Alcohols and polyols
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- (1)
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- (462)
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- (1)
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Filtered Search Results
eMolecules N-FMOC-N-2-PHENYLETHYL-G 10G
5000160115 N-FMOC-N-2-PHENYLETHYL-G 10G
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Medchemexpress LLC Azasetron hydrochloride | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 100 MG
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Azasetron hydrochloride is a benzamide derivative that functions as a potent and selective antagonist of the 5-HT3 receptor, demonstrating an IC50 of 0.33 nM against this target. It has been investigated for its potential in studies related to chemotherapy-induced nausea and vomiting (CINV) and has shown the ability to penetrate the skin and enter systemic circulation in in vivo models.
- Mechanism of action: Potent and selective 5-HT3 receptor antagonist.
- Target affinity: IC50 of 0.33 nM for 5-HT3 receptor.
- Chemical classification: Benzamide derivative.
- Molecular formula: C17H21Cl2N3O3.
- Molecular weight: 386.27.
- Purity: 99.76%.
- Physical characteristics: White to off-white solid.
- Solubility: Soluble in water (20 mg/mL) and DMSO (2.22 mg/mL).
- Research application: Used in CINV studies.
- Pharmacokinetic property: Penetrates skin and enters systemic circulation in animal models.
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Medchemexpress LLC HY-N0899 5mg Medchemexpress, Wilforine CAS:11088-09-8 Purity:>98%
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Medchemexpress, HY-N0899 5mg Wilforine CAS:11088-09-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-N0629 5mg Medchemexpress, Maslinic acid CAS:4373-41-5 Purity:>98%
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Medchemexpress, HY-N0629 5mg Maslinic acid CAS:4373-41-5 Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α , which is required for p65 activation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-N0615 5mg Medchemexpress, Notoginsenoside R1 CAS:80418-24-2 Purity:>98%
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Medchemexpress, HY-N0615 5mg Notoginsenoside R1 CAS:80418-24-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-B1900 10mg Medchemexpress, Methylprednisolone succinate CAS:2921-57-5 Purity:>98%
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Medchemexpress, HY-B1900 10mg Methylprednisolone succinate CAS:2921-57-5 Methylprednisolone succinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Platyconic acid A | 68051-23-0 | 99.1% | 1239.31 | 5 MG
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Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation.
- Inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.
- Decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.
- Stored at 4°C, protected from light.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- Soluble in H2O at 25 mg/mL (20.17 mM) with ultrasonic assistance.
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Medchemexpress LLC HY-14648 5g Medchemexpress, Dexamethasone CAS:50-02-2 Purity:>98%
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Medchemexpress, HY-14648 5g Dexamethasone CAS:50-02-2 Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-13780 10mg Medchemexpress, Vinblastine (sulfate) CAS:143-67-9 Purity:>98%
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Medchemexpress, HY-13780 10mg Vinblastine (sulfate) CAS:143-67-9 Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules DI-TERT-BUTYL N N-DIISOPRO 50G
5000225761 DI-TERT-BUTYL N N-DIISOPRO 50G
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Medchemexpress LLC Mefuparib hydrochloride | 1449746-00-2 | 98.6% | 334.77 | 5 MG
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Mefuparib hydrochloride is an orally active, substrate-competitive, and selective inhibitor of PARP1/2, with IC50 values of 3.2 nM and 1.9 nM respectively. It is known to induce apoptosis and exhibits significant anticancer activity both in vitro and in vivo.
- Orally active.
- Substrate-competitive and selective PARP1/2 inhibitor.
- Induces apoptosis.
- Possesses prominent anticancer activity in vitro and in vivo.
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Medchemexpress LLC SAR407899 (hydrochloride) | 923262-96-8 | 99.1% | 280.75 | 5 MG
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SAR407899 hydrochloride is a selective, potent, and ATP-competitive ROCK inhibitor. It has an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. It inhibits ROCK-2 more effectively than ROCK-1. This product exhibits potent vasorelaxant activity in various isolated arteries and dose-dependently lowers blood pressure in hypertensive SHRs. It also increases penile length in healthy and diabetic rabbits.
- Selective and potent ROCK inhibitor
- ATP-competitive mechanism of action
- Inhibits MYPTT696 phosphorylation
- Blocks thrombin-induced effects
- Inhibits cell proliferation and migration
- Potent vasorelaxant activity
- Reduces blood pressure
- Increases penile length
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Medchemexpress LLC tert-Butyl p-Toluate | 13756-42-8 | C₁₂H₁₆O₂ | 10 G
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tert-Butyl p-Toluate (tert-Butyl p-methylbenzoate) is a synthetic intermediate useful for pharmaceutical synthesis. It appears as a liquid, colorless to light yellow.
- Useful for pharmaceutical synthesis
- Appears as a liquid
- Colorless to light yellow
- Store at room temperature for 3 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
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Medchemexpress LLC HY-15371 200mg Medchemexpress, Forskolin CAS:66575-29-9 Purity:>98%
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Medchemexpress, HY-15371 200mg Forskolin CAS:66575-29-9 Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / INCB 3284 / 10mg / 448038939 / HY-15450A / / 887401-92-5 / [null] / 520.553 / C26H31F3N4O4
Medchem Express / INCB 3284 / 10mg / 448038939 / HY-15450A / / 887401-92-5 / [null] / 520.553 / C26H31F3N4O4
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