Aminals
Medchemexpress LLC Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5) | 8064-90-2 | 99.8% | C24H29N7O6S | 10 MM 1 ML
Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5) is an active compound for toxoplasmic encephalitis inhibition, as well as inhibition in protozoan and bacterial infections. It is for research use only and not sold to patients.
- Active compound for toxoplasmic encephalitis inhibition
- Inhibitor of protozoan infections
- Inhibitor of bacterial infections
- For research use only
Medchemexpress LLC SARS-CoV-2 S trimer protein (XBB.1.16, HEK293, His) | >90.0% | 50UG
Recombinant SARS-CoV-2 spike (S) trimer corresponding to the XBB.1.16 variant, expressed in HEK293 cells and supplied as a C-terminal His-tagged soluble trimer in a buffered, filtered solution. Intended for research use in antigenicity, binding, and immunoassay applications; low endotoxin levels and recommended frozen storage preserve biological activity.
- Expressed in HEK293 cells for mammalian post-translational modifications.
- C-terminal His tag facilitates affinity purification and detection.
- Supplied as a 0.22 μm filtered, buffered solution ready for assays.
- Endotoxin level <1 EU/μg suitable for sensitive bioassays.
- High purity (>90%) as determined by Tris-Bis PAGE.
- Stable when stored frozen; ship on dry ice and avoid repeated freeze-thaw cycles.
Medchemexpress LLC Larsucosterol (trimethylamine) | 97.0% | 509.32 | 1 ML
Larsucosterol (trimethylamine), also known as DUR-928 (trimethylamine), is a cholesterol metabolite that functions as a potent liver X receptor (LXR) antagonist. It serves as an endogenous regulator to decrease lipogenesis and inhibits cholesterol biosynthesis by reducing mRNA levels and inhibiting the activation of SREBP-1.
- Potent liver X receptor (LXR) antagonist
- Decreases lipogenesis
- Inhibits cholesterol biosynthesis by reducing mRNA levels and activating SREBP-1
- Increases cell proliferation and decreases apoptosis in macrophages
- Protects the liver from injury by suppressing hepatic inflammation
Medchemexpress LLC Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19) | 8064-90-2 | 99.8% | C24H29N7O6S | 500 MG
Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19) | 8064-90-2 | 99.8% | C24H29N7O6S | 500 MG
Medchemexpress LLC APRIL/TNFSF13 Trimer 100ug
Recombinant human APRIL/TNFSF13 trimer produced in HEK293 cells and supplied with a His-Flag tag; designed for in vitro receptor binding and functional studies related to B-cell biology and lymphatic malignancies.
- Suitable for receptor binding assays and biochemical characterization.
- Trimeric form mimics the native ligand assembly for functional studies.
- HEK293 expression supports mammalian folding and glycosylation.
- Affinity tags enable straightforward purification and detection.
- Optimized for cell signaling and ligand-receptor interaction experiments.
Medchemexpress LLC TRAIL/TNFSF10 Trimer 100ug | 100ug
TRAIL Protein (TNFSF10) a member of the TNF superfamily is a type II transmembrane protein TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2 and induces apoptosis in tumor or infected cells TRAIL Protein also binds with DR4 DR5 and OPG TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5 Besides TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways[1][2] TRAIL protein is mainly expressed on surface of immune cells such as cytotoxic T cells and natural killer (NK) cell[1] TRAIL/TNFSF10 Protein Human (HEK293 His-Flag) is a recombinant human TRAIL (G118-G281) with N-terminal His and Flag tag which is expressed in HEK293
Medchemexpress LLC Larsucosterol (trimethylamine) | 00-00-0 | 97.0% | 509.32 | C27H46O5S · 0.45 C3H9N | 5 MG
Larsucosterol (trimethylamine) is a research-grade small molecule reported as an LXR antagonist and epigenetic modulator. Supplied as the trimethylamine salt, it is intended for biochemical and pharmacological studies of cholesterol metabolism and related pathways. Available as a solid and as a DMSO solution for in vitro research use only.
- High purity (97.0%) suitable for research applications.
- Molecular weight 509.32 with formula C27H46O5S · 0.45 C3H9N.
- Available in small pack sizes including 5 mg for screening and characterization.
- Solid storage: 4°C, sealed and protected from moisture.
- Solution stability: -80°C for up to 6 months, -20°C for up to 1 month.
- Used to study LXR-related signaling and cholesterol metabolism pathways.
Medchemexpress LLC TL1A/TNFSF15 Trimer 100ug | 100ug
The TL1A protein (VEGI protein) belongs to the tumor necrosis factor (TNF) family and is a receptor for TNFRSF25 and TNFRSF6B TL1A is involved in the activation of NF- B and C-Jun pathways which can be used as a regulator of mucosal immunity and participate in the immune pathway of inflammatory bowel disease (IBD) pathogenesis[1][2] TL1A originates from endothelial cells and inhibits the proliferation of breast cancer epithelial and myeloid tumor cells[3] The human TL1A protein has a transmembrane domain (36-56 a a ) that can be cleaved into membrane-type and soluble peptide fragments TL1A/TNFSF15 Trimer Protein Human (HEK293 His-Flag) is the extracullar part of TL1A protein (D91-L251) produced in HEK293 cells with N-terminal His- and Flag-tag
Medchemexpress LLC Larsucosterol (trimethylamine) | 97.0% | 509.32 | 25 MG
Larsucosterol (trimethylamine) is a cholesterol metabolite that functions as a potent liver X receptor (LXR) antagonist. This endogenous regulator decreases lipogenesis and inhibits cholesterol biosynthesis by reducing mRNA levels and inhibiting the activation of SREBP-1.
- Potent liver X receptor (LXR) antagonist
- Decreases lipogenesis
- Inhibits cholesterol biosynthesis
- Reduces mRNA levels of cholesterol biosynthesis enzymes
- Inhibits activation of SREBP-1
- Increases cell proliferation in macrophages
- Decreases apoptosis in macrophages
- Reduces serum lipid levels in NAFLD models
- Protects liver from injury by suppressing hepatic inflammation