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Apexbio Technology LLC NS 1619 153587-01-0 10mg
NS 1619 (CAS 153587-01-0) is a small molecule opener of large-conductance calcium-activated potassium (BK) channels By enhancing BK channel activity NS 1619 modulates membrane potential and smooth muscle tone In vascular smooth muscle assays it demonstrates an EC50 of 10 30 M Experimental studies indicate that NS 1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells This compound is commonly utilized in research focused on vascular disorders and oncology to investigate BK channel-related signaling pathways and their physiological or pathological implications
