Thiophenes
Apexbio Technology LLC Quinacrine 2HCl 69-05-6 10mM (in 1mL H2O)
Quinacrine 2HCl (69-05-6) is an orally active small-molecule inhibitor targeting the NF- B signaling pathway It is designed to inhibit the NF- B cascade thereby downregulating pro-survival gene expression and promoting apoptotic pathways in tumor cells Quinacrine 2HCl exerts its biological activity primarily through inhibition of NF- B and activation of the p53-dependent apoptotic pathway In in vitro studies Quinacrine 2HCl demonstrates growth inhibition of multiple cancer cell lines with reported IC50 values generally in the low micromolar range depending on the specific cell model and experimental context Based on these pharmacological properties Quinacrine 2HCl holds research potential in investigating apoptosis regulatory mechanisms NF- B pathway involvement in cancer biology and preclinical evaluation of potential anticancer therapies
Apexbio Technology LLC Cyclizine 2HCl 5897-18-7 50mg
Cyclizine 2HCl (CAS 5897-18-7) is a synthetic piperazine derivative that functions as an antagonist at histamine H1 receptors By inhibiting H1 receptor-mediated signaling Cyclizine 2HCl effectively suppresses histamine-induced physiological responses including those involved in allergic reactions and motion sickness This compound is widely utilized in biomedical research to investigate histaminergic pathways allergic mechanisms and the pharmacological modulation of H1 receptor activity Its antagonist properties make it valuable for studies examining the mechanistic basis of histamine-mediated processes and for evaluating novel anti-allergic therapeutics
Medchemexpress LLC Ro 10-5824 dihydrochloride | 189744-94-3 | 99.9% | 353.29 | C17H22Cl2N4 | 1 ML
Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO (1 mL) or as a solid, and is characterized for potency, purity, and identity for receptor pharmacology and in vitro studies.
- Selective dopamine D4 receptor partial agonist with reported Ki = 5.2 nM.
- Provided as a 10 mM solution in DMSO (1 mL) or as solid quantities for custom dosing.
- High purity (reported 99.86%), suitable for analytical and biological assays.
- Molecular weight 353.29, chemical formula C17H22Cl2N4, CAS 189744-94-3.
- Characterized with supporting documentation including datasheet, COA, LCMS, and SDS.
- Intended for receptor pharmacology, signaling studies, and in vitro assay applications.
Medchemexpress LLC Methyl 3-aminopyridine-4-carboxylate | 55279-30-6 | 152.15 | 10 G
Methyl 3-aminopyridine-4-carboxylate is a biochemical reagent suitable for life science-related research. This compound is provided as an off-white to yellow solid.
- Biochemical reagent for research
- Suitable for biological material or organic compound studies
- Appears as an off-white to yellow solid
- Requires protection from light during storage
Medchemexpress LLC 2-Chloro-5-thiophenecarboxaldehyde | 7283-96-7 | 146.59 | 10 G
2-Chloro-5-thiophenecarboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Used as a biological material or organic compound for life science related research
Medchemexpress LLC Lesopitron dihydrochloride | 132449-89-9 | 98.0% | 393.74 g/mol | C15H23Cl3N6 | 5 MG
Lesopitron dihydrochloride is a selective, full agonist of the 5-HT1A receptor used in research to investigate serotonergic signaling and pharmacology. Supplier-reported data indicate activity in rodent tissues (IC50 ≈125 nM) and effects on adenylate cyclase activity and neuronal firing, supporting use in both in vitro and in vivo studies.
- Selective full 5-HT1A receptor agonist.
- Reported IC50 ≈125 nM in rat hippocampal membranes.
- Modulates forskolin-stimulated adenylate cyclase activity.
- Demonstrated activity in vitro and in vivo assays.
- Supplied in small, research-oriented pack sizes for pharmacology studies.
Medchemexpress LLC Way-100135 dihydrochloride | 149055-79-8 | 98.1% | 468.46 g/mol | C24H35Cl2N3O2 | 5 MG
WAY-100135 dihydrochloride is a research-grade small molecule used as a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. Supplied as the dihydrochloride salt with reported in vitro potency (IC50 ≈ 34 nM) and high purity, it is intended for pharmacology and neuroscience studies.
- Selective antagonist of 5-HT1A receptors.
- High purity suitable for analytical and preclinical research.
- Commonly used for receptor pharmacology and signaling studies.
- Available in small pack sizes for laboratory experiments.
- Molecular weight provided for dosing and calculation purposes.
Medchemexpress LLC Thiophene-2-amidoxim 500mg | 108443-93-2 | 142.18 g/mol | C5H6N2OS | 500 MG
Thiophene-2-amidoxime is a small-molecule synthetic intermediate used in pharmaceutical and medicinal chemistry as a precursor for constructing heterocyclic compounds and for method development in drug synthesis. It is supplied as a solid at research-grade purity for laboratory use.
- High purity suitable for research and synthesis applications.
- Solid form, easy to weigh and handle in standard laboratory procedures.
- Commonly used as a building block in heterocyclic and medicinal chemistry.
- Available in small lab-scale quantities for method development.
- Compatible with common organic solvents and standard synthetic reactions.
eMolecules 36052-27-4 | Methyl 3-aminopicolinate | ChemScene | MFCD08695602 | 152.153 | C7H8N2O2 | 97.000 | COC(=O)c1ncccc1N | 10g | 536904939
Methyl 3-aminopicolinate | ChemScene | 36052-27-4 | MFCD08695602 | 152.153 | C7H8N2O2 | 97.000 | COC(=O)c1ncccc1N | 10g | 536904939
eMolecules 16694-17-0 | 4-Bromo-thiophene-3-carboxylic acid | J & W PharmLab LLC | MFCD01233020 | 207.040 | C5H3BrO2S | 96.000 | OC(=O)c1cscc1Br | 1g | 525338107
4-Bromo-thiophene-3-carboxylic acid | J & W PharmLab LLC | 16694-17-0 | MFCD01233020 | 207.040 | C5H3BrO2S | 96.000 | OC(=O)c1cscc1Br | 1g | 525338107