Oximes
Medchemexpress LLC Glucosylceramide synthase-IN-2 | 2597958-02-4 | 98.62% | C22H20F3N3O4 | 1 ML
Glucosylceramide synthase-IN-2 is a potent, brain-penetrant, and orally active inhibitor of glucosylceramide synthase (GCS). It demonstrates IC50 values of 15 nM for human GCS and 190 nM for mouse GCS, exhibiting noncompetitive inhibition with C8-ceramide and UDP-glucose. This compound is applicable for research related to Gaucher's disease, showing no significant inhibitory activity against SERT or GCase in vitro. In vivo studies confirm good oral and brain exposure in mice, reducing GlcCer concentrations in plasma and cerebral cortex.
- Potent GCS inhibitor
- Brain-penetrant
- Orally active
- Noncompetitive inhibition type with C8-ceramide and UDP-glucose
- Useful for Gaucher's disease research
- Does not significantly inhibit SERT or GCase activity in vitro
- Shows good oral and brain exposure in vivo
Medchemexpress LLC N-hydroxy-3-pyridinecarboximidamide | 1594-58-7 | MFCD00125875; MFCD00265955 | 97.0% | 137.14 | C6H7N3O | 10 G
3-Pyridylamide oxime (N-hydroxy-3-pyridinecarboximidamide) is a small-molecule synthetic intermediate commonly used in pharmaceutical and medicinal chemistry for preparation of target analogues and downstream intermediates. It is supplied as a stable solid intended for research and organic synthesis applications.
- High purity: 97.0% (NMR).
- Molecular formula C6H7N3O; molecular weight 137.14.
- Appearance: white to light yellow solid.
- Storage: powder stable at -20°C (3 years) or 4°C (2 years).
- Available in small pack sizes suitable for laboratory synthesis (10 g).
Chem-Impex International, Inc. Ethyl (hydroxyimino)cyanoacetate | MFCD00002112 | 25G
Ethyl (hydroxyimino)cyanoacetate, MFCD00002112, 25G
Chem-Impex International, Inc. Ethyl (hydroxyimino)cyanoacetate | MFCD00002112 | 5G
Ethyl (hydroxyimino)cyanoacetate, MFCD00002112, 5G
Chem-Impex International, Inc. Ethyl (hydroxyimino)cyanoacetate | MFCD00002112 | 100G
Ethyl (hydroxyimino)cyanoacetate, MFCD00002112, 100G
eMolecules 459-23-4 | Ambeed | 4-Fluorobenzaldehyde oxime | 5g | 491646374 | A234346 | MFCD00133101 | 139.129 | C7H6FNO
Ambeed | (2-Bromo-4-(trifluoromethoxy)phenyl)boronic acid | 100mg | 717401737 | A784081 | 959997-86-5 | MFCD19237163 | 284.820 | C7H5BBrF3O3
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Medchemexpress LLC Milbemycin oxime | 129496-10-2 | 99.5% | 5 MG
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. It is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. This compound binds to glutamate-gated chloride channels and demonstrates inhibitory potency against intestinal nematodes and lung/heart worms.
- Orally active macrolide
- Offers broad-spectrum antiparasitic activity
- Binds to glutamate-gated chloride channels
- Inhibits intestinal nematodes
- Inhibits lung and heart worms
Medchemexpress LLC Acetophenone-13C6 | 125770-94-7 | MFCD04118198 | >98.0% | 126.10 g/mol | C8H8O | 5mg
Acetophenone-13C6 is a deuterated labeled Acetophenone-13C6[1]
AdipoGen Propionaldehyde oxime
Chemical. CAS 627-39-4. Formula C3H7NO. MW 73.09. Synthetic Building block for synthesis.
AdipoGen Propionaldehyde oxime
Chemical. CAS 627-39-4. Formula C3H7NO. MW 73.09. Synthetic Building block for synthesis.
eMolecules Picolinaldehyde oxime | 1193-96-0 | MFCD00006354 | 1g
Oakwood Chemical | Picolinaldehyde oxime | 1g | 537716944 | 227229 | | 1193-96-0 | MFCD00006354 | 122.127 | C6H6N2O
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Medchemexpress LLC Cymoxanil (Standard) | 57966-95-7 | 99.4% | 50 MG
Cymoxanil (Standard) is the analytical standard of Cymoxanil, intended for research and analytical applications. This fungicidal cyanooxime targets plant diseases caused by fungi belonging to the Perenosporales, affecting growth, DNA, and RNA synthesis in Phytophthora.
- Analytical standard
- Intended for research and analytical applications
- Fungicidal cyanooxime
- Targets plant diseases caused by Perenosporales fungi
- Affects growth, DNA and RNA synthesis in Phytophthora