Quinolines and derivatives

Medchemexpress LLC Mexenone | 1641-17-4 | 99.9% | 200 MG

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Mexenone is a potent benzophenone-type UV filter used as a sunscreening agent.

• Potent benzophenone-type UV filter.
• Used for sunscreening.

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Medchemexpress LLC Zm241385 | 139180-30-6 | 99.5% | 337.34 | 200 MG

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Zm241385 | 139180-30-6 | 99.5% | 337.34 | 200 MG

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Ambeed Cycloheptane carboxylic acid

Cycloheptane carboxylic acid, 1460-16-8, 98%

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Medchemexpress LLC ASP-9521 | 1126084-37-4 | 98.0% | 330.42 | 200 MG

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ASP-9521 is a potent, selective, and orally available AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3. It shows more than 100-fold selectivity for AKR1C3 over the isoform AKR1C2. This inhibitor suppresses AD-dependent PSA production and cell proliferation in LNCaP-AKR1C3 cells, and inhibits AD-induced intratumoural T production in CWR22R xenografts for up to 24 hours.

• Potent and selective AKR1C3 inhibitor
• Orally available
• High selectivity over AKR1C2
• Suppresses AD-dependent PSA production and cell proliferation
• Inhibits AD-induced intratumoural T production
• Inhibitory effect maintained for 24 hours

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TARGETMOL CHEMICALS INC MOXIDECTIN 50MG

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Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Moxidectin (CL301423) is an anthelmintic drug which kills parasitic worms and is used for the prevention and control of heartworm and intestinal worms. It can be found in treatments prescribed for animals such as dogs cats horses cattle and sheep. Application methods for moxidectin vary by treatment and include oral topical and injectable solutions. Cydectin Pour On is a trade name for a formulation for use on cattle and red deer. purity: 99%

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eMolecules​ Synthonix Methyl 2-(quinolin-6-yl)acetate 250mg 649427514 M38116 0 000 5622-36-6 MFCD04038669 201 225 C12H11NO2

Synthonix Methyl 2-(quinolin-6-yl)acetate 250mg 649427514 M38116 0 000 5622-36-6 MFCD04038669 201 225 C12H11NO2

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Apexbio Technology LLC Nutlin-3a chiral 675576-98-4 200mg

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Nutlin-3a chiral (CAS 675576-98-4) is a small-molecule antagonist targeting mouse double minute 2 (MDM2) which functions as a negative regulator of the tumor suppressor TP53 By binding directly to the TP53-interacting pocket of MDM2 Nutlin-3a blocks the degradation of TP53 stabilizing the protein and activating TP53-dependent pathways Studies in solid tumors and lymphomas indicate that Nutlin-3a induces cell cycle arrest growth inhibition and apoptosis Research has demonstrated antitumor activity in vitro and in vivo highlighting its utility in studying TP53-related cell signaling pathways and its potential in cancer research applications

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AURUM PHARMATECH INC TERT-BUTYL N-METHYL-N-CARBA 1G

NC3454432 TERT-BUTYL N-METHYL-N-CARBA 1G

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Medchemexpress LLC B7-H2/ICOSLG protein, rat recombinant, C-His tagged | >95.0% | 500 UG

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Recombinant rat B7-H2 (ICOSLG) protein expressed in HEK293 cells and purified for use in binding and functional assays. Supplied lyophilized with a C-terminal His tag, it is intended for research applications studying ICOS-ICOSLG interactions.

• Recombinant rat ICOS ligand expressed in HEK293 cells.
• C-terminal His tag for detection and purification.
• Supplied lyophilized from PBS, pH 7.4.
• Purity >95.0% by reducing SDS-PAGE.
• Sequence corresponds to residues E25-K261.
• Approximate molecular weight 40-60 kDa.
• Recommended reconstitution ≥100 μg/mL; store lyophilized at -20°C.
• Validated in ELISA with ED50 ≈ 89.92 ng/mL.

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