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GYKI 52466 dihydrochloride is a selective, noncompetitive AMPA/kainate receptor antagonist used in neuroscience research. It is orally active, shows good blood-brain barrier permeability, and has demonstrated anticonvulsant effects. The product is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and is also available in solid quantities for experimental needs.
High purity, suitable for research applications (≈99.8%).
Available as 10 mM solution in DMSO (1 mL) and multiple solid sizes.
Molecular formula C17H17Cl2N3O2, molecular weight 366.24.
Useful for studies of excitatory neurotransmission and neuroprotection.
Demonstrated blood-brain barrier permeability and anticonvulsant activity.
CAS number 2319722-40-0 for the dihydrochloride salt.
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