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Olanzapine (CAS 132539-06-1) is a small molecule antagonist with high affinity for serotonin 5-HT2 and dopamine D2 receptors both classified as G protein-coupled receptors (GPCRs) In vitro binding studies demonstrate Olanzapine interacts at nanomolar concentrations with dopaminergic serotonergic 1-adrenergic and muscarinic receptors In vivo Olanzapine antagonizes dopamine and serotonin receptors and exhibits weaker efficacy at -adrenergic and muscarinic sites Administration in animal models increases extracellular dopamine and norepinephrine levels in specific brain regions in a dose-dependent manner Olanzapine is widely utilized in neuropharmacological research to investigate antipsychotic mechanisms
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Olanzapine (CAS 132539-06-1) is a small molecule antagonist with high affinity for serotonin 5-HT2 and dopamine D2 receptors both classified as G protein-coupled receptors (GPCRs) In vitro binding studies demonstrate Olanzapine interacts at nanomolar concentrations with dopaminergic serotonergic 1-adrenergic and muscarinic receptors In vivo Olanzapine antagonizes dopamine and serotonin receptors and exhibits weaker efficacy at -adrenergic and muscarinic sites Administration in animal models increases extracellular dopamine and norepinephrine levels in specific brain regions in a dose-dependent manner Olanzapine is widely utilized in neuropharmacological research to investigate antipsychotic mechanisms
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Olanzapine (CAS 132539-06-1) is a small molecule antagonist with high affinity for serotonin 5-HT2 and dopamine D2 receptors both classified as G protein-coupled receptors (GPCRs) In vitro binding studies demonstrate Olanzapine interacts at nanomolar concentrations with dopaminergic serotonergic 1-adrenergic and muscarinic receptors In vivo Olanzapine antagonizes dopamine and serotonin receptors and exhibits weaker efficacy at -adrenergic and muscarinic sites Administration in animal models increases extracellular dopamine and norepinephrine levels in specific brain regions in a dose-dependent manner Olanzapine is widely utilized in neuropharmacological research to investigate antipsychotic mechanisms
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More