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Filtered Search Results
eMolecules 52532-63-5 | Ambeed | 5-Aminothiophene-2-carbonitrile | 100mg | 552557443 | A127214 | MFCD19204377 | 124.16 | C5H4N2S
Ambeed | 5-Aminothiophene-2-carbonitrile | 100mg | 552557443 | A127214 | 52532-63-5 | MFCD19204377 | 124.160 | C5H4N2S
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Advanced Chemblocks Inc 1-NONYLPIPERIDINE-4-CARBOXYL1G
1-Nonylpiperidine-4-carboxylic acid, 1g, 1156807-77-0
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Medchemexpress LLC Prlx-93936 (dihydrochloride) | 1094210-96-4 | 99.8% | 1 MG
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PRLX-93936 dihydrochloride is a small-molecule HIF-1α inhibitor with reported anticancer activity that can suppress the activated Ras signaling pathway and is supplied as a solid research reagent for preclinical studies.
- Inhibits HIF-1α and suppresses Ras pathway signaling.
- High reported purity (99.8%).
- Solid form, suitable for storage and formulation.
- Molecular weight 437.36 g/mol; formula C21H26Cl2N4O2.
- Recommended storage: 4°C sealed; in solution -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human use.
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Medchemexpress LLC Ro 10-5824 dihydrochloride | 189744-94-3 | 99.9% | 353.29 g/mol | C17H22Cl2N4 | 10 MG
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Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist used in neuroscience and receptor pharmacology research. It binds the D4 receptor with high affinity (Ki ≈ 5.2 nM), shows pronounced selectivity over other dopamine receptor subtypes, and produces partial agonist responses in functional assays; in vivo studies report effects on object recognition and frontal cortex gamma activity without altering spontaneous locomotion.
- High-affinity D4 receptor binding (Ki ≈ 5.2 nM).
- Pronounced selectivity versus other dopamine receptor subtypes.
- Partial agonist activity in functional assays (35S-GTPγS stimulation).
- Demonstrated in vivo activity relevant to cognition and neural oscillations.
- High chemical purity suitable for in vitro and in vivo research.
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Apexbio Technology LLC Quinacrine 2HCl 69-05-6 50mg
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Quinacrine 2HCl (69-05-6) is an orally active small-molecule inhibitor targeting the NF- B signaling pathway It is designed to inhibit the NF- B cascade thereby downregulating pro-survival gene expression and promoting apoptotic pathways in tumor cells Quinacrine 2HCl exerts its biological activity primarily through inhibition of NF- B and activation of the p53-dependent apoptotic pathway In in vitro studies Quinacrine 2HCl demonstrates growth inhibition of multiple cancer cell lines with reported IC50 values generally in the low micromolar range depending on the specific cell model and experimental context Based on these pharmacological properties Quinacrine 2HCl holds research potential in investigating apoptosis regulatory mechanisms NF- B pathway involvement in cancer biology and preclinical evaluation of potential anticancer therapies
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Apexbio Technology LLC Clozapine N-oxide(CNO) dihydrochloride(Synonyms: CNO dihydrochloride, Clozapine N-oxide hydrochloride,Clozapine N-oxide dihydrochloride), 25mg, CAS: 2250025-93-3.
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Clozapine N-oxide (CNO) dihydrochloride (CAS 2250025-93-3) is a synthetic metabolite derived from clozapine commonly utilized as an agonist for designer receptors exclusively activated by designer drugs (DREADDs) In neuroscience research CNO selectively binds and activates engineered muscarinic receptors particularly hM3Dq and hM4Di thereby influencing neuronal signaling upon penetrating the blood-brain barrier Due to its specificity CNO dihydrochloride serves as a valuable tool for dissecting neuronal circuits and elucidating their functional roles in behavioral studies
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Apexbio Technology LLC Ranolazine 2HCl 95635-56-6 100mg
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Ranolazine 2HCl (CAS 95635-56-6) is a small molecule frequently utilized in cardiovascular research for its antianginal and antiarrhythmic activities It modulates cardiac metabolism by partially inhibiting fatty acid -oxidation thereby increasing reliance on glucose oxidation This metabolic shift is mediated through activation of pyruvate dehydrogenase in ischemic myocytes enhancing glucose utilization during myocardial ischemia Ranolazine 2HCl s ability to alter substrate preference and improve cellular energetics under hypoxic conditions supports its application in studies of cardiac ischemia arrhythmias and myocardial metabolism
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Medchemexpress LLC Lesopitron dihydrochloride | 132449-89-9 | MFCD00894211 | 98.0% | 393.74 g/mol | C15H23Cl3N6 | 1 MG
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Lesopitron dihydrochloride is a selective, full agonist of the serotonin 5-HT1A receptor used for preclinical in vitro pharmacology and receptor-binding studies. It shows an IC50 of 125 nM in rat hippocampal membranes and is supplied as the dihydrochloride salt at high purity for research use.
- High purity (98.0%).
- Molecular formula C15H23Cl3N6; molecular weight 393.74 g/mol.
- Selective 5-HT1A receptor agonist (IC50 = 125 nM in rat hippocampal membranes).
- Suitable for in vitro receptor pharmacology and binding assays.
- Available in small research pack sizes (e.g., 1 mg).
- Analytical documentation available (COA, HNMR, SDS).
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Aobchem 3 5-Dibromo-2-fluorochlorobenzene | ≥97% | CAS 1000573-27-2 | C6H2Br2ClF | 250mg
3 5-Dibromo-2-fluorochlorobenzene | ≥97% | CAS 1000573-27-2 | C6H2Br2ClF | 250mg
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Aobchem Methyl 5-butylthiophene-2-carboxylate | ≥97% | CAS 161618-23-1 | C10H14O2S | 500mg
Methyl 5-butylthiophene-2-carboxylate | ≥97% | CAS 161618-23-1 | C10H14O2S | 500mg
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Aobchem 3 5-Dibromo-1-benzyloxybenzene | ≥97% | CAS 128924-01-6 | C13H10Br2O | 5g
3 5-Dibromo-1-benzyloxybenzene | ≥97% | CAS 128924-01-6 | C13H10Br2O | 5g
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Aobchem AOBCHEM
5000969137 METHYL 4-DECYLTHIOPHENE-2-CARB
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Aobchem AOBCHEM
5000969668 3 5-DIBROMO-2-FORMYLPHENYLBORO
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Aobchem AOBCHEM
5001002932 1 3-DIBROMO-2-VINYLBENZENE 500
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Aobchem AOBCHEM
5001003394 2 3-DIBROMO-6-ETHOXYPYRIDINE 1
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