Cyclohexylamines

Medchemexpress LLC 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine | 693228-63-6 | MFCD14155805 | 99.1% | 368.46 | C18H20N6OS | 100 MG

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CYC-116 is a small-molecule research inhibitor of Aurora kinases A and B with low-nanomolar potency. It is used in biochemical and cellular studies to probe cell cycle regulation and antitumor activity, and exhibits additional activity against VEGFR2, Src, Lck, and FLT3.

• Potent inhibitor of Aurora A and B (Ki ≈ 8 and 9 nM).
• Additional kinase activity against VEGFR2, Src, Lck, and FLT3.
• Defined molecular formula and weight: C18H20N6OS, 368.46 g/mol.
• High reported purity (>99% by HPLC) suitable for research applications.
• Supplied in 100 mg research quantities for laboratory use.