Quaternary ammonium salts
TARGETMOL CHEMICALS INC Cholic acid sodium 1G
Also available in 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity. Purity 99.95%
Apexbio Technology LLC CHOLIC-ACID-SODIUM-100MG
Cholic acid sodium (CAS No 361-09-1) is a bile acid derivative used extensively in biomedical research Its primary application is in the study of lipid metabolism and liver function Originating from natural bile acids it plays a crucial role in modulating cholesterol homeostasis and fat digestion by activating nuclear receptors such as FXR (Farnesoid X receptor) and influencing the bile acid signaling pathway In vitro it exhibits activity in the nanomolar to low micromolar range demonstrating efficacy in modulating metabolic activities Commonly utilized in hepatocyte cell models animal studies and drug screening assays it aids in understanding pathophysiological mechanisms involved in liver diseases and metabolic disorders Experimental concentrations typically depend on the specific research design allowing for versatility in study applications Its comprehensive role in metabolic research makes it a valuable tool for exploring therapeutic strategies in related fields
Apexbio Technology LLC CHOLIC-ACID-SODIUM-200MG
Cholic acid sodium (CAS No 361-09-1) is a bile acid derivative used extensively in biomedical research Its primary application is in the study of lipid metabolism and liver function Originating from natural bile acids it plays a crucial role in modulating cholesterol homeostasis and fat digestion by activating nuclear receptors such as FXR (Farnesoid X receptor) and influencing the bile acid signaling pathway In vitro it exhibits activity in the nanomolar to low micromolar range demonstrating efficacy in modulating metabolic activities Commonly utilized in hepatocyte cell models animal studies and drug screening assays it aids in understanding pathophysiological mechanisms involved in liver diseases and metabolic disorders Experimental concentrations typically depend on the specific research design allowing for versatility in study applications Its comprehensive role in metabolic research makes it a valuable tool for exploring therapeutic strategies in related fields
Medchemexpress LLC Cholic acid sodium | 361-09-1 | 99.85% | 430.55 | 50 G
Cholic acid sodium | 361-09-1 | 99.85% | 430.55 | 50 G
Medchemexpress LLC Cholic acid sodium | 361-09-1 | 99.9% | 430.55 | 10 G
Cholic acid sodium is an endogenous metabolite and a major primary bile acid that is produced in the liver and typically conjugated with glycine or taurine. It plays a role in facilitating fat absorption and cholesterol excretion and is orally active. This product is intended for research use only.
- Major primary bile acid.
- Produced in the liver and typically conjugated with glycine or taurine.
- Facilitates fat absorption and cholesterol excretion.
- Orally active.
- Competitively binds Na+/taurocholate cotransporting polypeptide (NTCP) on HepG2 cells, inhibiting the uptake of CA-nanoliposomes-Doxorubicin-HCl.
- In vivo, it has been shown to decrease SHP protein expression and increase CYP2D6 expression and activity.
Medchemexpress LLC Cholic acid | 81-25-4 | 99.8% | 408.57 | 1 G
Cholic acid is a major primary bile acid produced in the liver, commonly conjugated with glycine or taurine. It plays a crucial role in facilitating fat absorption and cholesterol excretion, and is orally active.
- Major primary bile acid
- Produced in the liver
- Conjugated with glycine or taurine
- Facilitates fat absorption
- Aids cholesterol excretion
- Orally active
- Competitively binds Na+/taurocholate cotransporting polypeptide (NTCP)
- Decreases SHP protein expression
- Increases CYP2D6 expression and activity
Medchemexpress LLC Stearoyl-L-carnitine chloride | 32350-57-5 | 99.9% | 100 MG
Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. It acts as a less potent inhibitor of GlyT2 and inhibits glycine responses by 16.8% at concentrations up to 3 μM. This compound is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI), and subjective memory complaint (SMC), suggesting its potential role in neurodegenerative research.
- Endogenous long-chain acylcarnitine
- Acts as a less potent inhibitor of GlyT2
- Inhibits glycine responses by 16.8% at concentrations up to 3 μM
- Inhibits Na+-dependent [³H]carnitine uptake by approximately 50% in HPCT cells
- Associated with neurological conditions such as Alzheimer's disease