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2-Thiouracil is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. It antagonizes BH4-induced nNOS dimerization and is also known as an antithyroid compound and a highly specific melanoma detector. It has been shown to stimulate the growth of pea and corn root segments.
Significantly reduces the number of nNOS dimers
Inhibits conventional oligomerization of indole
Generates new major products including DHI-TU adducts
Stimulates root growth in pea and corn roots
Rapidly incorporates into tumor pigment in melanoma-bearing mice
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2-Thiouridine is a modified nucleoside provided as a ready-to-use 10 mM solution in DMSO for biochemical and virology research, used to study RNA base-pairing, nonenzymatic replication, and antiviral activity.
Ready-to-use 10 mM solution in DMSO.
Supplied volume 1 mL.
Reported purity 99.7%.
Molecular weight 260.27 g/mol.
CAS number 20235-78-3.
In-solution storage: -80°C (6 months) or -20°C (1 month).
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2-Thiouridine is a thiolated uridine nucleoside used in biochemical and nucleic acid research. The compound contains a sulfur substituent at the 2-position of the nucleobase and is provided as a high-purity solid or as pre-formulated DMSO solutions for assay-ready use.
High purity suitable for research use.
Molecular weight 260.27 g/mol; formula C9H12N2O5S.
Available in solid quantities from 50 mg up to 50 g.
Offered as 10 mM DMSO solutions for convenience.
Commonly used in RNA modification studies and enzymology.
Supplied with a certificate of analysis documenting batch purity.
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