Thiophenes
eMolecules 5-Methylthiophene-2-sulfonyl chloride | 55854-45-0 | 1G | Purity: 95%
Combi-Blocks | 5-Methylthiophene-2-sulfonyl chloride | 1G | 55854-45-0 | MFCD05864499
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Apexbio Technology LLC Canertinib dihydrochloride 289499-45-2 100mg
Canertinib dihydrochloride (CAS 289499-45-2) is a small-molecule inhibitor targeting the pan-ErbB family of receptor tyrosine kinases It is designed to irreversibly inhibit ErbB receptors thereby disrupting Akt and MAPK signaling pathways Canertinib dihydrochloride exerts its biological activity primarily through irreversible binding to ErbB receptor family members In cell-based studies Canertinib dihydrochloride demonstrates apoptotic induction and reduced cell viability with an IC50 value of 3 5 nM Apoptosis induction was observed in BT474 (ErbB2-overexpressing breast cancer) and SK-N-SH (neuroblastoma) cell lines Based on these pharmacological properties Canertinib dihydrochloride holds research potential in oncology specifically for investigating ErbB signaling pathways and evaluating anti-tumor effects in cancer models