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Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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10-Methoxycamptothecin is a natural bioactive derivative of camptothecin used as an antitumor research reagent. It functions as a small-molecule topoisomerase I inhibitor and has shown higher cytotoxicity than 10-hydroxycamptothecin in cell-line studies, making it suitable for cytotoxicity assays and as an ADC payload in research.
CAS number: 19685-10-0.
Molecular formula: C21H18N2O5.
Molecular weight: 378.38 g·mol⁻¹.
Appearance: white to yellow solid.
Purity: 98.06%.
Storage: protect from light; store at 4°C; in solvent: -80°C (6 months), -20°C (1 month).