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Organic compounds containing an amine group bonded to a carbon atom that is bonded to another carbon atom in a double bond. Enamines are nitrogen analogs of enols.
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PF-562271 besylate is a small-molecule, ATP-competitive and reversible inhibitor of focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (Pyk2). It exhibits low-nanomolar potency in biochemical assays and is used in biochemical and cell-based studies to investigate FAK/Pyk2 signaling, cell migration, and cancer-related pathways. Supplied as a high-purity solid for research use.
Potent ATP-competitive, reversible inhibition of FAK and Pyk2.