Carboximidamides
N,N'-Diisopropyl-O-(4-nitrobenzyl)isourea 95.0+%, TCI America™
CAS: 2978-11-2 Molecular Formula: C14H21N3O3 Molecular Weight (g/mol): 279.34 MDL Number: MFCD00042046 InChI Key: FYDMCLCYYCIDMZ-UHFFFAOYSA-N Synonym: O-(4-Nitrobenzyl)-N,N′C-diisopropylisourea, 1,3-Diisopropyl-2-(4-nitrobenzyl)isourea PubChem CID: 76317 IUPAC Name: (4-nitrophenyl)methyl N,N'-di(propan-2-yl)carbamimidate SMILES: CC(C)NC(=NC(C)C)OCC1=CC=C(C=C1)[N+](=O)[O-]
2-Chloro-1,3-dimethylimidazolinium Chloride 98.0+%, TCI America™
CAS: 37091-73-9 Molecular Formula: C5H10Cl2N2 Molecular Weight (g/mol): 169.05 MDL Number: MFCD09039290 InChI Key: AEBBXVHGVADBHA-UHFFFAOYSA-M Synonym: 2-chloro-1,3-dimethylimidazolinium chloride,unii-56ka2a1u1d,2-chloro-1,3-dimethyl-4,5-dihydro-1h-imidazol-3-ium chloride,dmc mi,2-chloro-1,3-dimethyl-4,5-dihydroimidazol-1-ium chloride,pubchem16443,2-chloro-1,3-dimethyl-4,5-dihydro-3h-imidazol-1-ium chloride,1h-imidazolium, 2-chloro-4,5-dihydro-1,3-dimethyl-, chloride 1:1,2-chloro-1,3-dimethylimidazolidin-2-ylium chloride PubChem CID: 10176306 IUPAC Name: 2-chloro-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium chloride SMILES: [Cl-].CN1CC[N+](C)=C1Cl
Romifidine 95.0+%, TCI America™
CAS: 65896-16-4 Molecular Formula: C9H9BrFN3 Molecular Weight (g/mol): 258.094 MDL Number: MFCD00868606 InChI Key: KDPNLRQZHDJRFU-UHFFFAOYSA-N Synonym: 2-(2-Bromo-6-fluoroanilino)-2-imidazoline, 2-(2-Bromo-6-fluorophenylamino)-2-imidazoline PubChem CID: 71969 IUPAC Name: N-(2-bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine SMILES: C1CN=C(N1)NC2=C(C=CC=C2Br)F
Creatine Hydrate 98.0+%, TCI America™
CAS: 6020-87-7 Molecular Formula: C4H11N3O3 Molecular Weight (g/mol): 149.15 MDL Number: MFCD00004282 InChI Key: MEJYXFHCRXAUIL-UHFFFAOYSA-N Synonym: creatine monohydrate,creatine hydrate,2-1-methylguanidino acetic acid hydrate,creatine, monohydrate,creatinemonohydrate,unii-9603ln7r2q,glycine, n-aminoiminomethyl-n-methyl-, monohydrate,n-amidinosarcosine monohydrate,n-aminoiminomethyl-n-methylglycine monohydrate,creapure PubChem CID: 80116 IUPAC Name: 2-[carbamimidoyl(methyl)amino]acetic acid;hydrate SMILES: CN(CC(=O)O)C(=N)N.O
Cimetidine 99.0+%, TCI America™
CAS: 51481-61-9 Molecular Formula: C10H16N6S Molecular Weight (g/mol): 252.34 MDL Number: MFCD00133296 InChI Key: AQIXAKUUQRKLND-UHFFFAOYSA-N Synonym: cimetidine,tagamet,tametin,eureceptor,cimetag,acinil,tratul,cimetidina,dyspamet,ulcedine PubChem CID: 2756 ChEBI: CHEBI:3699 IUPAC Name: 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine SMILES: CC1=C(N=CN1)CSCCNC(=NC)NC#N
Brimonidine 98.0+%, TCI America™
CAS: 59803-98-4 Molecular Formula: C11H10BrN5 Molecular Weight (g/mol): 292.14 MDL Number: MFCD00153878 InChI Key: XYLJNLCSTIOKRM-UHFFFAOYSA-N Synonym: brimonidine,bromoxidine,mirvaso,5-bromo-n-4,5-dihydro-1h-imidazol-2-yl-6-quinoxalinamine,5-bromo-n-4,5-dihydro-1h-imidazol-2-yl quinoxalin-6-amine,5-bromo-6-2-imidazolin-2-ylamino quinoxaline,unii-e6gnx3hhte,brimonidine inn:ban,3h brimonidine,5-bromo-6-imidazolin-2-ylamino quinoxaline PubChem CID: 2435 ChEBI: CHEBI:3175 IUPAC Name: 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine SMILES: BrC1=C2N=CC=NC2=CC=C1NC1=NCCN1
Guanylthiourea 98.0+%, TCI America™
CAS: 2114-02-5 Molecular Formula: C2H6N4S Molecular Weight (g/mol): 118.16 MDL Number: MFCD00014472 InChI Key: OKGXJRGLYVRVNE-UHFFFAOYSA-N Synonym: amidinothiourea,guanylthiourea,guthimin,guthimine,2-imino-4-thiobiuret,n-amidinothiourea,thiourea, aminoiminomethyl,thiodicyanodiamidine,diaminomethylidene thiourea,gutimine PubChem CID: 2724563 IUPAC Name: diaminomethylidenethiourea SMILES: C(=NC(=S)N)(N)N
2-(2,6-Dichloroanilino)-2-imidazoline Hydrochloride 98.0+%, TCI America™
CAS: 4205-91-8 Molecular Formula: C9H10Cl3N3 Molecular Weight (g/mol): 266.55 MDL Number: MFCD00036705 InChI Key: ZNIFSRGNXRYGHF-UHFFFAOYSA-N Synonym: clonidine hydrochloride,clonidine hcl,catapres,2-2,6-dichloroanilino-2-imidazoline hydrochloride,chlophazolin,dispaclonidin,normopresan,atensina,barclyd,capresin PubChem CID: 20179 IUPAC Name: N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine;hydrochloride SMILES: C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.Cl
Medchemexpress LLC Atx inhibitor 1 | 2225892-70-4 | 99.3% | 501.30 g/mol | C21H23Cl2N2O6P | 5 MG
ATX inhibitor 1 is a potent autotaxin (ATX) inhibitor with nanomolar activity (IC50 = 1.23 nM by FS-3 assay; 2.18 nM by bis-pNPP). It is supplied as a solid research compound for in vitro and preclinical research use only.
- Potent autotaxin inhibitor with nanomolar IC50 values (1.23 nM FS-3; 2.18 nM bis-pNPP).
- Molecular formula: C21H23Cl2N2O6P.
- Molecular weight: 501.30 g/mol.
- Purity: 99.3% by HPLC.
- Physical form: solid powder.
- Storage: powder -20°C for 3 years or 4°C for 2 years; in solvent -80°C for 6 months.
- Available sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, or 10 mM in DMSO solutions.
- For research use only; not for human therapeutic use.
Medchemexpress LLC PIN1 inhibitor API-1 25mg | 680622-70-2 | 366.30 g/mol | C15H13F3N6O2 | 25 MG
PIN1 inhibitor API-1 is a small-molecule research compound that inhibits Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) and functions as a microRNA activator. Supplied as a solid with high reported purity, it is suitable for in vitro biochemical and cell-based studies and is soluble in DMSO and in certain co-solvent formulations.
Medchemexpress LLC Ask1-in-2 | 2541792-70-3 | 99.6% | 364.38 g·mol⁻¹ | C19H17FN6O | 5 MG
ASK1-IN-2 is a small-molecule, orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 32.8 nM. It is supplied as a white to off-white solid and is available in multiple package sizes and as DMSO solutions for research use; preclinical studies report activity in dextran sulfate sodium (DSS)-induced ulcerative colitis models.
- Potent ASK1 inhibition (IC50 32.8 nM).
- Orally active compound demonstrated in preclinical models.
- Shown to improve DSS-induced ulcerative colitis in mice.
- Blocks ASK1-p38/JNK signaling and reduces inflammatory cytokines.
- High purity (99.6%) and solid, white to off-white physical form.
- Available as solid, solid + solvent, and solution formats for flexible use.
- Powder storage: -20°C for long-term stability; solvent storage guidelines provided.
Medchemexpress LLC Smap-2 (DT-1154) | 1809068-70-9 | 99.5% | 5 MG
SMAP-2 (DT-1154) is a small-molecule, orally active activator of protein phosphatase 2A (PP2A) with demonstrated anti-cancer activity in preclinical studies. It is supplied as a white to off-white solid and includes manufacturer-reported solubility and storage guidance.
- Orally bioavailable PP2A activator with anticancer activity.
- High purity: 99.53% (manufacturer reported).
- Molecular weight 532.57; formula C27H27F3N2O4S.
- Soluble in DMSO (300 mg/mL); in vivo formulation guidance provided.
- Powder storage: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (2 years).
![Medchemexpress LLC 7-ethyl-4-[3-(4-ethylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | 1614245-70-3 | 99.3% | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230936.png-250.jpg)
Medchemexpress LLC 7-ethyl-4-[3-(4-ethylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | 1614245-70-3 | 99.3% | 10 MG
Darigabat is a subtype-selective GABAA positive allosteric modulator used for preclinical research into epilepsy, anxiety, and seizure disorders. It is a small-molecule research compound with confirmed chemical identity and supplier-stated purity.
- CAS number 1614245-70-3.
- Chemical formula C22H21FN4O3S.
- Molecular weight 440.49 g/mol.
- Purity 99.3% (supplier listing).
- Packaging 10 MG; solid storage 4°C, protect from light; in solvent -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC PIN1 inhibitor API-1 50mg | 680622-70-2 | 366.30 | C15H13F3N6O2 | 50 MG
PIN1 inhibitor API-1 is a selective peptidyl-prolyl cis-trans isomerase Pin1 inhibitor (IC50 = 72.3 nM) that binds the Pin1 PPIase domain and has been reported to up-regulate anticancer microRNA biogenesis and suppress hepatocellular carcinoma in preclinical models.
- Selective Pin1 inhibitor (IC50 72.3 nM).
- Molecular formula C15H13F3N6O2; molecular weight 366.30.
- Purity 99.63%.
- Appearance solid; color white to yellow.
- Soluble in DMSO (250 mg/mL); in vivo formulations ≥ 2.17 mg/mL in mixed solvents.
- Available in multiple package sizes including 50 MG.
Medchemexpress LLC Isosinensetin | 17290-70-9 | MFCD21333406 | 99.9% | 372.37 | C20H20O7 | 10 MG
Isosinensetin is a naturally occurring flavonoid research compound used as an inhibitor of HIV-1 protease and protein tyrosine phosphatase 1B (PTP1B), with reported activity against P-glycoprotein. It is provided as a high-purity reagent for biochemical and cell-based studies.
- High purity (99.9%) suitable for research applications.
- Molecular formula C20H20O7; molecular weight 372.37.
- Reported biological activities include PTP1B and HIV-1 protease inhibition and P-gp modulation.
- Recommended storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
- Supplied as a 10 mg vial for small-scale laboratory research.
- 1
- 2