Thiophenes
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Medchemexpress LLC 3,4-Dibromo-Mal-PEG2-N-Boc | 1807537-43-4 | 95.3% | C15H22Br2N2O6 | 250 MG
3,4-Dibromo-Mal-PEG2-N-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules are designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other ligand targets a specific protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
