Pyrrolidines

Organic heterocyclic compounds that consist of a five-membered ring with four carbon atoms and one nitrogen atom that form a cyclic secondary amine.

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1,171 – 1,185 of 6,304 results

1,171

eMolecules 10595-72-9 | Ditridecyl 3,3'-thiodipropionate | Combi-Blocks, Inc. | MFCD00048453 | 542.900 | C32H62O4S | 95.000 | CCCCCCCCCCCCCOC(=O)CCSCCC(=O)OCCCCCCCCCCCCC | 5g | 818534058

Ditridecyl 3,3'-thiodipropionate | Combi-Blocks, Inc. | 10595-72-9 | MFCD00048453 | 542.900 | C32H62O4S | 95.000 | CCCCCCCCCCCCCOC(=O)CCSCCC(=O)OCCCCCCCCCCCCC | 5g | 818534058

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1,172

Medchemexpress LLC 1- Cbz-amino cyclope 10g

1-(Cbz-amino)cyclopentanecarboxylic acid (Cbz-cycloleucine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research

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1,173

Medchemexpress LLC (Z,E)-9,12-tetradecadien-1-ol | 42521-46-0 | MFCD00270832 | >95.0% | 210.36 g/mol | C14H26O | 1mL

(Z E)-9 12-Tetradecadienol is a synthetic enhancer of male Ephestia cautella attraction[1]

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1,174

Cayman Chemical 9 Z 11 E 13 EOctadecatrienoic

A fatty acid agonist of PPARγ; activates PPARγ transcriptional activity in a reporter assay using RAW 264.7 cells at 10 µM; an inhibitor of DNA polymerase α, -β, -γ, -Δ, and -ε (IC50s = 10.7, 13.4, 10.6, 14, and 22 µM, respectively); an inhibitor of topoisomerase I and -II (IC50s = 20 and 5 µM, respectively); reduces the viability of, and induces apoptosis in, MCF-7 breast cancer cells in a concentration-dependent manner; induces ferroptosis in MDA-MB-231 breast cancer cells in an ACSL1-dependent manner; reduces clinical signs of disease in a model of DSS-induced IBD in PPARγ-expressing, but not PPARγ-knockout, mice

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1,175

Medchemexpress LLC 1- Cbz-amino cyclope 100g

1-(Cbz-amino)cyclopentanecarboxylic acid (Cbz-cycloleucine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research

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1,176

Apexbio Technology LLC Z-WEHD-FMK(Synonyms: Z-WEHD fluoromethyl ketone, Z-WEHD-FMK inhibitor, Caspase-5 inhibitor Z-WEHD-FMK), 5mg, CAS: 210345-00-9.

Z-WEHD-FMK (CAS 210345-00-9) is a peptide-based inhibitor primarily targeting inflammatory caspases including caspase-1 -4 and -5 It irreversibly blocks caspase-mediated proteolytic cleavage interfering with cellular signaling pathways involved in inflammation and apoptosis Studies demonstrate that Z-WEHD-FMK treatment prevents Chlamydia-induced fragmentation of the Golgi apparatus by inhibiting golgin-84 cleavage thereby decreasing bacterial proliferation and altering lipid trafficking to pathogen-containing inclusions This inhibitor is frequently utilized in cell biology and infectious disease research to investigate caspase-related cellular processes and microbial pathogenesis mechanisms

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1,177

Medchemexpress LLC Cbz-NH-PEG4-C2-acid | 756526-00-8 | MFCD11041139 | 95.0% | 399.44 g/mol | C19H29NO8 | 250 MG

Cbz-NH-PEG4-C2-acid is a PEG-based linker designed for PROTAC synthesis. It features a Cbz-protected amino group and a terminal carboxylic acid separated by a four-unit ethylene glycol spacer, providing solubility and flexibility for conjugation. The compound is intended for use in medicinal chemistry to connect ligands and enable targeted protein degrader construction.

Cbz-protected amino group for selective deprotection
Terminal carboxylic acid enables standard amide-coupling chemistries
PEG4 spacer imparts flexibility and improves solubility
Suitable for PROTAC linker construction and linker optimization studies
Available in common laboratory pack sizes for synthesis workflows

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1,178

STA Pharmaceutical DNA C(Bz) amidite | 5 g | CAS 102212-98-6 | MDL MFCD00036315

DNA C(Bz) amidite is a Amidite reagent (Subcategory: Cytosine Series) sold by WuXi TIDES. Offered in 5 g. Store at -20 °C. SDS available for reference.

Specifications
- CAS: 102212-98-6
- MDL: MFCD00036315
- InChIKey: PGTNFMKLGRFZDX-SALLYJDFSA-N
- Molecular Weight: 833.922761998
- Molecular Formula: C46H52N5O8P
- Purity: ≥99%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1C[C@H](N2C(N=C(C=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)OCCC#N)C(C)C)C

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1,179

Medchemexpress LLC (Z)-10-hydroxynortriptyline-d3 | 47132-19-4 | 99.0% | 282.40 | C19H18D3NO | 5 MG

Deuterium-labeled (Z)-10-hydroxynortriptyline-d3 is a stable isotope internal standard of 10-hydroxynortriptyline, provided as a high-purity analytical reagent for use as a tracer and quantitative reference in research applications. It is intended for analytical workflows requiring precise quantitation of metabolites and drug substances.

Stable isotope internal standard for accurate quantitation.
Compatible with NMR, GC-MS, and LC-MS analytical methods.
High purity suitable for analytical assays and calibration.
Available in small research quantities for method development.
Useful as an internal standard or tracer in pharmacokinetic studies.

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1,180

Medchemexpress LLC Z-Leu-Leu-Nle-CHO | 133407-83-7 | 97.6% | 5 MG

Z-LLNle-CHO (Z-Leu-Leu-Nle-CHO) is a peptide aldehyde research reagent used as a γ-secretase inhibitor in biochemical and cell biology studies. It inhibits γ-secretase activity and has been reported to induce caspase- and ROS-dependent apoptosis by interfering with Akt-mediated survival pathways. The compound is supplied in small milligram quantities for laboratory research and assay preparation.

Peptide aldehyde inhibitor of γ-secretase
Used to study apoptosis and Akt signaling pathways
High purity suitable for research applications
Multiple small milligram package sizes available
Soluble in common organic solvents for assay preparation

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1,181

Medchemexpress LLC Nikkomycin Z | 59456-70-1 | 98.6% | 495.44 | 1 MG

Nikkomycin Z is an orally active nucleoside peptide antifungal agent. It functions by inhibiting chitin synthesis, acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. This compound demonstrates antifungal activity and enhances efficacy when combined with echinocandins such as Caspofungin and Micafungin. In vivo studies show it reduces fungal burden and extends survival in murine models of *Histoplasma capsulatum* infection.

Inhibits chitin synthesis
Competitive analogue of UDP-N-acetylglucosamine
Active against *Candida albicans* and *Candida parapsilosis*
Enhances efficacy with echinocandins
Reduces fungal burden in *Histoplasma capsulatum* infection models

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1,182

Medchemexpress LLC Z-LLY-FMK | 133410-84-1 | 98.7% | 557.65 g/mol | C30H40FN3O6 | 5 MG

Z-LLY-FMK (Calpain Inhibitor IV) is a cell-permeable, irreversible peptide-based inhibitor of calpain proteases used in research to investigate apoptosis and parasite infection models. It is supplied as a solid powder with high reported purity and characterized chemical properties for laboratory use.

Irreversible inhibitor of calpain proteases, useful for apoptosis studies.
Cell-permeable peptide suitable for in vitro and in vivo research.
High purity (~98.7%) for reliable experimental results.
White to off-white solid with good solubility in common organic solvents.
Stability information provided for powder and solution storage.

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1,183

Medchemexpress LLC (E/Z)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide | 134036-52-5 | MFCD00236452 | 99.7% | 294.30 g/mol | C17H14N2O3 | 10 MG

(E/Z)-AG490 is the racemic mixture of the (E) and (Z) isomers of AG490, a small-molecule tyrosine kinase inhibitor used in research to probe EGFR and JAK/STAT signaling. It is supplied as a high-purity solid and is commonly prepared as a DMSO solution for cellular and biochemical assays.

Racemic mixture of (E) and (Z) isomers for comparative signaling studies.
Inhibits EGFR, JAK2/3, and STAT3 pathways in biochemical and cell-based assays.
High purity (≈99.7%), suitable for research applications.
Solid powder form with recommended storage at -20°C; solutions stable at -80°C for long term.
Soluble in DMSO and commonly prepared as 10 mM solutions for in vitro testing.

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1,184

Medchemexpress LLC (E/Z)-Afatinib | 439081-18-2 | MFCD12407405 | 100.0% | 485.94 | C24H25ClFN5O3 | 1 ML

(E/Z)-Afatinib is a research-grade mixture of the E and Z isomers of Afatinib, an irreversible inhibitor of epidermal growth factor receptor (EGFR) family kinases. It is intended for laboratory research use and is supplied as a concentrated solution for biochemical and cell-based assays.

Irreversibly inhibits EGFR, HER2, and HER4.
Mixture of E and Z isomers for comprehensive activity profiling.
Provided as a 10 mM solution in DMSO, 1 mL, suitable for stock preparation.
High purity (99.98% by HPLC) suitable for biochemical assays.
Accompanied by datasheet, certificate of analysis, and safety data sheet.

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1,185

Cayman Chemical 9 Z 11 E 13 EOctadecatrienoic

α-ESA ethyl ester is a neutral, more lipid soluble form of the free acid

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Pyrrolidines

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Medchemexpress LLC 1- Cbz-amino cyclope 10g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Z,E)-9,12-tetradecadien-1-ol | 42521-46-0 | MFCD00270832 | >95.0% | 210.36 g/mol | C14H26O | 1mL Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1- Cbz-amino cyclope 100g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cbz-NH-PEG4-C2-acid | 756526-00-8 | MFCD11041139 | 95.0% | 399.44 g/mol | C19H29NO8 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (Z)-10-hydroxynortriptyline-d3 | 47132-19-4 | 99.0% | 282.40 | C19H18D3NO | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Z-Leu-Leu-Nle-CHO | 133407-83-7 | 97.6% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nikkomycin Z | 59456-70-1 | 98.6% | 495.44 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Z-LLY-FMK | 133410-84-1 | 98.7% | 557.65 g/mol | C30H40FN3O6 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E/Z)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide | 134036-52-5 | MFCD00236452 | 99.7% | 294.30 g/mol | C17H14N2O3 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E/Z)-Afatinib | 439081-18-2 | MFCD12407405 | 100.0% | 485.94 | C24H25ClFN5O3 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More