Cayman Chemical 2-amIno BenzamIdoxIme 5g
A CB2 receptor agonist increases intracellular calcium mobilization induced by CP 55940 in HEK cells co-expressing a chimeric Gaq/05 protein and the human CB2 receptor (EC50 7 78 UM) selective for CB2 over the CB1 receptor (IC50s 133 and 25000 nM respectively) inhibits LPS-induced production of iNOS as well as reduces LPS-induced phosphorylation of ERK1/2 in BV-2 microglia cells at 100 nM inhibits hyperalgesia in a rat model of inflammatory pain induced by complete Freunds adjuvant (ED50 0 1 mg/kg)