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Guanidines

Guanidine is a compound with a carbon atom bonded to two nitrogen atoms via singles bonds, and one nitrogen atom via double bond in the following formula: HNC(NH2)2. Guanidine can be considered the nitrogen analogue of carbonic acid.

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Medchemexpress LLC Phenylbiguanide | 55-57-2 | MFCD00035040 | 100.0% | 213.67 g/mol | C8H12ClN5 | 100 G
SDP

Phenylbiguanide hydrochloride is a research-grade small molecule used as a selective agonist of the 5-HT3 receptor in pharmacology and neuronal signaling studies. It exhibits an EC50 of approximately 3.0 μM and has documented solubility and stability data suitable for laboratory use.

  • Selective 5-HT3 receptor agonist (EC50 ≈ 3.0 μM).
  • Chemical identity: CAS 55-57-2; formula C8H12ClN5; molecular weight 213.67 g/mol.
  • High purity for research applications (COA reports 99.96%).
  • Soluble in DMSO (≈40 mg/mL); formulations reported for in vivo dosing.
  • Stable as solid at room temperature; defined solvent storage conditions available.
  • Suitable for GPCR and neuronal signaling assays and related pharmacology studies.

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