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Medchemexpress LLC TO-1187 (TFA) | 98.4% | 795.72 | C36H36F3N9O9 | 10 MG
TO-1187 TFA is a selective PROTAC degrader that targets HDAC6 and recruits cereblon to promote ubiquitination and proteasomal degradation of HDAC6. Supplied as a trifluoroacetic acid salt in solid form, it is intended as a research tool for cellular and preclinical studies investigating HDAC6 biology and PROTAC-mediated target removal.
- Selective HDAC6 degrader with DC50 of 5.81 nM.
- Engages cereblon to induce ubiquitination and proteasomal degradation.
- High chemical purity (98.4%) suitable for biochemical and cellular assays.
- Provided as a solid TFA salt for stable handling and storage.
- Includes analytical documentation such as COA, H NMR, LCMS, and RP-HPLC.
- Storage recommended at 4°C under nitrogen; in solvent store at -80°C (6 months) or -20°C (1 month).
