Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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2,791 – 2,805 of 3,759 results

2,791

eMolecules Medchem Express / Ethylhydrocupreine (hydrochloride) / 25mg / 673358916 / HY-136429A / / 3413-58-9 / [null] / 376.930 / C21H29ClN2O2

Medchem Express / Ethylhydrocupreine (hydrochloride) / 25mg / 673358916 / HY-136429A / / 3413-58-9 / [null] / 376.930 / C21H29ClN2O2

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2,792

Medchemexpress LLC 7-PPD | 3081-01-4 | 98.28% | 282.42 | 25 G

7-PPD (DMPPD) is a rubber antioxidant that scavenges free radicals and inhibits the oxidative degradation of rubber chains. It shows promise for research in tire manufacturing and rubber product processing.

Scavenges free radicals.
Inhibits oxidative degradation of rubber chains.
Potential for use in tire manufacturing.
Suitable for rubber product processing research.

Pricing & Availability

2,793

Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 10 G

2-Aminoquinoline (2-Quinolinamine) is a compound that shows promise as a bioavailable neuronal nitric oxide synthase (nNOS) inhibitor. It also exhibits antiviral activity against the vaccinia virus, making it a potential subject for research into antineurodegenerative agents.

Functions as a bioavailable nNOS inhibitor
Demonstrates antiviral activity against vaccinia virus
Useful for research into antineurodegenerative agents
Has a purity of 99.95%

Pricing & Availability

2,794

Medchemexpress LLC 7-Azaindazole | 271-73-8 | 119.12 | 10 G

7-Azaindazole is a biochemical reagent that serves as a versatile building block in chemical synthesis. It can be used as a biological material or organic compound for life science related research.

Used as a ligand for ruthenium (Ru) complexes as a potential anticancer agent.
Used for the synthesis of various derivatives for numerous applications, such as anticancer and antiviral studies.

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2,795

Selleck Chemical LLC Kynurenic acid-100mg

Kynurenic acid (Quinurenic acid, Kynurenate), a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist; It proved to be an antagonist at NMDA, kainate and AMPAreceptors.

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2,796

Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 10 MM * 1 ML

5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. It can inhibit NF-κB activity and induce cancer cell death, showing low cytotoxicity towards normal hematopoietic cells. This compound is used for the research of various cancers, such as leukemia.

Orally active non-competitive 20S proteasome inhibitor
Inhibits NF-κB activity
Induces cancer cell death
Low cytotoxicity towards normal hematopoietic cells
Suitable for cancer research, including leukemia

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2,797

Medchemexpress LLC HSGN-94 | 2570797-85-0 | 98.8% | 508.51 | 1 ML

HSGN-94 is a potent antimicrobial agent that inhibits lipoteichoic acid (LTA) biosynthesis. It is effective against drug-resistant Gram-positive bacteria, including MRSA and Vancomycin-resistant Enterococci, also inhibiting their biofilm formation. It reduces pro-inflammatory cytokines and shows in vivo efficacy in an MRSA murine wound infection model.

Potent antimicrobial agent targeting lipoteichoic acid (LTA) biosynthesis.
Effective against drug-resistant Gram-positive bacteria (MIC values: 0.25-2 μg/mL).
Inhibits biofilm formation in MRSA and Vancomycin-resistant Enterococci.
Reduces pro-inflammatory cytokines.
Demonstrates in vivo efficacy in a murine wound infection model.
Directly binds to CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase (PgsA).
Downregulates PgsA expression in *S. aureus*.
Non-toxic to HaCat cells up to 64 μg/mL.

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2,798

Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | 25 MG

7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis. It functions as an eotaxin/CCL11 inhibitor and a CBR1 inhibitor with an IC50 of 0.28 μM. This compound suppresses eotaxin production and prevents dexamethasone (Dex)-paradoxical adverse effects. Furthermore, 7,4'-DHF inhibits MUC5AC gene expression, mucus production, and secretion by regulating NF-κB, STAT6, and HDAC2, decreasing PMA-stimulated MUC5AC expression in NCI-H292 human airway epithelial cells with an IC50 of 1.4 μM.

Purity: 99.64%
Molecular weight: 254.24
Formula: C15H10O4
CAS number: 2196-14-7
Appearance: Solid, light yellow to yellow
Structure classification: Flavonoids, Flavones, Phenols, Polyphenols
Acts as eotaxin/CCL11 and CBR1 inhibitor (IC50: 0.28 μM)
Inhibits MUC5AC gene expression and mucus production
IC50: 1.4 μM (NCI-H292 human airway epithelial cell)

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2,799

Medchemexpress LLC Cinchonidine (α-Quinidine) | 485-71-2 | 99.6% | 294.39 | 100 G

Cinchonidine (α-Quinidine) is a cinchona alkaloid found in *Cinchona officinalis* and *Gongronema latifolium*. It is a building block used in asymmetric synthesis in organic chemistry. It acts as a weak inhibitor of the serotonin transporter (SERT) and exhibits antimalarial activities.

Derived from *Cinchona officinalis* and *Gongronema latifolium*
Used as a building block in asymmetric synthesis
Weak inhibitor of the serotonin transporter (SERT)
Exhibits antimalarial activities

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2,800

Medchemexpress LLC Oxymatrine | 16837-52-8 | 99.9% | 264.37 | 200 MG

Oxymatrine | 16837-52-8 | 99.9% | 264.37 | 200 MG

Pricing & Availability

2,801

Apexbio Technology LLC Nimorazole 200mg

Nimorazole (6506-37-2) is a nitroimidazole-based small-molecule radiosensitizer designed to enhance cellular radiosensitivity in hypoxic tumor environments Nimorazole exerts its biological activity primarily through metabolic reduction under hypoxic conditions forming reactive intermediates that interact with cellular DNA and augment the effects of radiation therapy In experimental studies nimorazole demonstrates radiosensitizing properties with IC50 values commonly reported in the low millimolar range in vitro although the exact value varies by cell line and context Based on these pharmacological properties nimorazole holds research potential in oncology applications particularly for investigating radiotherapeutic strategies targeting hypoxia-affected neoplastic tissues such as head and neck squamous cell carcinoma

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2,802

Medchemexpress LLC Bx795 | 702675-74-9 | 99.84% | 591.47 | 200 MG

BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. It is also a potent and relatively specific inhibitor of TBK1 and IKKε, having IC50 values of 6 nM and 41 nM, respectively. BX795 works by blocking the phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and exhibits lower selectivity over PKA, PKC, c-Kit, and GSK3β, among others. Additionally, BX795 modulates autophagy.

Effectively blocks PDK1 activity in PC-3 cells.
Inhibits the phosphorylation of S6K1, Akt, PKCδ, and GSK3β.
Potently inhibits tumor cell growth on plastic.
Shows higher growth inhibition in soft agar.
Blocks TBK1- and IKKε-mediated activation of IRF3 and the production of IFN-β.
Demonstrates an inhibitory effect on 2-MeSADP-induced or collagen-induced aggregation, ATP secretion, and thromboxane generation in platelet physiological responses.

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2,803

eMolecules 2-BROMONAPHTHALEN-1-AMINE 25G

5000223897 2-BROMONAPHTHALEN-1-AMINE 25G

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2,804

Apexbio Technology LLC Oxymatrine 16837-52-8 200mg

Oxymatrine (CAS 16837-52-8) is a quinolizidine alkaloid extracted from Sophora flavescens It has been shown to modulate multiple cellular pathways associated with fibrosis and neurodegeneration including inhibition of TGF- 1-mediated signaling and reduction of pro-inflammatory cytokine expression Oxymatrine exhibits antifibrotic and neuroprotective properties in various experimental models It is also extensively studied for its antiviral activity against hepatitis B virus and has been applied in traditional Chinese medicine for hepatitis management This compound is valuable for investigating mechanisms of fibrosis neuroprotection and viral pathogenesis

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2,805

Apexbio Technology LLC STF 31 724741-75-7 50mg

STF 31 (CAS 724741-75-7) is a small-molecule inhibitor targeting glucose transporter 1 (GLUT1) with an IC50 of 1 M By antagonizing GLUT1 STF 31 disrupts glucose uptake selectively impairing survival in VHL-deficient renal cell carcinoma (RCC) models that depend on enhanced glycolysis In vitro STF 31 exhibits selective cytotoxicity toward VHL-deficient RCC4 cells while exerting minimal effects on RCC4/VHL controls In vivo administration of STF 31 analogs retards tumor growth in VHL-deficient RCC xenografts without notable toxicity in mice STF 31 is utilized in research to investigate GLUT1-mediated metabolic dependencies and therapeutic vulnerabilities in cancer and neuroinflammatory models

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Quinolines and derivatives

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Medchemexpress LLC 7-PPD | 3081-01-4 | 98.28% | 282.42 | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 7-Azaindazole | 271-73-8 | 119.12 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HSGN-94 | 2570797-85-0 | 98.8% | 508.51 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cinchonidine (α-Quinidine) | 485-71-2 | 99.6% | 294.39 | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Oxymatrine | 16837-52-8 | 99.9% | 264.37 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Nimorazole 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bx795 | 702675-74-9 | 99.84% | 591.47 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Oxymatrine 16837-52-8 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC STF 31 724741-75-7 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More