Thiophenes
Sigma Aldrich Diethyl oxalacetate sodium salt
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 4-Methyl-1-piperazinecarbonyl chloride hydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
![Sigma Aldrich 6-Bromo-2H-benzo[b][1,4]thiazin-3(4H)-one](https://assets.fishersci.com/TFS-Assets/CCG/Sigma-Aldrich/product-images/f31774a6-4049-442c-880e-ea3fd5b47069.jpg-250.jpg)
Sigma Aldrich 6-Bromo-2H-benzo[b][1,4]thiazin-3(4H)-one
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2,6-Dichlorobenzaldehyde
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2,4-Dimethylaniline
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich N,N-Dimethyl-4-azepanamine dihydrochloride
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Sigma Aldrich 2,5-Diiodothiophene
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Medchemexpress LLC Puromycin dihydrochloride | 58-58-2 | MFCD00012691 | 99.9% | 500 MG
Puromycin dihydrochloride is an aminonucleoside antibiotic that inhibits protein synthesis. It blocks protein synthesis after aminoacyl-sRNA formation, leading to the accumulation of small peptides. It induces premature termination of translation by serving as an acceptor substrate and by competing with aminoacyl-tRNA for binding to the A' site. This allows for direct evaluation of translation activity in single cells using immunofluorescence microscopy and in heterogeneous cell populations via fluorescence-activated cell sorting.
- Aminonucleoside antibiotic
- Inhibits protein synthesis
- Blocks protein synthesis after aminoacyl-sRNA formation
- Leads to the accumulation of small peptides
- Causes premature termination of translation
- Allows direct evaluation of translation activity in single cells by immunofluorescence microscopy and in heterogeneous cell populations by fluorescence-activated cell sorting
eMolecules 6165-68-0 | Thiophen-2-ylboronic acid | Ambeed | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 552669677
Thiophen-2-ylboronic acid | Ambeed | 6165-68-0 | MFCD00151850 | 127.950 | C4H5BO2S | 98.000 | OB(O)c1cccs1 | 25g | 552669677
Medchemexpress LLC Nolatrexed dihydrochloride | 152946-68-4 | 98.5% | 357.26 | 50 MG
Nolatrexed dihydrochloride (AG 337) is an orally active and non-competitive lipophilic inhibitor of thymidylate synthase with a Ki of 11 nM for human thymidylate synthase. It interacts at the folate cofactor binding site of the enzyme. Nolatrexed dihydrochloride increases sulfotransferases and induces cell cycle arrest in the S phase of cancer cells. It also exhibits anticancer activity against cervical cancer.
- Orally active and non-competitive lipophilic inhibitor of thymidylate synthase.
- Interacts at the folate cofactor binding site of the enzyme.
- Increases sulfotransferases.
- Induces cell cycle arrest in the S phase of cancer cells.
- Exhibits anticancer activity against cervical cancer.
Medchemexpress LLC Lanicemine dihydrochloride | 153322-06-6 | 99.9% | 271.19 g/mol | C13H16Cl2N2 | 1 ML
Lanicemine dihydrochloride is a low-trapping NMDA receptor channel blocker (AZD6765) provided as a 10 mM solution in DMSO for laboratory research. It is used in pharmacology and neuroscience studies to examine NMDA receptor modulation and antidepressant-like effects. The compound has CAS 153322-06-6 and a molecular weight of 271.19 g/mol.
- Supplied as 10 mM solution in DMSO, 1 mL
- High stated purity (99.94%) suitable for research applications
- Low-trapping NMDA receptor antagonist for pharmacological studies
- Relevant for studies of antidepressant mechanisms and synaptic transmission
- Molecular formula C13H16Cl2N2; molecular weight 271.19 g/mol
eMolecules 52532-63-5 | Ambeed | 5-Aminothiophene-2-carbonitrile | 100mg | 552557443 | A127214 | MFCD19204377 | 124.16 | C5H4N2S
Ambeed | 5-Aminothiophene-2-carbonitrile | 100mg | 552557443 | A127214 | 52532-63-5 | MFCD19204377 | 124.160 | C5H4N2S
Apexbio Technology LLC Quinacrine 2HCl 69-05-6 50mg
Quinacrine 2HCl (69-05-6) is an orally active small-molecule inhibitor targeting the NF- B signaling pathway It is designed to inhibit the NF- B cascade thereby downregulating pro-survival gene expression and promoting apoptotic pathways in tumor cells Quinacrine 2HCl exerts its biological activity primarily through inhibition of NF- B and activation of the p53-dependent apoptotic pathway In in vitro studies Quinacrine 2HCl demonstrates growth inhibition of multiple cancer cell lines with reported IC50 values generally in the low micromolar range depending on the specific cell model and experimental context Based on these pharmacological properties Quinacrine 2HCl holds research potential in investigating apoptosis regulatory mechanisms NF- B pathway involvement in cancer biology and preclinical evaluation of potential anticancer therapies
Apexbio Technology LLC Clozapine N-oxide(CNO) dihydrochloride(Synonyms: CNO dihydrochloride, Clozapine N-oxide hydrochloride,Clozapine N-oxide dihydrochloride), 25mg, CAS: 2250025-93-3.
Clozapine N-oxide (CNO) dihydrochloride (CAS 2250025-93-3) is a synthetic metabolite derived from clozapine commonly utilized as an agonist for designer receptors exclusively activated by designer drugs (DREADDs) In neuroscience research CNO selectively binds and activates engineered muscarinic receptors particularly hM3Dq and hM4Di thereby influencing neuronal signaling upon penetrating the blood-brain barrier Due to its specificity CNO dihydrochloride serves as a valuable tool for dissecting neuronal circuits and elucidating their functional roles in behavioral studies
Selleck Chemical LLC TLR7/8 agonist 1 2HCl
TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC50 of 20 nM