134.138 | C7H6N2O
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eMolecules N-(Nitrosomethyl)ethanolamine | 26921-68-6 | MFCD01727814 | 250mg
Toronto Research Chemicals | N-(Nitrosomethyl)ethanolamine | 250mg | 601599270 | N589055 | | 26921-68-6 | MFCD01727814 | 104.109 | C3H8N2O2
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eMolecules Azide-PEG8-Alcohol | 352439-36-2 | MFCD08274607 | 5g
Broadpharm | Azide-PEG8-Alcohol | 5g | 309209143 | BP-21075 | 98.000 | 352439-36-2 | MFCD08274607 | 395.453 | C16H33N3O8
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eMolecules N-Succinimidyl-S-acetylthioacetate | 76931-93-6 | MFCD00036891 | 250mg
Chem-Impex | N-Succinimidyl-S-acetylthioacetate | 250mg | 272386928 | 23028 | | 76931-93-6 | MFCD00036891 | 231.220 | C8H9NO5S
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Apexbio Technology LLC GW311616 hydrochloride 197890-44-1 5mg
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GW311616 hydrochloride (CAS 197890-44-1) is a selective cell-permeable inhibitor of human neutrophil elastase (HNE) exhibiting an IC50 of 22 nM and a Ki of 0 13 nM in enzymatic assays It demonstrates pronounced selectivity with IC50 values exceeding 100 M for trypsin cathepsin G and plasmin and greater than 3 M for chymotrypsin and tissue plasminogen activator In human whole blood assays GW311616 hydrochloride achieves an IC50 of 0 67 M The compound is orally bioavailable and displays prolonged activity in dog blood samples indicating a sustained inhibitory effect on neutrophil elastase GW311616 hydrochloride is valuable for investigating HNE s role in inflammation and related pathologies
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Selleck Chemical LLC Rolipram ZK-62711-10mg
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The PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent.
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Medchemexpress LLC 1-(2,5-dioxopyrrolidin-1-yl)oxy-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid | 1193111-39-5 | MFCD20227457 | 92.1% | 406.45 | C13H14N2O7S3 | 25 MG
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sulfo-SPDB is a cleavable antibody-drug conjugate (ADC) linker featuring a pyridyldisulfide-based disulfide that is reductively cleavable and a sulfonic acid moiety to improve solubility. It is supplied for research use and is designed for preparing linker-drug intermediates and conjugation to antibodies under controlled, reducing conditions.
- Cleavable disulfide linker enabling reductive release of payload.
- Sulfonic acid group improves aqueous solubility.
- High solubility in DMSO (≥125 mg/mL) for formulation flexibility.
- Compatible with standard ADC conjugation workflows.
- Requires cold storage and protection from light for stability.
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Medchemexpress LLC Rac cotinine-d4 | 350818-68-7 | 99.6% | 180.24 | C10H8D4N2O | 10 MG
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(Rac)-Cotinine-d4 is the deuterium-labeled racemic form of cotinine intended for use as an analytical tracer and internal standard in quantitative assays (LC-MS, GC-MS, and NMR). It is supplied in small milligram quantities for research and method development.
- Deuterium-labeled racemic cotinine (d4) for use as an internal standard.
- Suitable for LC-MS, GC-MS, and NMR quantitation.
- High purity (~99.6%) to minimize interference in analytical assays.
- Provided in small, ready-to-use milligram quantities for analytical workflows.
- Stable when stored under recommended temperature conditions for reliable performance.
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Medchemexpress LLC 4-(Hydroxymethyl)phenylacetic acid | 73401-74-8 | 166.18 | 10 G
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4-(Hydroxymethyl)phenylacetic acid (4HMPAA) is a compound that functions as the primary structural component for insoluble polypeptides. It can participate in chemical reactions with DEPBT and 4-acetylaniline to generate amide intermediates. This compound is also recognized as a metabolite resulting from the breakdown of flavonoids, like quercetin, by colonic microbiota. Furthermore, 4HMPAA significantly inhibits 6-MP oxidation, demonstrating a selective inhibitory action as it does not considerably affect xanthine oxidation.
- Functions as the main body of insoluble polypeptides.
- Reacts with DEPBT and 4-acetylaniline to form amide intermediates.
- A metabolite derived from the metabolism of flavonoids such as quercetin by colonic microbiota.
- Exhibits significant inhibition of 6-MP oxidation.
- Shows no significant inhibition on xanthine oxidation.
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