Thiophenes

Apexbio Technology LLC 4-Methylhistamine dihydrochloride 36376-47-3 1mg

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

4-Methylhistamine dihydrochloride (CAS 36376-47-3) is a selective agonist for the histamine H4 receptor (H4R) displaying a pEC50 of 7 4 0 1 at human H4R It exhibits over 100-fold selectivity for H4R relative to H3R and H2R and over 100 000-fold compared to H1R While affinity for human H4R is moderate it binds rat and mouse H4R with higher affinity (Ki values of 73 nM and 55 nM respectively) In in vivo models 4-Methylhistamine dihydrochloride modulates inflammatory signaling elevating TNF- and NF- B expression via JAK/STAT pathways in response to LPS-induced joint inflammation It serves as a valuable tool in studies of H4R-mediated immune regulation and inflammatory mechanisms

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Lomerizine dihydrochloride | 101477-54-7 | 99.95% | 50 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Lomerizine dihydrochloride is an antagonist of L- and T-type voltage-gated calcium channels. It also antagonizes transient receptor potential channel 5. Lomerizine is a dual L/T-type channel blocker that is used for prophylaxis of migraine.

• Antagonist of L- and T-type voltage-gated calcium channels.
• Demonstrates neuroprotective effects.
• Possesses activity in reversing multidrug resistance.
• Increases cerebral blood flow.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC (E)-1,3-Di(thiophen-2-yl)prop-2-en-1-one | 42811-88-1 | 99.4% | 220.31 | 250 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

(E)-1,3-Di(thiophen-2-yl)prop-2-en-1-one is a chemical compound primarily used as a drug intermediate for the synthesis of various active compounds. It is intended for laboratory research by experienced personnel in appropriately equipped and authorized facilities and has not been fully validated for medical applications.

• Used as a drug intermediate for synthesizing active compounds.
• Intended for laboratory research.
• Appears as a light yellow to yellow solid.
• Requires storage in a cool, well-ventilated area, away from direct sunlight and ignition sources.
• Store powder at -20°C for 3 years, or 4°C for 2 years.
• When in solvent, store at -80°C for 6 months, or -20°C for 1 month.
• Avoid breathing dust or vapors.
• Wear appropriate personal protective equipment during handling.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Medchemexpress LLC Zalunfiban dihydrochloride | 2815778-41-5 | 99.1% | 1 ML

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Zalunfiban dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (reported IC50 ≈ 45 nM) provided as the dihydrochloride salt for research applications, including studies of platelet aggregation and myocardial infarction.

• Potent αIIbβ3 antagonist with reported IC50 ≈ 45 nM.
• Provided as the dihydrochloride salt, soluble in DMSO.
• High purity (99.07%).
• Available as a 10 mM solution in 1 mL vials and in multiple solid sizes.
• Intended for preclinical and biochemical research use.

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 2-Fluoro-3-methyl-6-(methylthio)phenol | ≥97% | CAS 2643368-03-8 | C8H9FOS | 500mg

2-Fluoro-3-methyl-6-(methylthio)phenol | ≥97% | CAS 2643368-03-8 | C8H9FOS | 500mg

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem Thiophene-2 3-dicarboxylic acid | ≥97% | CAS 1451-95-2 | C6H4O4S | 5g

Thiophene-2 3-dicarboxylic acid | ≥97% | CAS 1451-95-2 | C6H4O4S | 5g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem Ethyl 4-methylthiophene-2-carboxylate | ≥95% | CAS 14282-79-2 | C8H10O2S | 500mg

Ethyl 4-methylthiophene-2-carboxylate | ≥95% | CAS 14282-79-2 | C8H10O2S | 500mg

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 5-Formyl-4-methylthiophene-2-boronic acid | ≥95% | CAS 352530-25-7 | C6H7BO3S | 5g

5-Formyl-4-methylthiophene-2-boronic acid | ≥95% | CAS 352530-25-7 | C6H7BO3S | 5g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 3-Bromo-2-(methylsulfonyl)pyridine | ≥97% | CAS 1209459-95-9 | C6H6BrNO2S | 250mg

3-Bromo-2-(methylsulfonyl)pyridine | ≥97% | CAS 1209459-95-9 | C6H6BrNO2S | 250mg

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 2-(Methylthio)thiophene-3-carboxylic acid | ≥97% | CAS 71154-30-8 | C6H6O2S2 | 5g

2-(Methylthio)thiophene-3-carboxylic acid | ≥97% | CAS 71154-30-8 | C6H6O2S2 | 5g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 2-Methylthiophene-3-boronic acid pinacol ester | ≥97% | CAS 910553-12-7 | C11H17BO2S | 10g

2-Methylthiophene-3-boronic acid pinacol ester | ≥97% | CAS 910553-12-7 | C11H17BO2S | 10g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 6-Chloro-2-fluoro-3-(methylthio)pyridine | ≥97% | CAS 2091530-52-6 | C6H5ClFNS | 10g

6-Chloro-2-fluoro-3-(methylthio)pyridine | ≥97% | CAS 2091530-52-6 | C6H5ClFNS | 10g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 2-Chloro-5-fluoro-4-(methylthio)-pyridine | ≥97% | CAS 1820741-49-8 | C6H5ClFNS | 5g

2-Chloro-5-fluoro-4-(methylthio)-pyridine | ≥97% | CAS 1820741-49-8 | C6H5ClFNS | 5g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 5-Chloro-2-fluoro-3-(methylthio)benzoic acid | ≥97% | CAS 2734777-38-7 | C8H6ClFO2S | 5g

5-Chloro-2-fluoro-3-(methylthio)benzoic acid | ≥97% | CAS 2734777-38-7 | C8H6ClFO2S | 5g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More

Aobchem 2-(2-Nitrophenyl)thiophene | ≥97% | CAS 51207-30-8 | C10H7NO2S | 5g

2-(2-Nitrophenyl)thiophene | ≥97% | CAS 51207-30-8 | C10H7NO2S | 5g

Encompass Procurement Services
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More