Pyrrolidines

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.

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631 – 645 of 4,577 results

631

Medchemexpress LLC (Z)-semaxanib | 194413-58-6 | MFCD09763655 | 238.29 g/mol | C15H14N2O | 25 MG

(Z)-Semaxanib is a small-molecule tyrosine kinase inhibitor supplied for research use as a light yellow to yellow solid. It shows cytotoxic activity against TAMH and HepG2 cell lines (IC50 6.28 μM and 8.17 μM, respectively) and is soluble in DMSO.

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632

eMolecules 1-N-Cbz-nipecotamide | 569348-14-7 | MFCD04115335 | 1g

Combi-Blocks, Inc. | 1-N-Cbz-nipecotamide | 1g | 569298178 | ST-8435 | 97.000 | 569348-14-7 | MFCD04115335 | 262.309 | C14H18N2O3

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633

eMolecules 2-(Cbz-amino)propanamide | 2503-29-9 | MFCD00136699 | 1g

Combi-Blocks | 2-(Cbz-amino)propanamide | 1g | 350782974 | QN-7330 | 96.000 | 2503-29-9 | MFCD00136699 | 222.244 | C11H14N2O3

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634

Cayman Chemical 3 Z 6 Z 9 Z 12 Z 15 ZOctadeca

A microalgal PUFA; has been used as a chemotaxonomic biomarker for microalgae and dinoflagellates

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635

Cayman Chemical 9 Z 12 Z 15 Z 18 Z 21 ZTetrac

A very long-chain polyunsaturated fatty acid; has been used to study the desaturation and elongation of ω-3 polyunsaturated fatty acids; found at low levels in mouse brain and spleen and levels decrease in the brain and spleen of old and exceptionally old mice

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636

Medchemexpress LLC (E/Z)-Sib-1893 | 6266-99-5 | 99.8% | 195.26 g/mol | C14H13N | 100 MG

(E/Z)-SIB-1893 is the racemic mixture of the (E)- and (Z)-isomers of SIB-1893, a selective non-competitive antagonist of metabotropic glutamate receptor subtype 5 (mGluR5) used as a research tool in neuroscience and pharmacology. Supplied as a solid powder and as a ready-to-use 10 mM solution in DMSO.

Racemic mixture of (E)- and (Z)-isomers
Selective non-competitive mGluR5 antagonist for research applications
CAS number 6266-99-5
Molecular formula C14H13N; molecular weight 195.26 g/mol
High purity (99.8% assay)
Available as solid powder and 10 mM solution in DMSO
Common pack size: 100 mg; larger sizes available by request

Pricing & Availability

637

Medchemexpress LLC 5H-dibenzo[a,d]cyclohepten-10-ol, 10,11-dihydro-5-[3-(methylamino)propylidene]-d3, (5Z)- | 47132-19-4 | 99.0% | 282.40 g/mol | C19H18D3NO | 100 UG

(Z)-10-Hydroxynortriptyline-d3 is the deuterium-labeled isotopic analogue of the nortriptyline metabolite (Z)-10-hydroxynortriptyline, provided as a high-purity analytical standard for metabolite identification, quantitative LC-MS/MS assays, and pharmacokinetic studies.

Deuterium-labeled internal standard suitable for LC-MS/MS quantification.
High purity supporting accurate quantitative analysis and low background.
Supplied in microgram-scale packaging for trace-level analytical workflows.
Chemical formula C19H18D3NO and molecular weight 282.40 g/mol aid method setup.
Stability and handling information provided in accompanying COA and SDS.

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638

Medchemexpress LLC (Z,E)-9,12-tetradecadienol | 42521-46-0 | 95.0% | 210.36 | C14H26O | 50mg

(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]

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639

Medchemexpress LLC (E/Z)-demethoxycurcumin (p-hydroxycinnamoyl-feruloylmethane) | 24939-17-1 | 98.0% | 338.35 g·mol⁻¹ | C20H18O5 | 10 MG

(E/Z)-Demethoxycurcumin is a curcuminoid isolated from Curcuma species, described as having anticoagulative activity. Supplied as a high-purity solid for research use, it is suitable for biochemical, pharmacological, and antioxidant studies.

High purity suitable for research applications.
Curcuminoid with reported anticoagulative activity.
Applicable to anti-inflammatory and antioxidant studies.
Solid form; store at 4°C and protect from light.
Provided in small-scale quantities for laboratory experiments.

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640

Cayman Chemical 9 Z 11 E 13 EOctadecatrienoic

A fatty acid agonist of PPARγ; activates PPARγ transcriptional activity in a reporter assay using RAW 264.7 cells at 10 µM; an inhibitor of DNA polymerase α, -β, -γ, -Δ, and -ε (IC50s = 10.7, 13.4, 10.6, 14, and 22 µM, respectively); an inhibitor of topoisomerase I and -II (IC50s = 20 and 5 µM, respectively); reduces the viability of, and induces apoptosis in, MCF-7 breast cancer cells in a concentration-dependent manner; induces ferroptosis in MDA-MB-231 breast cancer cells in an ACSL1-dependent manner; reduces clinical signs of disease in a model of DSS-induced IBD in PPARγ-expressing, but not PPARγ-knockout, mice

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641

Apexbio Technology LLC Z-Guggulsterone 39025-23-5 50mg

Z-Guggulsterone (CAS 39025-23-5) is a small-molecule antagonist targeting multiple steroid hormone receptors including glucocorticoid (IC50 1740 nM) mineralocorticoid (IC50 1000 nM) androgen (IC50 220 nM) progesterone (EC50 1200 nM) estrogen (EC50 5000 nM) and farnesoid X (IC50 50000 nM) receptors It is designed to modulate these targets thereby influencing steroid receptor-mediated signaling pathways Z-Guggulsterone exerts its biological activity primarily through inhibition of receptor-mediated angiogenic processes In cell-based studies Z-Guggulsterone demonstrates dose- and time-dependent inhibition of cellular migration and tube formation in DU145 prostate cancer cells and human umbilical vein endothelial cells (HUVEC) Based on these pharmacological properties Z-Guggulsterone holds research potential in studies of tumor-associated angiogenesis and steroid receptor signaling

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642

Medchemexpress LLC (Z,E)-tetradeca-9,12-dien-1-ol | 42521-46-0 | 95.0% | 210.36 g/mol | C14H26O | 1g

(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]

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643

Cayman Chemical 7 S 17 Sdihydroxy8 E 10 Z 13

A specialized pro-resolving mediator; induces activation of GPR101, GPR32, and GPR18 in β-arrestin recruitment assays using CHO cells expressing the human receptors (EC50s = 4.6, 14, and 1.5 pM, respectively); increases efferocytosis of apoptotic HL-60 cells and phagocytosis of S. aureus bioparticles by isolated human monocyte-derived macrophages at 1 nM; prevents weight loss and decreases disease severity and hind paw edema in a K/BxN serum transfer-induced mouse model of inflammatory arthritis at 150 ng/animal; decreases blood leukocyte activation and aortic lesions in ApoE-/- mice fed a western diet; plasma levels are increased in patients with PDAC

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644

Medchemexpress LLC Gamma-secretase inhibitor I | 133407-83-7 | 97.6% | 50 MG

Z-LLNle-CHO (Z-Leu-Leu-Nle-CHO) is a peptide aldehyde gamma-secretase inhibitor used in biochemical and cell-based research. It blocks Akt-mediated pro-survival signaling and has been reported to induce caspase- and ROS-dependent apoptosis, making it useful for cancer research applications.

Gamma-secretase inhibitor for biochemical and cellular assays.
Induces caspase- and ROS-dependent apoptosis by blocking Akt signaling.
Used in cancer research models, including breast cancer and leukemia.
High purity suitable for research use (~97.6%).
Molecular formula C26H41N3O5; molecular weight 475.62 g/mol.
Supplied as a 50 MG pack for laboratory use.

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645

Medchemexpress LLC E/Z-mirin | 299953-00-7 | 99.2% | 220.25 g/mol | C10H8N2O2S | 1 ML

E/Z-Mirin is a stereoisomeric mixture of (E)- and (Z)-mirin that inhibits the MRN (Mre11-Rad50-Nbs1) complex and prevents MRN-dependent ATM activation, used in research on DNA damage response and cell cycle signaling.

Inhibits MRN complex and blocks MRN-dependent ATM activation
Supplied as a 10 mM solution in DMSO and as solid quantities for flexible dosing
High purity suitable for biochemical and cell-based assays
Low molecular weight (220.25 g/mol) facilitates cellular studies
SMILES provided for cheminformatics and compound registries

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Pyrrolidines

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Medchemexpress LLC (Z)-semaxanib | 194413-58-6 | MFCD09763655 | 238.29 g/mol | C15H14N2O | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E/Z)-Sib-1893 | 6266-99-5 | 99.8% | 195.26 g/mol | C14H13N | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5H-dibenzo[a,d]cyclohepten-10-ol, 10,11-dihydro-5-[3-(methylamino)propylidene]-d3, (5Z)- | 47132-19-4 | 99.0% | 282.40 g/mol | C19H18D3NO | 100 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Z,E)-9,12-tetradecadienol | 42521-46-0 | 95.0% | 210.36 | C14H26O | 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E/Z)-demethoxycurcumin (p-hydroxycinnamoyl-feruloylmethane) | 24939-17-1 | 98.0% | 338.35 g·mol⁻¹ | C20H18O5 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Z-Guggulsterone 39025-23-5 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Z,E)-tetradeca-9,12-dien-1-ol | 42521-46-0 | 95.0% | 210.36 g/mol | C14H26O | 1g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gamma-secretase inhibitor I | 133407-83-7 | 97.6% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC E/Z-mirin | 299953-00-7 | 99.2% | 220.25 g/mol | C10H8N2O2S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More