Human GIP(3-30), amide is a high-affinity antagonist of the human GIP receptor in vitro, with potential anti-obesity and anti-diabetic effects. It competitively binds to the GIP receptor, inhibiting GIP-mediated cAMP accumulation, β-arrestin recruitment, and receptor internalization. It also inhibits GIP-mediated insulin secretion and signal transduction in adipocytes.
- High-affinity antagonist of human GIP receptor.
- Potential anti-obesity and anti-diabetic effects.
- Inhibits GIP-mediated cAMP accumulation and insulin secretion.
- Purity of 99.8%.
- Powder storage: -80°C for 2 years or -20°C for 1 year.
- For research use only.