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Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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eMolecules​ 1-Bromo-4-chloro-2-(difluoromethoxy)benzene | 1056942-37-0 | MFCD14698391 | 250mg

Ambeed | 1-Bromo-4-chloro-2-(difluoromethoxy)benzene | 250mg | 600836041 | A274545 | | 1056942-37-0 | MFCD14698391 | 257.460 | C7H4BrClF2O

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Apexbio Technology LLC PF-2545920 1292799-56-4 200mg
SDP

PF-2545920 is a small-molecule inhibitor targeting phosphodiesterase 10A (PDE10A) It is designed to selectively inhibit PDE10A thereby modulating neuronal cAMP and cGMP signaling within cortico-striato-thalamic circuits PF-2545920 exerts its biological activity primarily through selective inhibition of PDE10A In in vitro studies PF-2545920 demonstrates potent inhibitory activity with an IC50 value of 0 37 nM In experimental mouse models it increases striatal cGMP levels at doses around 1 mg/kg Based on these pharmacological properties PF-2545920 holds research potential in the investigation of PDE10A-associated neurobiology and neuropsychiatric conditions such as schizophrenia

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