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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Z VAD FMK solid2MG
Z-VAD-FMK inhibits yeast and mammalian peptide N-glycanase (PNGase). It induces apoptosis. Z-VAD-FMK might be associated with endoplasmic reticulum (ER) stress.
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eMolecules EMOLECULES INC
5000841222 S---1-BOC-3-AMINOPYRRO 5G
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Apexbio Technology LLC Z-VDVAD-FMK 210344-92-6 10mg
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Z-VDVAD-FMK (CAS 210344-92-6) is an irreversible cell-permeable inhibitor primarily targeting caspase-2 with additional inhibitory effects on caspases-3 and -7 It functions by binding covalently to the active site of caspase enzymes thereby interrupting downstream apoptotic signaling processes In cellular studies treatment with Z-VDVAD-FMK suppresses caspase-2-dependent cytochrome c release triggered by apoptotic inducers such as etoposide Moreover Z-VDVAD-FMK effectively reduces apoptosis-related responses including cellular detachment DNA fragmentation and cleavage of PARP2 in endothelial cells exposed to oxyhemoglobin This small molecule serves as a pivotal tool for dissecting caspase pathways and investigating apoptosis-mediated cellular outcomes in biomedical research
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AdipoGen Bisindolylmaleimide IV
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Chemical. CAS 119139-23-0. Formula C20H13N3O2. MW 327.3. Cell permeable protein kinase C PKC inhibitor. Inhibits also protein kinase A PKA.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000771776 4-1-BOC-4-PIPERIDYL 5G
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Sigma Aldrich Fine Chemicals Biosciences CETP Activity Assay Kit Su
Cholesteryl ester transfer protein (CETP) is present in normal human plasma. The protein transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway. The method is useful for measuring CETP activity in plasma or serum in all species that express CETP.
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Aobchem AOBCHEM
5001078300 2 6-DIFLUORO-4- PYRROLIDIN-1-Y
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Medchemexpress LLC PROTAC MDM2 Degrader-2 | 2249944-99-6 | 95.0% | 10 MG
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PROTAC MDM2 Degrader-2 is an MDM2 PROTAC degrader that induces the self-ubiquitination and degradation of MDM2, leading to the upregulation of p53 protein. It exhibits anti-tumor activity and is used in cancer research.
- Induces self-ubiquitination and degradation of MDM2
- Upregulates p53 protein
- Exhibits anti-tumor activity
- Used in cancer research
- Inhibits MDM2 protein in A549 cells
- Increases p53 in A549 cells
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Medchemexpress LLC PROTAC CRBN Degrader-1 | 2358775-70-7 | 98.8% | 50 MG
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PROTAC CRBN Degrader-1 (Compound 14a) is a VHL-CRBN heterodimerization PROTAC degrader designed to achieve selective degradation of CRBN by binding two E3 ubiquitin ligases (VHL and CRBN) to each other.
- Achieves selective degradation of CRBN
- Binds two E3 ubiquitin ligases (VHL and CRBN) to each other
- Exhibits rapid degradation of CRBN (DC50=200 nM) in HeLa cells
- Shows relatively weak degrading activity against VHL proteins
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Medchemexpress LLC (Z,E)-9,12-tetradecadienol | 42521-46-0 | 210.36 g/mol | C14H26O | 25mg
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(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]
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Aobchem AOBCHEM
5000977279 2-FLUORO-6-PYRROLIDIN-1-YLPYRI
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Aobchem AOBCHEM
5001077282 6- PYRROLIDIN-1-YL PYRIDIN-3-O
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Medchemexpress LLC 1-Methylpyrrolidine | 120-94-5 | >=95.0% | 1 G
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1-Methylpyrrolidine is an analytical standard intended for research and analytical applications. This methylated pyrrolidine can be used as a precursor to synthesize polyfluorinated pyrrolidine derivatives.
- Used in qualitative, quantitative, and methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
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Apexbio Technology LLC Z-WEHD-FMK(Synonyms: Z-WEHD fluoromethyl ketone, Z-WEHD-FMK inhibitor, Caspase-5 inhibitor Z-WEHD-FMK), 5mg, CAS: 210345-00-9.
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Z-WEHD-FMK (CAS 210345-00-9) is a peptide-based inhibitor primarily targeting inflammatory caspases including caspase-1 -4 and -5 It irreversibly blocks caspase-mediated proteolytic cleavage interfering with cellular signaling pathways involved in inflammation and apoptosis Studies demonstrate that Z-WEHD-FMK treatment prevents Chlamydia-induced fragmentation of the Golgi apparatus by inhibiting golgin-84 cleavage thereby decreasing bacterial proliferation and altering lipid trafficking to pathogen-containing inclusions This inhibitor is frequently utilized in cell biology and infectious disease research to investigate caspase-related cellular processes and microbial pathogenesis mechanisms
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![eMolecules 33305-75-8 | H-Pro-OEt HCl | Ambeed | MFCD00191004 | 179.640 | C7H14ClNO2 | 95.000 | Cl.CCOC(=O)[C@@H]1CCCN1 | 1g | 595927195](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502419680.JPG-250.jpg)
eMolecules 33305-75-8 | H-Pro-OEt HCl | Ambeed | MFCD00191004 | 179.640 | C7H14ClNO2 | 95.000 | Cl.CCOC(=O)[C@@H]1CCCN1 | 1g | 595927195
H-Pro-OEt HCl | Ambeed | 33305-75-8 | MFCD00191004 | 179.640 | C7H14ClNO2 | 95.000 | Cl.CCOC(=O)[C@@H]1CCCN1 | 1g | 595927195
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