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Filtered Search Results
TARGETMOL CHEMICALS INC JH-RE-06 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POL(zeta). JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 uM; Kd=0.42 uM) which targets REV1 that interacts with the REV7 subunit of POL(zeta). JH-RE-06 also improves chemotherapy. purity: 99%
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Apexbio Technology LLC LY2784544 1229236-86-5 200mg
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LY2784544 (CAS 1229236-86-5) is a potent and selective ATP-competitive inhibitor of JAK2 tyrosine kinase exhibiting an IC50 of 3 nM It demonstrates 8-fold and 16-fold selectivity over JAK1 and JAK3 respectively In cellular assays LY2784544 effectively inhibits STAT5 phosphorylation in Ba/F3-TEL-JAK2 cells (IC50 0 191 nM) while displaying substantially reduced activity against JAK1 and JAK3-dependent STAT5 phosphorylation The compound suppresses proliferation and induces apoptosis in cells harboring the JAK2 V617F mutation In murine models it reduces tumor burden and strongly inhibits STAT5 phosphorylation in JAK2 V617F-driven cells LY2784544 is a valuable tool for studying JAK2-mediated signaling and myeloproliferative neoplasms
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Apexbio Technology LLC Amadacycline 389139-89-3 200mg
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Amadacycline (CAS 389139-89-3) is a tetracycline-class antibiotic targeting the bacterial ribosomal 30S subunit It is designed to inhibit bacterial protein synthesis thereby preventing microbial proliferation Amadacycline exerts its biological activity primarily through interference with bacterial translation by inhibiting the 30S ribosomal subunit The exact IC50 value for Amadacycline has not been established Based on these pharmacological properties Amadacycline holds research potential in investigating antibiotic resistance mechanisms bacterial ribosome-targeting strategies and as a candidate in studies evaluating therapeutic agents for complicated skin and skin structure infections
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TARGETMOL CHEMICALS INC ALACEPRIL 50MG
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Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor used as an antihypertensivepurity: 98%
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Ambeed Methyl 5bromo6oxo1 6dihydropyr
Methyl 5-bromo-6-oxo-1,6-dihydropyridine-2-carboxylate, 178876-86-3, 98%
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eMolecules 5-HYDROXYQUINOLINE-4-CARBOXYLIC ACID | 1261462-15-0 | MFCD18417134 | 1g
AstaTech | 5-HYDROXYQUINOLINE-4-CARBOXYLIC ACID | 1g | 384830046 | 86125 | 95.000 | 1261462-15-0 | MFCD18417134 | 189.170 | C10H7NO3
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Medchemexpress LLC Methyl phenyl sulfone | 3112-85-4 | MFCD00014741 | 50g
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Methyl phenyl sulfone is a drug impurity
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Medchemexpress LLC Cytochrome c (bovine heart) | 9007-43-6 | MFCD00130890 | 95.0% | 12,327 Da | 200MG
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Cytochrome c (bovine heart) is a heme-containing mitochondrial protein provided as a lyophilized powder for research use. It functions in electron transport and is commonly used as a reagent or standard in biochemical assays of oxidative phosphorylation, electron-transfer reactions, and apoptosis research. The material is characterized by its protein sequence and heme prosthetic group and is supplied at ~95% purity.
- Heme-containing mitochondrial protein suitable for biochemical studies.
- Commonly used as a reagent or standard in electron transport and apoptosis assays.
- Provided as a lyophilized powder for convenient storage and handling.
- Purity approximately 95.0% as listed by the manufacturer.
- Available in multiple pack sizes, including a 200 mg pack.
- Identified by CAS number 9007-43-6 for reference and traceability.
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TARGETMOL CHEMICALS INC BEPRIDIL HYDROCHLORIDE 50MG
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Also available in 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels. purity: 99%
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Apexbio Technology LLC PP121 1092788-83-4 200mg
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PP121 (CAS 1092788-83-4) is a dual inhibitor of tyrosine kinases and phosphoinositide kinases It demonstrates potent inhibition of PI3K isoforms p110 (IC50 52 nM) p110 (1 4 M) p110 (1 1 M) p110 (150 nM) as well as DNA-PK (60 nM) and mTOR (10 nM) it does not affect serine/threonine kinases PP121 also targets multiple tyrosine kinases including Ab1 (21 nM) Hck (4 nM) Src (10 nM) VEGFR2 (55 nM) EGFR (550 nM) EphB4 (220 nM) and PDGFR ( 1 nM) In cell-based studies PP121 reverses v-Src mediated cell transformation restores actin stress fiber staining and inhibits mutant Ret kinase in thyroid tumor models with sub-nanomolar potency It is used to investigate kinase cross-talk and mechanisms underlying drug resistance
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Medchemexpress LLC Sulfo-EGS 10mg | 167410-92-6 | 10 MG
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Sulfo-EGS is a water-soluble, homobifunctional, amine-reactive crosslinker used to covalently link proximal primary amines in proteins and peptides to map interactions and probe complex topology. It is provided for research use in small milligram quantities.
- Water-soluble homobifunctional amine-reactive crosslinker.
- Targets primary amines for covalent crosslinking of proteins and peptides.
- Facilitates mapping of protein-protein and protein-peptide interactions.
- Suitable for small-scale, solution-phase crosslinking experiments.
- Available in milligram pack sizes for research applications.
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Medchemexpress LLC 3-sulfo-taurocholic acid disodium salt | 71781-33-4 | 99.0% | 639.73 | C26H43NNa2O10S2 | 1mg
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3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine TCA3S) is a metabolite of the conjugated bile acid taurocholic acid Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL
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TARGETMOL CHEMICALS INC Altrenogest 200MG
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Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Altrenogest (Allyltrenbolone)(A35957; RU2267), a progestogen, has structural relation with veterinary steroid trenbolone. Purity 99.61%
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Apexbio Technology LLC Amorolfine HCl 78613-38-4 200mg
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Amorolfine hydrochloride (78613-38-4) is a small-molecule inhibitor targeting 14-reductase and 7 8-isomerase enzymes essential for fungal ergosterol synthesis It is designed to disrupt fungal sterol biosynthesis thereby impairing membrane stability and fungal cell viability Amorolfine hydrochloride exerts its biological activity primarily through inhibition of 14-reductase and 7 8-isomerase In in vitro studies Amorolfine hydrochloride demonstrates antifungal activity with IC50 values ranging from approximately 0 02 to 0 5 g/mL depending on fungal species and experimental conditions Based on these pharmacological properties Amorolfine hydrochloride holds research potential in investigating antifungal activity against fungal pathogens including models of human nail infection
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TARGETMOL CHEMICALS INC Oxypurinol 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure. Purity 100%
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