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Filtered Search Results
Cayman Chemical Bisindolylmaleimide I 10MG
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A highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM); competitive inhibitor for the ATP binding site of PKC; highly selective for PKCα, β1, β2, γ, δ, and ε isozymes; inhibits GSK3 in primary adipocyte lysates (IC50 = 360 nM) and in GSK3β immunoprecipitates derived from rat epididymal adipocytes (IC50 = 170 nM); competitively antagonizes the 5-HT3 receptor with a Ki value of 61 nM
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Ambeed AMBEED
5000892271 R-3-METHYLPYRROLIDINE-3- 100MG
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Medchemexpress LLC Su 5402 | 215543-92-3 | MFCD08235144 | >95.0% | 296.32 | C17H16N2O3 | 50 MG
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SU 5402 is a multi-targeted receptor tyrosine kinase inhibitor active against VEGFR2, FGFR1, and PDGFRβ. It shows low-nanomolar potency for VEGFR2 and FGFR1, is supplied as a powder for research use, and has documented solubility and storage recommendations for experimental workflows.
- Potent inhibition of VEGFR2, FGFR1, and PDGFRβ.
- Low-nanomolar IC50 values for primary targets.
- Suitable for in vitro and in vivo research applications.
- Available in small milligram package sizes for laboratory use.
- High solubility in DMSO and formulated solvent mixes.
- Long-term stability when stored as powder at recommended temperatures.
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Aobchem AOBCHEM
5000962068 3-CHLORO-2- PYRROLIDIN-1-YL -5
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Medchemexpress LLC (Rac)-EBET-1055 | 3031540-65-2 | 97.2% | 923.02 | 100 MG
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(Rac)-EBET-1055 is the racemate of EBET-1055 (HY-161346). It is a bromodomain and extra-terminal (BET) PROTAC degrader that effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC) and simultaneously modulates cancer-associated fibroblast (CAF) activity, upregulating all reporter gene activities in organoid co-cultures. It is for research use only.
- Racemate of EBET-1055
- Bromodomain and extra-terminal (BET) PROTAC degrader
- Effectively inhibits the growth of pancreatic ductal adenocarcinoma (PDAC)
- Modulates cancer-associated fibroblast (CAF) activity
- Upregulates reporter gene activities in organoid co-cultures
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000756888 PEG2-MEN-BOC 500MG
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Medchemexpress LLC TMEM219/IGFBP-3R Hu 50ug | 50ug
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The TMEM219/IGFBP-3R protein was identified as an IGFBP3-specific cell death receptor and a potential mediator of caspase-8-dependent apoptosis upon ligand binding This protein actively binds to IGFBP3 forming a key molecular interaction that may initiate the apoptosis signaling pathway TMEM219/IGFBP-3R Protein Human (HEK293 Fc) is the recombinant human-derived TMEM219/IGFBP-3R protein expressed by HEK293 with C-hFc labeled tag
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Aobchem AOBCHEM
5001051977 8- 3- HYDROXYMETHYL PHENYL -1
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Medchemexpress LLC E/Z-SIB-1893 | 6266-99-5 | 99.8% | 195.26 g/mol | C14H13N | 25 MG
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(E/Z)-SIB-1893 is the racemic mixture of the (E)- and (Z)-isomers of SIB-1893, a selective, non-competitive antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is provided as a 25 mg research sample with reported molecular formula C14H13N, molecular weight 195.26 g/mol, and purity 99.8%.
- Racemic mixture of E and Z isomers for receptor pharmacology studies.
- Selective non-competitive mGluR5 antagonist useful in mGluR5-related assays.
- High reported purity (99.8%) suitable for in vitro experiments.
- Supplied as a 25 mg quantity for small-scale research applications.
- Molecular formula C14H13N and molecular weight 195.26 g/mol provided for reference.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000735216 1-BOC-3-METHYLAMIN 250MG
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eMolecules 548762-66-9 | (2S,5R)-1-Boc-2,5-Dimethylpiperazine | AA Blocks LLC214.309 | C11H22N2O2 | 0.000 | C[C@@H]1CN([C@@H](C)CN1)C(=O)OC(C)(C)C | 25g | 626243024
(2S,5R)-1-Boc-2,5-Dimethylpiperazine | AA Blocks LLC | 548762-66-9214.309 | C11H22N2O2 | 0.000 | C[C@@H]1CN([C@@H](C)CN1)C(=O)OC(C)(C)C | 25g | 626243024
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Medchemexpress LLC Boc-NH-PEG2-CH2CH2COOH | 1365655-91-9 | MFCD22056304 | 98.0% | 277.31 g·mol-1 | C12H23NO6 | 500 MG
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Boc-NH-PEG2-CH2CH2COOH is a Boc-protected, PEG-based linker for assembling PROTAC molecules. It combines a two-unit ethylene glycol spacer with a Boc-protected amino terminus and a terminal propionic acid, enabling versatile conjugation chemistry for connecting target ligands and E3 ligase ligands in small-molecule degraders.
- Boc-protected amino terminus for selective deprotection and coupling.
- Two-unit PEG spacer provides flexibility and appropriate linker length.
- Terminal carboxylic acid enables standard amide or ester bond formation.
- High purity suitable for research-grade synthesis workflows.
- Good solubility in DMSO for easy stock solution preparation.
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Medchemexpress LLC Carbonic anhydrase 9 protein (cynomolgus) | >95.0% | 50UG
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Recombinant cynomolgus carbonic anhydrase 9 (CA9) expressed in HEK293 cells and supplied as a lyophilized, C-terminal His-tagged protein. The product is provided as a sterile powder formulated in PBS with 8% trehalose, characterized by greater than 95% purity and a molecular weight of about 50-60 kDa. It is intended for research on carbonic anhydrase activity, pH regulation, and tumor biology.
- Recombinant protein expressed in HEK293 cells.
- C-terminal His tag enables detection and purification.
- Greater than 95% purity as determined by reducing SDS-PAGE.
- Sequence range Q38-D402 corresponding to the mature protein.
- Lyophilized sterile powder formulated in PBS with 8% trehalose.
- Suggested reconstitution at ≥100 μg/mL in ddH2O.
- Store at -20°C for up to 2 years; aliquot and freeze at -80°C for extended storage.
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![eMolecules 1212307-91-9 | (S)-1-N-CBZ-3-FORMYL-PYRROLIDINE | AstaTech | MFCD06796594 | 233.267 | C13H15NO3 | 97.000 | O=C[C@H]1CCN(C1)C(=O)OCc1ccccc1 | 1g | 112525910](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502170578.JPG-250.jpg)
eMolecules 1212307-91-9 | (S)-1-N-CBZ-3-FORMYL-PYRROLIDINE | AstaTech | MFCD06796594 | 233.267 | C13H15NO3 | 97.000 | O=C[C@H]1CCN(C1)C(=O)OCc1ccccc1 | 1g | 112525910
(S)-1-N-CBZ-3-FORMYL-PYRROLIDINE | AstaTech | 1212307-91-9 | MFCD06796594 | 233.267 | C13H15NO3 | 97.000 | O=C[C@H]1CCN(C1)C(=O)OCc1ccccc1 | 1g | 112525910
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Medchemexpress LLC Sulfo-Cy3 maleimide potassium | 1656990-68-9 | 95.0% | 776.96 g·mol⁻1 | C36H41KN4O9S2 | 5 MG
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Sulfo-Cy3 maleimide potassium is a water-soluble, sulfonated cyanine fluorescent dye bearing a thiol-reactive maleimide group, supplied as the potassium salt for conjugation to cysteine residues. It is formulated for labeling antibodies and other proteins under mild, aqueous conditions and is provided in small, research-scale quantities.
- Water-soluble sulfonated cyanine fluorophore for bright Cy3 emission.
- Thiol-selective maleimide reactive group for cysteine conjugation.
- Potassium salt form improves aqueous solubility.
- Suitable for labeling antibodies and labile proteins in mild conditions.
- Stored sealed and protected from moisture and light to maintain stability.
- Available in small research sizes for reagent-scale experiments.
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