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Filtered Search Results
TARGETMOL CHEMICALS INC Parthenolide 200MG
Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-kB inhibitor and also specifically inhibits HDAC1 protein, but is inactive against other class I/II HDACs. Parthenolide has anti-inflammatory, anti-tumor, and anti-viral activities. Purity 99.33%
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TARGETMOL CHEMICALS INC Triclabendazole 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease. Purity 98.35%
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Apexbio Technology LLC Phenanthrene 85-01-8 200mg
Phenanthrene is a polycyclic aromatic hydrocarbon (PAH) that exerts its biological activity primarily through the induction of cellular inflammatory responses enhancement of reactive oxygen species (ROS) generation and activation of apoptotic signaling pathways Based on these pharmacological properties phenanthrene is utilized in research to study PAH-induced cellular toxicity oxidative stress mechanisms and programmed cell death pathways Additionally it serves as a representative analyte in environmental toxicology investigations to detect quantify and evaluate PAH contamination in water and soil supporting the development of toxicological evaluation models and detection methods
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TARGETMOL CHEMICALS INC Oxaliplatin 200MG
Also available in 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autophagy. Purity 99.93%
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TARGETMOL CHEMICALS INC Fluvastatin sodium 200MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent. Purity 99.46%
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TARGETMOL CHEMICALS INC Matrine 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. Purity 97.16%
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Medchemexpress LLC Tetrabenazine | 200MG
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Tetrabenazine | 200MG
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Medchemexpress LLC Mezlocillin (sodium) | 42057-22-7 | 98.1% | 200 MG
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Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research.
- Semisynthetic and extended-spectrum antibiotic
- Active against both gram-negative and gram-positive bacteria
- Can be used in bacterial infection research
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TARGETMOL CHEMICALS INC AG490 200MG
Also available in 1 mL, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50 0.1 uM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src. Purity 99.7%
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TARGETMOL CHEMICALS INC Tebufenozide 200MG
Also available in 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests. Purity 98.04%
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Medchemexpress LLC Elesclomol | 488832-69-5 | >98.0% | 200MG
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Elesclomol | 488832-69-5 | >98.0% | 200MG
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Apexbio Technology LLC MLN8054 869363-13-3 200mg
MLN8054 (CAS 869363-13-3) is a small-molecule inhibitor targeting Aurora A kinase (AAK) It exhibits ATP-competitive reversible inhibition and demonstrates high selectivity for AAK with an IC50 of 4 nM showing 40-fold and 100-fold greater selectivity over Aurora B kinase and other kinases respectively In cellular studies MLN8054 impairs AAK function leading to inactivation of the protein Pt288 disruption of mitotic spindle formation G2/M phase cell cycle arrest and induction of apoptosis In preclinical tumor xenograft models MLN8054 has demonstrated antitumor activity This compound is widely utilized in research focused on cell cycle regulation mitosis and the therapeutic targeting of cancer
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Accela Chembio Inc 5-nitroquinoline | 25g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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5-nitroquinoline | 25g | 607-34-1 | MFCD00006790 | 98% | Shelf Life: 1980 Days | Light Sensitive
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Medchemexpress LLC Hydroquinidine (Dihydroquinidine) | 1435-55-8 | 99.9% | 50 G
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Hydroquinidine (Dihydroquinidine) is a potent ion channel blocker that demonstrates strong anti-cancer activity against colon, pancreatic, and hepatocellular cancer cells. It also prolongs the QT interval and possesses antiarrhythmic efficacy.
- Exhibits anti-clonogenic and anti-tumorigenic activities in pancreatic cancer cells in vitro.
- Gene expression profiling shows changes in CDKN1A, CDKN1B, PUMA, BIRC5, AKT, MKI67, PCNA, and CCNE1 in various cancer cell lines.
- Investigated for Brugada Syndrome in a Phase 3 clinical trial.
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Apexbio Technology LLC Cinchonine(LA40221) 118-10-5 25mg
Cinchonine LA40221 (118-10-5) is a small-molecule inhibitor designed to modulate biological processes such as inflammation tumorigenesis malaria infection obesity and platelet aggregation Cinchonine LA40221 exerts its biological activity primarily through regulation of signaling pathways modulation of enzyme activities and induction of apoptosis via caspase-3-dependent mechanisms In in vitro studies Cinchonine LA40221 demonstrates antitumor activity with IC50 values ranging approximately from 10-100 M depending on cell types and protocols Based on these pharmacological properties Cinchonine LA40221 holds research potential in studying malaria infection models cancer cell apoptosis inflammatory responses platelet function and obesity-related metabolic pathways
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