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Lornoxicam (Chlortenoxicam) is a non-steroidal COX-1/COX-2 inhibitor used as an anti-inflammatory drug to treat pain osteoarthritis and rheumatoid arthritis
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Lornoxicam (CAS 70374-39-9) is an oxicam-class nonsteroidal anti-inflammatory drug (NSAID) that exerts its pharmacological effects primarily by potent inhibition of cyclooxygenase isoforms COX-1 and COX-2 with in vitro IC50 values of 5 nM and 8 nM respectively Studies in intact human cells and whole blood confirm its strong suppressive activity against both COX isoenzymes Additionally lornoxicam displays dose-dependent inhibition of nitric oxide formation (IC50 65 M) and reduction of IL-6 production in vitro Due to its robust COX inhibition and favorable pharmacokinetic profile lornoxicam is widely utilized as a research tool in studies investigating inflammation pain pathways and COX-mediated prostaglandin synthesis
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Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor. purity: 100%
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