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Filtered Search Results
Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | 99.5% | 458.08 | C27H40ClN3O | 10 MG
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Nevanimibe hydrochloride is the hydrochloride salt of Nevanimibe, an orally active, selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) with demonstrated activity in preclinical studies. It is provided for research use in solid and solution forms and has been characterized for potency and basic physicochemical properties.
- Selective ACAT1 inhibitor with low-nanomolar potency
- Demonstrated activity against ACAT2 in cellular assays
- Induces apoptosis in cell models relevant to adrenocortical tissues
- Chemical formula C27H40ClN3O and molecular weight 458.08
- Available as solid and DMSO solution formats for research use
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Chem-Impex Ninhydrin 1kg 112440014 00462 0 000 485-47-2 MFCD00003791 178 143 C9H6O4
Chem-Impex Ninhydrin 1kg 112440014 00462 0 000 485-47-2 MFCD00003791 178 143 C9H6O4
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Medchemexpress LLC mAChR-IN-1 hydrochloride | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 100MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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mAChR-IN-1 hydrochloride is a research-grade muscarinic acetylcholine receptor antagonist provided for laboratory use. It exhibits potent inhibitory activity against mAChR with a reported IC50 of 17 nM. The compound is supplied as a hydrochloride salt, with formula C23H26ClIN2O2 and molecular weight 524.82 g/mol.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Taltobulin hydrochloride | 228266-40-8 | 99.3% | 510.11 Da | C27H44ClN3O4 | 100 MG
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Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin and a potent antimicrotubule agent. It inhibits tubulin polymerization, disrupts microtubule organization, and induces mitotic arrest, and is supplied as a solid research reagent for in vitro and in vivo studies.
- Potent tubulin inhibitor with low-nanomolar activity in tumor cell lines.
- High purity suitable for research applications.
- Supplied as a solid powder for solution preparation in DMSO or aqueous buffers.
- Recommended solvent and formulation guidance provided for in vitro and in vivo use.
- Store sealed at 4°C; solutions stable at -80°C for long-term storage.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Azasetron hydrochloride (Y-25130 hydrochloride) | 123040-16-4 | 99.8% | C17H21Cl2N3O3 | 50 MG
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Azasetron hydrochloride is a potent and selective 5-HT3 receptor antagonist, a benzamide derivative used in the study of Chemotherapy-induced nausea and vomiting (CINV). This product is for research use only. It has an IC50 for the 5-HT3 Receptor of 0.33 nM and appears as a white to off-white solid with a molecular weight of 386.27.
- Potent and selective 5-HT3 receptor antagonist
- Used in studies for chemotherapy-induced nausea and vomiting (CINV)
- Effectively penetrates skin and enters systemic circulation (demonstrated in in vivo studies)
- Soluble in H2O (20 mg/mL) and DMSO (2.22 mg/mL)
- Clear solution of 50 mg/mL in PBS achievable for in vivo dissolution
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Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | MFCD04113213 | >98.0% | 374.82 g·mol⁻¹ | C17H19ClN6O2 | 100 MG
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Zoniporide hydrochloride hydrate is a research-use small molecule that potently and selectively inhibits the sodium-hydrogen exchanger isoform 1 (NHE-1). It is used in cellular and pharmacological studies to probe NHE-1-mediated pathways such as cardioprotection and cell volume regulation. Available in solid form and as a DMSO solution for laboratory assays.
- Potent NHE-1 inhibitor (human NHE-1 IC50 = 14 nM).
- Shows >150-fold selectivity versus other NHE isoforms.
- Inhibits ex vivo NHE-1-dependent platelet swelling (IC50 = 59 nM).
- Supplied in solid and 10 mM DMSO solution formats for flexibility.
- Intended for research use only.
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Medchemexpress LLC BMT-090605 (hydrochloride) | 2231664-45-0 | 98.8% | 400.90 g/mol | C21H25ClN4O2 | 10 MG
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BMT-090605 hydrochloride is a research-grade small-molecule hydrochloride salt that functions as a potent inhibitor of adaptor protein-2 associated kinase 1 (AAK1), with reported activity against BIKE and GAK. It is supplied as a solid for use in in vitro kinase assays and preclinical pharmacology studies.
- Potent AAK1 inhibitor with low-nanomolar activity.
- Also inhibits BIKE and GAK, supporting broad kinase profiling.
- High purity (≈98.8%) suitable for research applications.
- Supplied as a solid light yellow powder for convenient handling.
- Stable when stored at -20°C as a powder for long-term storage.
- Packaged in small milligram quantities for laboratory use.
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Medchemexpress LLC Eperisone hydrochloride | 56839-43-1 | MFCD00941459 | 100.0% | 500 MG
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Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an orally active antispastic agent with a vasodilator effect, used for the research of muscle stiffness and pain. It is a potent and selectively P2X7 receptor antagonist, and also shows antagonism for human P2X3. Eperisone Hydrochloride works by relaxing both skeletal muscles and vascular smooth muscles, demonstrating a variety of effects such as reduction of myotonia, improvement of circulation and suppression of the pain reflex.
- Orally active antispastic agent
- Vasodilator effect
- Used for research of muscle stiffness and pain
- Potent and selective P2X7 receptor antagonist
- Shows antagonism for human P2X3
- Relaxes both skeletal muscles and vascular smooth muscles
- Reduces myotonia
- Improves circulation
- Suppresses the pain reflex
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Medchemexpress LLC Zoniporide hydrochloride hydrate | 863406-85-3 | MFCD04113213 | 99.4% | 374.82 g/mol | C17H19ClN6O2 | 1 ML
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Zoniporide hydrochloride hydrate is the hydrochloride hydrate salt of zoniporide (CP-597396), a potent and selective inhibitor of the sodium-hydrogen exchanger type 1 (NHE-1). Supplied as a ready-to-use solution, it is intended for research applications targeting membrane transporter and ion-channel pathways.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Potent, selective NHE-1 inhibitor; reported IC50 ≈ 14 nM.
- High purity, typically ≥99.4% (HPLC).
- Molecular formula C17H19ClN6O2; molecular weight 374.82 g/mol.
- Soluble in DMSO (~20 mg/mL); may require warming or sonication.
- Store sealed, away from moisture; in solvent store -80°C for long term, -20°C for short term.
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Medchemexpress LLC Amxi-5001 hydrochloride | 00-00-0 | 98.1% | 493.92 g/mol | C25H21ClFNO3 | 5 MG
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AMXI-5001 hydrochloride is a research-use small-molecule hydrochloride salt with dual PARP1/2 inhibitory activity and microtubule polymerization inhibition. It is intended for preclinical biochemical and cellular studies and is supplied with analytical specifications.
- Dual PARP1/2 and microtubule polymerization inhibitory activity.
- Suitable for in vitro and in vivo preclinical research.
- Hydrochloride salt form improves solubility for formulation.
- Soluble in DMSO at high concentration (≈100 mg/mL) for stock solutions.
- Solid storage recommended at 4°C; solutions stable at -80°C for extended storage.
- High chemical purity reported (~98%).
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Medchemexpress LLC m-PEG-NH2 hydrochloride | 99.1% | 2000 Da (average) | Polydisperse PEG (repeating unit C2H4O) hydrochloride (no single chemical formula) | 25 MG
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Amine-terminated methoxy polyethylene glycol hydrochloride with an average molecular weight of 2000 Da. This polydisperse PEG reagent is used as a building block and barrier-permeation modifier for preparing hybrid gels and for size-exclusion applications in biochemical assays.
- Amine-terminated methoxy polyethylene glycol hydrochloride with average molecular weight 2000 Da.
- Polydisperse polymeric reagent suitable for gel and biochemical assay applications.
- Helps AdSEC gels separate from complex biological mixtures such as blood, urine, sweat, and tears.
- Reported purity 99.13%.
- Soluble in DMSO at 100 mg/mL (ultrasonic recommended).
- Store at -20°C and protect from light; in solvent store at -80°C for up to 6 months or -20°C for 1 month.
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Medchemexpress LLC Sevelamer (hydrochloride) | 152751-57-0 | 98.0% | 186.08 (monomer) | 1 G
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Sevelamer (hydrochloride) is an orally active phosphate binding agent primarily used for research into hyperphosphatemia associated with chronic kidney disease. This substance consists of polyallylamine crosslinked with epichlorohydrin. It has a molecular weight of 186.08 (monomer) and is stable under recommended storage conditions, appearing as a white to off-white solid. It is classified as harmful to aquatic life with long lasting effects.
- Orally active phosphate binding agent
- Used for research of hyperphosphatemia with chronic kidney disease
- Decreases serum levels of gut-derived uremic toxins
- Reduces serum phosphate levels
- Stable under recommended storage conditions
- Solid appearance
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Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 1 ML
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Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research. It exhibits minimal effect on the amounts of conjugated dopamine (DA) present in superfusate of slices from rat striatum. This compound contains an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
- Irreversible and selective monoamine oxidase A (MAO-A) inhibitor
- Used for scientific research
- Minimal impact on conjugated dopamine (DA) in rat striatum slices
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Stable under recommended storage conditions
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Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 25 MG
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Alosetron Hydrochloride is a potent and highly selective serotonin 5-HT3 receptor antagonist used for the research of irritable bowel syndrome (IBS). It blocks fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, and attenuates visceral nociceptive effects.
- Potent and highly selective serotonin 5-HT3 receptor antagonist
- Used for research of irritable bowel syndrome (IBS)
- Blocks fast 5HT3-mediated depolarization of myenteric and submucosal neurons
- Attenuates visceral nociceptive effect of rectal distension
- Exhibits anti-inflammatory effects
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Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.9% | C22H25Cl2FN4O3 | 100 MG
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Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective, and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. It selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy and has antitumour activity.
- Potent, selective, and orally active EGFR tyrosine kinase inhibitor
- Selectively inhibits EGF-stimulated tumor cell growth
- Blocks EGF-stimulated EGFR autophosphorylation
- Induces autophagy
- Has antitumour activity
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