Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC (1E)-CFI-400437 dihydrochloride | 1247000-76-5 | 98.0% | 565.49 | 5 MG
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(1E)-CFI-400437 dihydrochloride is a potent PLK4 inhibitor with high selectivity. It also inhibits Aurora A, Aurora B, KDR, and FLT-3, demonstrating antiproliferative activity. This compound has shown effectiveness in a mouse xenograft model of tumor growth.
- Potent PLK4 inhibitor with IC50 of 0.6 nM
- Selective against other PLK family members
- Inhibits Aurora A, Aurora B, KDR, and FLT-3
- Exhibits antiproliferative activity
- Effective in mouse xenograft models of tumor growth
- Plasma protein binding is 99%
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Apexbio Technology LLC CAY10505 1218777-13-9 200mg
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CAY10505 is a small-molecule inhibitor targeting phosphatidylinositol 3-kinase gamma (PI3K ) It is designed to selectively inhibit PI3K thereby modulating cellular processes governed by the PI3K/Akt/mTOR signaling pathway CAY10505 exerts its biological activity primarily through inhibition of PI3K In cultured neuron studies CAY10505 demonstrates inhibition of baicalein-induced Akt phosphorylation with an IC50 value of approximately 30 nM Based on these pharmacological properties CAY10505 holds research potential in neuroscience cardiovascular biology and cancer biology studies
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669637 CINCHONIDINE STANDA 50MG
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Medchemexpress LLC 5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine | 2095417-73-3 | C31H32N2O9 | 50 MG
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5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is a purine nucleoside analog. This chemical compound is known for its broad antitumor activity, particularly targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and induction of apoptosis, making it a subject of interest in cancer research.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
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eMolecules 4-Hydroxyquinoline-2-carboxylic acid hydrate | 345909-35-5 | MFCD00149476 | 1g
Apollo Scientific | 4-Hydroxyquinoline-2-carboxylic acid hydrate | 1g | 562444254 | OR12784 | | 345909-35-5 | MFCD00149476 | 207.185 | C10H9NO4
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430051 CYANINE5.5 AMINE 25MG
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eMolecules EMOLECULES INC
501713338 N N-DISUCCINIMIDYL CARBON 25G
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eMolecules 8-CHLORONAPHTHALEN-1-AMINE 10G
5000224627 8-CHLORONAPHTHALEN-1-AMINE 10G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430017 VARI FLUOR 532 CARBO 1MG
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Medchemexpress LLC Pomalidomide-amido-C3-COOH | 2162120-77-4 | 99.5% | 387.34 | 100 MG
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Pomalidomide-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide-based cereblon ligand
- Linker used in PROTAC technology
- Intended for research use only
- Solid appearance
- White to light yellow color
- Stable under recommended storage conditions
- Used in cancer and cancer targeted therapy research
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Selleck Chemical LLC SH-4-54
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5 respectively
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Apexbio Technology LLC CP 339818 hydrochloride 50mg
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CP 339818 hydrochloride (CAS 478341-55-8) is a small-molecule antagonist targeting the Kv1 3 potassium channel It is designed to selectively inhibit Kv1 3-mediated ion conductance thereby modulating T-cell activation CP 339818 hydrochloride exerts its biological activity primarily through stabilization of the Kv1 3 channel s C-type inactivation state In in vitro studies CP 339818 hydrochloride demonstrates potent inhibition of Kv1 3 channels with an IC50 value of approximately 200 nM Based on these pharmacological properties CP 339818 hydrochloride holds research potential in the investigation of immune modulation mechanisms relevant to autoimmune and inflammatory disorders
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Cambridge Isotope Laboratories 1 2 3 9-TetraCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 9-TetraCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430838 DIOSMETIN 200MG
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Selleck Chemical LLC SH-4-54
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5 respectively
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