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Filtered Search Results
Medchemexpress LLC Bisindolylmaleimide VIII acetate | 138516-31-1 | 99.7% | 25 MG
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Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor, with an IC50 of 158 nM for rat brain PKC. It specifically inhibits various PKC isoforms including PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε. This compound facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases. It is supplied as a brown to reddish-brown solid with a molecular weight of 458.51 and chemical formula C26H26N4O4. This product is for research use only.
- Potent and selective protein kinase C (PKC) inhibitor
- Inhibits PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-ε isoforms
- Facilitates Fas-mediated apoptosis
- Inhibits T cell-mediated autoimmune diseases
- High purity of 99.7%
- Supplied as a solid with a brown to reddish-brown color
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Medchemexpress LLC Br-PEG3-C2-Boc | 782475-37-0 | 98.0% | 250 MG
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Br-PEG3-C2-Boc is a PEG-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). PROTACs are compounds that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein via a linker.
- PEG-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC 2,5-dioxo-1-pyrrolidinyl 11-azidoundecanoate | 850080-13-6 | MFCD29041759 | 98.0% | 324.38 g/mol | C15H24N4O4 | 1 G
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2,5-Dioxo-1-pyrrolidinyl 11-azidoundecanoate is an azide-containing N-hydroxysuccinimide (NHS) ester linker for bioconjugation. It provides an activated carboxylate for efficient coupling to primary amines and a terminal azide for copper-catalyzed or strain-promoted azide-alkyne cycloaddition. Typical applications include linker synthesis, protein and peptide labeling, and assembly of multifunctional conjugates.
- Activated NHS ester for efficient amine coupling
- Terminal azide for click-chemistry conjugation
- High purity (98.0% by NMR)
- Chemical formula C15H24N4O4, MW 324.38 g/mol
- Available as a solid; common package 1 G
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Aobchem AOBCHEM
5000993596 2 3-DIFLUOROPHENYL PYRROLIDI
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Medchemexpress LLC (Rac)-Modipafant | 122956-68-7 | 98.15% | 605.09 | 50 MG
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(Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist that prevents dengue infection. This product is for research use only.
- Orally active.
- Selective.
- Long-acting irreversible platelet activating factor receptor (PAFR) antagonist.
- Prevents dengue infection.
- Exhibits highly selective, time-dependent inhibition of PAF-induced aggregation of rabbit washed platelets.
- Dose-dependently inhibits zymosan-induced articular hyperalgesia.
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Medchemexpress LLC O-proparagyl-N-boc-ethanolamine | 634926-63-9 | MFCD22418470 | >95.0% | 199.25 | C10H17NO3 | 1 G
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O-Proparagyl-N-Boc-ethanolamine is a Boc-protected propargyl ethanolamine used as a click-chemistry crosslinker and synthetic building block for bioconjugation and small-molecule synthesis. It features a terminal alkyne for azide coupling and a t-Boc protected amine that can be removed under mild acidic conditions. For research use only.
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Aobchem AOBCHEM
5000995362 4- 1- TERT-BUTOXYCARBONYL PIPE
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eMolecules 286961-14-6 | N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | MFCD03840345 | 309.210 | C16H28BNO4 | 98.000 | CC(C)(C)OC(=O)N1CCC(=CC1)B1OC(C)(C)C(C)(C)O1 | 5g | 445405937
N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | 286961-14-6 | MFCD03840345 | 309.210 | C16H28BNO4 | 98.000 | CC(C)(C)OC(=O)N1CCC(=CC1)B1OC(C)(C)C(C)(C)O1 | 5g | 445405937
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C(O)=O | 1g | 112238539](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000492322.jpg-250.jpg)
eMolecules 868689-63-8 | (S)-N-Boc-2-morpholinecarboxylic acid | Advanced ChemBlocks | MFCD06200662 | 231.248 | C10H17NO5 | 95.000 | CC(C)(C)OC(=O)N1CCO[C@@H](C1)C(O)=O | 1g | 112238539
(S)-N-Boc-2-morpholinecarboxylic acid | Advanced ChemBlocks | 868689-63-8 | MFCD06200662 | 231.248 | C10H17NO5 | 95.000 | CC(C)(C)OC(=O)N1CCO[C@@H](C1)C(O)=O | 1g | 112238539
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STA PHARMACEUTICAL US LLC DNA C(Bz) amidite | 1 g | CAS 102212-98-6 | MDL MFCD00036315
DNA C(Bz) amidite is a Amidite reagent (Subcategory: Cytosine Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 102212-98-6
- MDL: MFCD00036315
- InChIKey: PGTNFMKLGRFZDX-SALLYJDFSA-N
- Molecular Weight: 833.922761998
- Molecular Formula: C46H52N5O8P
- Purity: ≥99%
- Container Type: 60 mL Glass (20-400)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 63 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1C[C@H](N2C(N=C(C=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)OCCC#N)C(C)C)C
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Apexbio Technology LLC Z-VEID-FMK 210344-96-0 10mg
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Z-VEID-FMK is a cell-permeable irreversible inhibitor primarily targeting caspase-6 a cysteine protease involved in apoptosis regulation This peptide-based fluoromethyl ketone derivative specifically binds to the active site of caspase-6 blocking the proteolytic cleavage events mediated by this enzyme In apoptosis signaling caspase-6 activation contributes to downstream cleavage of multiple cellular substrates including lamins and nuclear proteins In various experimental models Z-VEID-FMK has been employed to dissect caspase-6-dependent apoptotic pathways and to analyze caspase-specific roles in neuronal and immune cell apoptosis induced by stimuli such as TNF or Fas ligand
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eMolecules 144043-18-5 | (R)-N-methylpyrrolidin-3-amine dihydrochloride | MFCD09955426 | 250mg
Medchem Express | LKY-047 | 5mg | 721611063 | HY-117026 | 1954681-29-8 | 421.405 | C23H19NO7
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Medchemexpress LLC Bisindolylmaleimide I | 133052-90-1 | MFCD00236428 | 98.2% | 412.48 | 100 MG
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Bisindolylmaleimide I is a cell-permeable and reversible protein kinase C (PKC) inhibitor. It exhibits inhibitory activity against various PKC isoforms, including PKCα, PKCβI, PKCβII, and PKCγ. This compound also functions as a GSK-3 inhibitor, making it suitable for a range of research applications.
- Cell-permeable and reversible PKC inhibitor
- Inhibits PKCα with an IC50 of 20 nM
- Inhibits PKCβI with an IC50 of 17 nM
- Inhibits PKCβII with an IC50 of 16 nM
- Inhibits PKCγ with an IC50 of 20 nM
- Functions as a GSK-3 inhibitor
- Protects against *Bacillus anthracis* lethal toxin-mediated cytotoxicity
- Inhibits exosome and microvesicle release from PC3 cells
- Enhances cytotoxicity of 5-fluorouracil
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![eMolecules 1210344-83-4 | Ertugliflozin L-pyroglutamic acid | Ambeed566.000 | C27H32ClNO10 | 99.000 | OC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1 | 1mg | 682927823](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502424877.JPG-250.jpg)
eMolecules 1210344-83-4 | Ertugliflozin L-pyroglutamic acid | Ambeed566.000 | C27H32ClNO10 | 99.000 | OC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1 | 1mg | 682927823
Ertugliflozin L-pyroglutamic acid | Ambeed | 1210344-83-4566.000 | C27H32ClNO10 | 99.000 | OC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1 | 1mg | 682927823
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Chemscene CHEMSCENE
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5000579265 N-TERT-BUTOXYCARBONYL-N-ME 10G
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